Browsing by Subject "Microbiome"

Now showing items 1-9 of 9

    • Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism 

      Korecka, Agata; Dona, Anthony; Lahiri, Shawon; Tett, Adrian James; Al-Asmakh, Maha; ... more authors ( Nature Publishing Group in partnership with Nanyang Technological University , 2016 , Article)
      The ligand-induced transcription factor, aryl hydrocarbon receptor (AhR) is known for its capacity to tune adaptive immunity and xenobiotic metabolism-biological properties subject to regulation by the indigenous microbiome. ...

    • Detection of Paracetamol as substrate of the gut microbiome 

      Mukhtar, Imran; Anwar, Haseeb; Hussain, Ghulam; Rasul, Azhar; Naqvi, Syed Ali Raza; ... more authors ( University of Karachi, Pharmacy College , 2019 , Article)
      Gut microbiome, a new organ; represent targets to alter pharmacokinetics of orally administered drugs. Recently, in vitro trials endorsed the idea that orally administered drugs interact and some of their quantity may be ...

    • Gut microbial communities modulating brain development and function 

      Al-Asmakh, M; Anuar, F; Zadjali, F; Rafter, J; Pettersson, Sven ( Taylor & Francis , 2012 , Article)
      Mammalian brain development is initiated in utero and internal and external environmental signals can affect this process all the way until adulthood. Recent observations suggest that one such external cue is the indigenous ...

    • Impact of physical exercise on gut microbiome, inflammation, and the pathobiology of metabolic disorders 

      Sohail, Muhammad U.; Yassine, Hadi M.; Sohail, Aaqib; Al Thani, Asmaa A. ( Society for Biomedical Diabetes Research , 2019 , Article)
      BACKGROUND: The gastrointestinal tract (GIT) harbors a complex and diverse microbial composition that outnumbers our own body cells and their gene contents. These microbes play a significant role in host metabolism and ...

    • Maternal microbiota regulate glucocorticoids levels and placental development in mice 

      Al-Asmakh, Maha; Hedin, Lars; Pettersson, Sven ( bioscientifica , 2015 , Conference Proceedings)
      The gut microbiota contributes to postnatal development and maturation by influencing barrier functions of the intestinal wall, the development of the immune system, and the utilisation of nutrients. Recent studies have ...

    • Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis. 

      Sohail, Muhammad U; Al Khatib, Hebah A; Al Thani, Asmaa A; Al Ansari, Khalid; Yassine, Hadi M; ... more authors ( BMC , 2021 , Report)
      Rotavirus (RV) is a leading cause of pediatric diarrhea and mortality worldwide. The virus causes acute gastroenteritis characterized by moderate to severe vomiting, diarrhea, dehydration, and fever. Microbial dysbiosis ...

    • Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus. 

      Sohail, Muhammad U; Althani, Asmaa; Anwar, Haseeb; Rizzi, Roberto; Marei, Hany E ( Hindawi Publishing Corporation , 2017 , Article)
      The incidence of diabetes mellitus is rapidly increasing throughout the world. Although the exact cause of the disease is not fully clear, perhaps, genetics, ethnic origin, obesity, age, and lifestyle are considered as few ...

    • THE MICROBIOME AND EPIGENOME PROFILE IN PEDIATRIC TYPE 1 DIABETES IN QATAR 

      Bakhash, Rama Bakhash; Sulaiman, Farzana; Al-Shafai, Mashael; Terranegra, Annalisa ( Qatar University Press , 2020 , Poster)
      This study focused on Qatar's pediatric population that has witnessed a steep increase in the incidence of the disease. In order to understand this, we analyzed the blood and stool samples of a pilot group of 21 T1D subjects ...

    • The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals 

      Singh, Parul; Rawat, Arun; Alwakeel, Mariam; Sharif, Elham; Al Khodor, Souhaila ( Nature Research , 2020 , Article)
      Vitamin D deficiency affects approximately 80% of individuals in some countries and has been linked with gut dysbiosis and inflammation. While the benefits of vitamin D supplementation on the gut microbiota have been studied ...