تصفح حسب الموضوع "Calcium signalling"
السجلات المعروضة 1 -- 3 من 3
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Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function.
( Oxford University Press , 2020 , Article)The cardiac ryanodine receptor (RyR2), which mediates intracellular Ca2+ release to trigger cardiomyocyte contraction, participates in development of acquired and inherited arrhythmogenic cardiac disease. This study was ... -
KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals
( Nature Research , 2021 , Article)Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs. Cells express thousands of mostly mobile ... -
Opposing calcium-dependent signalling pathways control skeletal muscle differentiation by regulating a chromatin remodelling enzyme
( Nature Publishing Group , 2015 , Article)Calcium signalling is important for differentiation-dependent gene expression, but is also involved in other cellular functions. Therefore, mechanisms must exist to distinguish calcium signalling relevant to differentiation. ...