Browsing by Subject "Cytotoxicity"
Now showing items 1-19 of 19
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Cerium oxide NPs mitigate the amyloid formation of α-synuclein and associated cytotoxicity
( Dove Medical Press Ltd. , 2019 , Article)Aim: Among therapeutic proposals for amyloid-associated disorders, special attention has been given to the exploitation of nanoparticles (NPs) as promising agents against aggregation. Methods: In this paper, the inhibitory ... -
Chemical composition, cytotoxicity effect and antimicrobial activity of Ceratonia siliqua essential oil with preservative effects against Listeria inoculated in minced beef meat
( Elsevier B.V. , 2011 , Article)The present study describes the phytochemical profile and the protective effects of Ceratonia siliqua pods essential oil (CsEO), a food and medicinal plant widely distributed in Tunisia. Twenty five different components ... -
Cytotoxic homoisoflavonoids from the bulbs of Bellevalia flexuosa
( Elsevier B.V. , 2018 , Article)Four new homoisoflavonoids, 7-O-methyl-8-demethoxy-3′-hydroxy-3,9-dihydropunctatin (4), 6-hydroxy-8-demethoxy-4′-O-methyl-3,9-dihydropunctatin (8), 7,4′-O-dimethyl-8-demethoxy-3,3′-dihydroxy-3,9-dihydropunctatin (13), and ... -
Design of hybrid clay/ polypyrrole decorated with silver and zinc oxide nanoparticles for anticorrosive and antibacterial applications
( Elsevier , 2020 , Article)In this work, a novel and cost-effective bentonite intercalated with polypyrrole Zinc oxide-silver nanocomposite (B-PPy/ZnO) hybrid material was prepared via in situ photopolymerization of pyrrole in the presence of silanized ... -
Development of biopolymeric hybrid scaffold-based on aac/go/nhap/tio2 nanocomposite for bone tissue engineering: In-vitro analysis
( MDPI AG , 2021 , Article)Bone tissue engineering is an advanced field for treatment of fractured bones to re-store/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone ... -
Dual Role of Lanthanum Oxide Nanoparticles Functionalized Co-Polymeric Micelle for Extended Anti-Cancer Drug Delivery
( Wiley-Blackwell , 2019 , Article)In this study, the paclitaxel (PTX) - loaded A?B type di-block polymeric micelles poly xylitol sebacate-poly methylmethacrylic acid/Lanthanum Oxide/paclitaxel (PXS-PMAA/LO/PTX) were designed and Lanthanum oxide nanoparticles ... -
Exploring the interaction of synthesized nickel oxide nanoparticles through hydrothermal method with hemoglobin and lymphocytes: Bio-thermodynamic and cellular studies
( Elsevier B.V. , 2020 , Article)The NiO NPs were synthesized by hydrothermal method and their interaction with Hb was investigated by employing fluorescence, UV?vis absorption techniques as well as docking studies. Also, the cytotoxic impacts of NiO NPs ... -
Nanomedicine tactics in cancer treatment: Challenge and hope
( Elsevier Ireland Ltd , 2022 , Article)Defeating cancer is the ultimate challenge and goal of oncologists, facing various obstacles along with finding effective anti-cancer therapies and understanding drug delivery mechanisms. Additionally, the translation of ... -
Olive oil by‑product’s contribution to the recovery of phenolic compounds from microalgal biomass: biochemical characterization, anti‑melanogenesis potential, and neuroprotective effect
( Springer , 2022 , Article)Recently, the use of microalgae in the treatment of olive mill wastewater as a safe method for reducing pollutants has gained more attention. However, the contribution of such by-product to the improvement of the pharmacological ... -
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
( Elsevier , 2021 , Article)The aim of this study was to prepare, characterize, and determine the in vitro anticancer effects of platinum-doped magnesia (Pt/MgO) nanoparticles. The chemical compositions, functional groups, and size of nanoparticles ... -
Phenethyisoquinoline alkaloids from the leaves of Androcymbium palaestinum
( Elsevier , 2020 , Article)Thirteen compounds were isolated from the methanolic extract of the leaves of Androcymbium palaestinum Baker (Colchicaceae). Of these, three were new, two were new natural products, and eight were known. The new isolated ... -
Pistacia lentiscus L. Distilled Leaves as a Potential Cosmeceutical Ingredient: Phytochemical Characterization, Transdermal Diffusion, and Anti‐Elastase and Anti‐Tyrosinase Activities
( MDPI , 2022 , Article)The present work was performed to investigate the phenolic composition of P. lentiscus L. distilled leaves (PDL) and examine its potential against certain key enzymes related to skin aging. High‐pressure liquid chromatography ... -
Structure-activity relationship investigation of methoxy substitution on anticancer pyrimido[4,5-c]quinolin-1(2H)-ones
(2013 , Article)Pyrimido[4,5-c]quinolin-1(2H)-one derivatives were shown to exert interesting biological activities including anticancer, antimicrobial, and cardiovascular. Substitution with methoxy groups played a crucial role in the ... -
Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
( Elsevier , 2023 , Article)Colon cancer (CRC) is the second leading cause of death and the third most diagnosed cancer worldwide. Although curcumin (CUR) has demonstrated a potent anticancer activity, it is characterized by its poor solubility, low ... -
Synthesis, characterization and biological applications of selenoureas having ferrocene and substituted benzoyl functionalities
( Elsevier Ltd , 2019 , Article)In this article we have comprehensively reported the synthesis, complete chemical characterization (FTIR, multinuclear NMR, single crystal XRD, CHNS, AAS) and biological applications of seventeen ferrocene incorporated ... -
Synthesis, characterization, and evaluation of cytotoxicity, antioxidant, antifungal, antibacterial, and cutaneous wound healing effects of copper nanoparticles using the aqueous extract of Strawberry fruit and L-Ascorbic acid
( Elsevier , 2020 , Article)© 2020 Elsevier Ltd Fragaria ananassa, also known as “Strawberry” is a common species in Iran and widely used for its anti-inflammatory, anti-ulcer, astringent, anti-allergic, antibacterial, antifungal, and antidiarrheal ... -
Synthesis, characterization, lipoxygenase, and tyrosinase inhibitory activities of non- cytotoxic titanium(III) and (IV) hydrazide complexes
( Chemical Society of Ethiopia , 2023 , Article)Ti(III) and (IV) hydrazide complexes were synthesized, characterized, and screened for their tyrosinase and lipoxygenase inhibitory and cytotoxic activities. The geometry of Ti(III) hydrazide complexes is tentatively ... -
The replacement of five consecutive amino acids in the cyt1a protein of bacillus thuringiensis enhances its cytotoxic activity against lung epithelial cancer cells
( MDPI AG , 2018 , Article)Cyt1A protein is a cytolytic protein encoded by the cyt gene of Bacillus thuringiensis subsp. israelensis (Bti) as part of the parasporal crystal proteins produced during the sporulation. Cyt1A protein is unique compared ... -
Vitamin K1 as a potential molecule for reducing single-walled carbon nanotubes-stimulated �-synuclein structural changes and cytotoxicity
( Dove Medical Press Ltd. , 2019 , Article)Aims: Different kinds of vitamins can be used as promising candidates to mitigate the structural changes of proteins and associated cytotoxicity stimulated by NPs. Therefore, the structural changes of �-syn molecules and ...