Browsing by Subject "microRNA"
Now showing items 1-8 of 8
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Exploring the Role of microRNAs in Glioma Progression, Prognosis, and Therapeutic Strategies
( MDPI , 2023 , Article)Gliomas, which arise from glial cells in the brain, remain a significant challenge due to their location and resistance to traditional treatments. Despite research efforts and advancements in healthcare, the incidence of ... -
Glucocorticoid-induced fetal origins of adult hypertension: Association with epigenetic events
( Elsevier Inc. , 2016 , Article Review)Hypertension is a predominant risk factor for cardiovascular diseases and a major health care burden. Accumulating epidemiological and experimental evidence suggest that adult-onset hypertension may have its origins during ... -
Inflammation and hypertension: Underlying mechanisms and emerging understandings
( wiley online library , 2023 , Article Review)Hypertension remains a major contributor to cardiovascular disease (CVD), a leading cause of global death. One of the major insults that drive increased blood pressure is inflammation. While it is the body's defensive ... -
An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study
( Springer Nature , 2023 , Article)Objectives: To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways. Methods: We analyzed a cohort of 39 ... -
MicroRNA-mediated regulation of LDL receptor: biological and pharmacological implications.
( Europe PM , 2023 , Article)One of the main causes of atherosclerosis is a disruption in cellular cholesterol hemostasis. The low-density lipoprotein receptor (LDLR) is an important factor in maintaining cholesterol homeostasis by the receptor-mediated ... -
MicroRNAs as Potential Pharmaco-targets in Ischemia-Reperfusion Injury Compounded by Diabetes.
( MDPI , 2019 , Article)Ischemia-Reperfusion (I/R) injury is the tissue damage that results from re-oxygenation of ischemic tissues. There are many players that contribute to I/R injury. One of these factors is the family of microRNAs (miRNAs), ... -
miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes.
( Wiley , 2019 , Article)This study aimed to analyze the potential association of different microRNA (miRNA) molecules with both type 2 diabetes (T2D) and obesity and determine their target genes. Quantitative PCR was used to analyze the miR-20b, ... -
Novel Epigenetic Biomarkers in Pregnancy-Related Disorders and Cancers
( MDPI , 2019 , Article)As the majority of cancers and gestational diseases are prognostically stage- and grade-dependent, the ultimate goal of ongoing studies in precision medicine is to provide early and timely diagnosis of such disorders. These ...