• Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 

      Stein Emil, Vollset; Ababneh, Hazim S; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ...
    • Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021 

      Dana, Bryazka; Reitsma, Marissa B; Abate, Yohannes Habtegiorgis; Abd Al Magied, Abdallah H A; Abdelkader, Atef; ... more authors ( Elsevier , 2024 , Article)
      BackgroundSmoking is the leading behavioural risk factor for mortality globally, accounting for more than 175 million deaths and nearly 4·30 billion years of life lost (YLLs) from 1990 to 2021. The pace of decline in smoking ...
    • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Michael, Brauer; Roth, Gregory A; Aravkin, Aleksandr Y; Zheng, Peng; Abate, Kalkidan Hassen; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to ...
    • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Naghavi, Mohsen; Ong, Kanyin Liane; Aali, Amirali; Ababneh, Hazim S.; Abate, Yohannes Habtegiorgis; ... more authors ( Elsevier , 2024 , Article)
      Background: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy ...
    • Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020 

      Little, Julie Anne; Congdon, Nathan G.; Resnikoff, Serge; Braithwaite, Tasanee; Leasher, Janet; ... more authors ( Springer , 2024 , Article)
      Background: Uncorrected refractive error (URE) is a readily treatable cause of visual impairment (VI). This study provides updated estimates of global and regional vision loss due to URE, presenting temporal change for ...
    • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 

      Natalia V, Bhattacharjee; Schumacher, Austin E; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      Background Accurate assessments of current and future fertility—including overall trends and changing population age structures across countries and regions—are essential to help plan for the profound social, economic, ...
    • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Alize J, Ferrari; Santomauro, Damian Francesco; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2024 , Article)
      Background Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...
    • Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021 

      Hmwe Hmwe, Kyu; Vongpradith, Avina; Dominguez, Regina-Mae Villanueva; Ma, Jianing; Albertson, Samuel B; ... more authors ( Elsevier , 2024 , Article)
      BackgroundDiarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age ...
    • Global, regional, and national burden of asthma and atopic dermatitis, 1990–2021, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021 

      Jiyeon, Oh; Kim, Soeun; Kim, Min Seo; Abate, Yohannes Habtegiorgis; Abd ElHafeez, Samar; ... more authors ( Elsevier , 2025 , Article)
      BackgroundAsthma and atopic dermatitis are common allergic conditions that contribute to substantial health loss, economic burden, and pain across individuals of all ages worldwide. Therefore, as a component of the Global ...
    • Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021 

      Kanyin Liane, Ong; Stafford, Lauryn K; McLaughlin, Susan A; Boyko, Edward J; Vollset, Stein Emil; ... more authors ( Elsevier , 2023 , Article)
      BackgroundDiabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global ...
    • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Jaimie D, Steinmetz; Seeher, Katrin Maria; Schiess, Nicoline; Nichols, Emma; Cao, Bochen; ... more authors ( Elsevier , 2024 , Article)
      Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous ...
    • Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 

      Austin, Carter; Zhang, Meixin; Tram, Khai Hoan; Walters, Magdalene K; Jahagirdar, Deepa; ... more authors ( Elsevier , 2024 , Article)
      BackgroundAs set out in Sustainable Development Goal 3.3, the target date for ending the HIV epidemic as a public health threat is 2030. Therefore, there is a crucial need to evaluate current epidemiological trends and ...
    • Global, Regional, and National Burden of Nontraumatic Subarachnoid Hemorrhage: The Global Burden of Disease Study 2021. 

      Rautalin, Ilari; Volovici, Victor; Stark, Benjamin A; Johnson, Catherine O; Kaprio, Jaakko; ... more authors ( American Medical Association , 2025 , Article)
      Nontraumatic subarachnoid hemorrhage (SAH) represents the third most common stroke type with unique etiologies, risk factors, diagnostics, and treatments. Nevertheless, epidemiological studies often cluster SAH with other ...
    • Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 

      Marie, Ng; Gakidou, Emmanuela; Lo, Justin; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2025 , Article)
      BackgroundOverweight and obesity is a global epidemic. Forecasting future trajectories of the epidemic is crucial for providing an evidence base for policy change. In this study, we examine the historical trends of the ...
    • Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 

      Jessica A, Kerr; Patton, George C; Cini, Karly I; Abate, Yohannes Habtegiorgis; Abbas, Nasir; ... more authors ( Elsevier , 2025 , Article)
      BackgroundDespite the well documented consequences of obesity during childhood and adolescence and future risks of excess body mass on non-communicable diseases in adulthood, coordinated global action on excess body mass ...
    • Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 

      Comfort, Haley; McHugh, Theresa A; Schumacher, Austin E; Harris, Ashley; May, Erin A; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Stillbirth is a devastating and often avoidable adverse pregnancy outcome. Monitoring stillbirth levels and trends—in a comprehensive manner that leaves no one uncounted—is imperative for continuing progress ...
    • Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021 

      Letourneau, Ian D; Abate, Yohannes Habtegiorgis; Abdelmasseh, Michael; Abu-Gharbieh, Eman; Adane, Tigist Demssew; ... more authors (2024 , Article)
      BackgroundAppendicitis is a common surgical emergency that poses a large clinical and economic burden. Understanding the global burden of appendicitis is crucial for evaluating unmet needs and implementing and scaling up ...