Browsing by Subject "Drug delivery"
Now showing items 1-20 of 30
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A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies
( Elsevier B.V. , 2016 , Article)Membrane extrusion was investigated for predicting the stability of soya phosphatidylcholine liposomes and surfactosomes (Tween 80-enriched liposomes) to nebulization. Formulations were prepared with or without cholesterol, ... -
Application of gelatin nanoconjugates as potential internal stimuli-responsive platforms for cancer drug delivery
( Elsevier B.V. , 2020 , Article)Nanoparticles (NPs) have been continuously utilized for different implementations, most particularly for cancer drug delivery. A large number of NP-based drug delivery systems (DDSs) have been explored for cancer therapy ... -
Carbon nanotubes: Applications in cancer therapy and drug delivery research
( Elsevier , 2018 , Book chapter)Carbon nanotubes (CNTs) are novel nanocarrier systems that have a wide range of applications in science, engineering, and, the environment. Owing to the possible functionalization of CNTs (i.e., surface-engineering of the ... -
Design characteristics of inhaler devices used for pulmonary delivery of medical aerosols
( Springer International Publishing , 2016 , Book chapter)For the treatment of respiratory diseases, it is vital to deliver therapeutic doses of drugs to specific regions in the tracheobronchial tree (TBT) of the lung with maximal efficiency and minimal wastage of medication. ... -
Development of biopolymeric hybrid scaffold-based on aac/go/nhap/tio2 nanocomposite for bone tissue engineering: In-vitro analysis
( MDPI AG , 2021 , Article)Bone tissue engineering is an advanced field for treatment of fractured bones to re-store/regulate biological functions. Biopolymeric/bioceramic-based hybrid nanocomposite scaffolds are potential biomaterials for bone ... -
Effect of anions on the structural, morphological and dielectric properties of hydrothermally synthesized hydroxyapatite nanoparticles
( Springer Nature , 2020 , Article)Synthetic nano hydroxyapatites (HA) have been considered as potential biomaterials for bone tissue engineering applications because of its excellent biological properties. The present work deals with the synthesis of HA ... -
Enhancement of gemcitabine against pancreatic cancer by loading in mesoporous silica vesicles
( Elsevier B.V. , 2017 , Article)Gemcitabine (Gem) is currently the first-line chemotherapeutic drug in management of pancreatic cancer, however the therapeutic efficacy of Gem is limited due to its short half-life and poor cell membrane permeability. ... -
Enzyme?polymeric/inorganic metal oxide/hybrid nanoparticle bio-conjugates in the development of therapeutic and biosensing platforms
( Elsevier B.V. , 2021 , Article)Background: Because enzymes can control several metabolic pathways and regulate the production of free radicals, their simultaneous use with nanoplatforms showing protective and combinational properties is of great interest ... -
Exosomes: Multiple-targeted multifunctional biological nanoparticles in the diagnosis, drug delivery, and imaging of cancer cells
(2020 , Article)Exosomes are biological nanoparticles (30−150 nm) secreted in the extracellular area from all of cells, that mediate intercellular message. Exosomes act as the carriers for numerous proteins, DNAs, RNAs and cell-signaling ... -
Fabrication, characterization and optimization of nanostructured lipid carrier formulations using Beclomethasone dipropionate for pulmonary drug delivery via medical nebulizers
( Elsevier , 2021 , Article)Aerosolization is a non-invasive approach in drug delivery for localized and systemic effect. Nanostructured lipid carriers (NLCs) are new generation versatile carriers, which offer protection from degradation and enhance ... -
Formulation of boron encapsulated smart nanocapsules for targeted drug delivery to the brain
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)Drug delivery through the Blood–Brain Barrier (BBB) represents a significant challenge. Despite the current strategies to circumvent the BBB, nanotechnology offers unprecedented opportunities for combining selective delivery, ... -
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
( Elsevier B.V. , 2018 , Article Review)The blood-brain barrier (BBB) plays a crucial role in maintaining brain homeostasis and transport of drugs to the brain. The conventional animal and Transwell BBB models along with emerging microfluidic-based BBB-on-chip ... -
Metal Organic Frameworks, Their Properties and Future Promises in the Medical Field
( Nova Science Publishers, Inc. , 2021 , Book chapter)Nanotechnology is defined as the manipulation of matter at the atomic and molecular level, with nanomedicine being a subdivision of nanotechnology, where nanoparticles are used in medicine often as a drug delivery vehicle ... -
Mucoadhesive chitosan derivatives as novel drug carriers
( Bentham Science Publishers B.V. , 2015 , Article)Chitosan on its own is a well-established natural polymer and is widely regarded as a biodegradable, biocompatible and nontoxic material for drug delivery applications. Although unmodified chitosan has some mucoadhesive ... -
Nanoparticle-based materials in anticancer drug delivery: Current and future prospects
( Elsevier , 2023 , Article Review)The past decade has witnessed a breakthrough in novel strategies to treat cancer. One of the most common cancer treatment modalities is chemotherapy which involves administering anti-cancer drugs to the body. However, these ... -
Nanoparticle-mediated targeted drug delivery for breast cancer treatment
( Elsevier B.V. , 2019 , Article Review)Breast cancer (BC) is the most common malignancy in women worldwide, and one of the deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are surgery followed by chemotherapy or radiotherapy. ... -
Nanoparticles: Attractive tools to treat colorectal cancer
( Elsevier , 2022 , Article)Colorectal Cancer (CRC) is one of the leading causes of cancer-related deaths worldwide. Despite the notable advances achieved over the last few decades, CRC remains a hard-to-treat deadly disease in many patients. This ... -
Novel drug delivery systems based on triaxial electrospinning based nanofibers
( Elsevier B.V. , 2021 , Article)Electrospinning is a widely investigated process for forming nanofibers. Nanofibers in drug delivery systems are extensively tested due to its remarkable properties e.g. small pore size or large surface area. Recent articles ... -
Novel formulation for co-delivery of cinnamon- and cumin-loaded polymeric nanoparticles to enhance their oral bioavailability
( Springer Science and Business Media Deutschland GmbH , 2023 , Article)Nanobiotechnology has been an encouraging approach to improving the efficacy of hydrophobic bioactive compounds. The biologically active constituents present in herbal extracts are poorly absorbed, resulting in loss of ... -
Photo-irradiation paradigm: Mapping a remarkable facile technique used for advanced drug, gene and cell delivery
( Elsevier , 2015 , Article)Undoubtedly, the progression of photo-irradiation technique has provided a smart engineering tool for the state-of-the-art biomaterials that guide the biomedical and therapeutic domains for promoting the modern pharmaceutical ...