• Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar 

      Ismail, Mohamed A; Samara, Muthanna; Al Sayab, Ali; Alsharshani, Mohamed; Yassin, Mohamed A; ... more authors ( Wiley Open Access , 2020 , Article)
      Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ...
    • Anticancer potential of sanguinarine for various human malignancies 

      Achkar, Iman W; Mraiche, Fatima; Mohammad, Ramzi M; Uddin, Shahab ( Future Medicine Ltd. , 2017 , Article Review)
      Sanguinarine (Sang) - a benzophenanthridine alkaloid extracted from Sanguinaria canadensis - exhibits antioxidant, anti-inflammatory, proapoptotic and growth inhibitory activities on tumor cells of various cancer types as ...
    • Anticancer Potential of the Cyclolinopeptides 

      Fojnica, Adnan; Gromilic, Zehra; Vranic, Semir; Murkovic, Michael ( MDPI , 2023 , Article Review)
      Novel therapeutic agents to combat cancer is an active area of research, as current treatment options have limitations in efficacy and tolerability. One of these therapeutic agents in our immediate environment is ...
    • Assessment of Dasatinib Versus Nilotinib as Upfront Therapy for Chronic Phase of Chronic Myeloid Leukemia in Qatar: A Cost-Effectiveness Analysis 

      Adel, A.; Abushanab, D.; Hamad, A.; Abdulla, M.; Izham, Mohamed; ... more authors ( SAGE Publications Ltd , 2021 , Article)
      Background: The economic outcome research of approved tyrosine kinase inhibitors for treating the chronic phase of chronic myeloid leukemia in developing is scarce. The aim of this study was to assess the cost-effectiveness ...
    • Association of Serum 25-Hydroxyvitamin D Concentration with Breast Cancer Risk in Postmenopausal Women in the US 

      Ganji, Vijay; Sukik, Layan; Hoque, Bushra; Boutefnouchet, Linda; Shi, Zumin ( MDPI , 2022 , Article)
      The association between serum 25-hydroxyvitamin D [25(OH)D] concentration and breast cancer risk in postmenopausal women is not well understood. The aim of this study was to investigate the association between serum ...
    • Automated Detection of Brain Tumor through Magnetic Resonance Images Using Convolutional Neural Network 

      Gull, Sahar; Akbar, Shahzad; Khan, Habib Ullah ( Hindawi , 2021 , Article)
      Brain tumor is a fatal disease, caused by the growth of abnormal cells in the brain tissues. Therefore, early and accurate detection of this disease can save patient's life. This paper proposes a novel framework for the ...
    • Biological applications of imiquimod analogues: An update (Review) 

      Obeid, Joelle; Shaito, Abdullah; Hajj, Hiba El; Deleuze-Masquefa, Carine; Bonnet, Pierre Antoine; ... more authors ( Spandidos Publications , 2023 , Article Review)
      The last decade witnessed intensive efforts in drug discovery and the emergence of thousands of molecules with potential for use as therapeutic targets. However, only a few hundred of these molecules reached the stage of ...
    • Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019: A Systematic Analysis for the Global Burden of Disease Study 2019. 

      Harvey, James D; Henrikson, Hannah Jacqueline; Lu, Dan; Pennini, Alyssa; Xu, Rixing; ... more authors ( American Medical Association , 2021 , Article)
      The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. ...
    • Characteristics of the clinical pharmacist interventions at the National Center for Cancer Care and Research Hospital in Qatar 

      Al Dali, Sara; Al-Badriyeh, Daoud; Gulied, Amaal; Hamad, Anas; Hail, Moza Al; ... more authors ( SAGE Publications Ltd , 2023 , Article)
      Introduction Drug-related problems (DRPs) affect the health outcomes of patients during hospitalization. We sought to analyze the clinical pharmacist-documented interventions among hospitalized patients in the cancer ...
    • Chronic kidney diseases and the risk of colorectal cancer: A systematic review and meta-analysis 

      Al-Qudimat, Ahmad R.; Al Darwish, Mohamed B.; Altahtamouni, Saif B.; Singh, Kalapan; Al-Zoubi, Raed M.; ... more authors ( Taylor and Francis Ltd. , 2023 , Article)
      Objective: We conducted this review to offer a comprehensive search and up-to-date overview of the currently available information about the probability risk of colorectal cancer among chronic kidney disease patients. ...
    • Clinical significance of P-class pumps in cancer (Review) 

      Themistocleous, Sophia C.; Yiallouris, Andreas; Tsioutis, Constantinos; Zaravinos, Apostolos; Johnson, Elizabeth O.; ... more authors ( Spandidos Publications , 2021 , Article)
      P-class pumps are specific ion transporters involved in maintaining intracellular/extracellular ion homeostasis, gene transcription, and cell proliferation and migration in all eukaryotic cells. The present review aimed ...
    • Cost savings and cost avoidance with the inpatient clinical pharmacist interventions in a tertiary cancer care hospital 

      Abushanab, Dina; Gulied, Amaal; Hamad, Anas; Abu-Tineh, Mohammad; Abdul Rouf, Palli V.; ... more authors ( SAGE , 2023 , Article)
      Background: The economic benefit of the clinical pharmacist's role in ensuring the optimum use of medicines is potentially considerable, particularly when it comes to cancer management. We sought to evaluate the overall ...
    • Critical appraisal of clinical practice guidelines for adult cancer patients with febrile neutropenia 

      Nasr Z.G.; Abu Yousef S.; Jibril F.; Wilby K.J. ( Wiley-Blackwell Publishing Ltd , 2018 , Article)
      Objectives: To critically appraise published international clinical practice guidelines (CPGs) for management of febrile neutropenia in adult patients with cancer and to determine opportunities for improved development and ...
    • Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach 

      Adhikary, Subhamay; Pathak, Surajit; Palani, Vignesh; Acar, Ahmet; Banerjee, Antara; ... more authors ( MDPI , 2024 , Article Review)
      Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...
    • Dietary Intake Is Not Associated with Body Composition nor with Biochemical Tests but with Psychological Status of Cancer Patients Receiving Chemotherapy 

      Subih, Hadil S.; Al-Shwaiyat, Esraa A.; Al-Bayyari, Nahla; Obeidat, Belal S.; Abu-Farsakh, Fadi; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)
      Chemotherapy can negatively affect cancer patients’ eating patterns, psychological status, body composition, and quality of life. In this study, we aimed to investigate the correlations between dietary intake/care and the ...
    • Direct Oral Anticoagulant Use in Atypical Thrombosis-Related Conditions 

      Chang C.; Hoyos M.; Owusu Y.; Elewa H. ( SAGE Publications Inc. , 2018 , Article Review)
      Objective: To review the published literature for evidence of the efficacy and safety of direct oral anticoagulants (DOACs) when used in the management of atypical thrombosis-related conditions. Data Sources: A comprehensive ...
    • Disease-Associated Regulation of Non-Coding RNAs by Resveratrol: Molecular Insights and Therapeutic Applications 

      Giordo,Roberta; Wehbe,Zena; Posadino,Anna Maria; Erre,Gian Luca; Eid,Ali H.; ... more authors ( Frontiers Media S.A. , 2022 , Article Review)
      There have been significant advances, particularly over the last 20 years, in the identification of non-coding RNAs (ncRNAs) and their pathophysiological role in a wide range of disease states, particularly cancer and other ...
    • Editorial: Anti-cancer drug delivery: lipid-based nanoparticles 

      Alkilany,Alaaldin M.; Elhissi,Abdelbary; Alshaer,Walhan; Kunwar,Amit; Giri,Jyotsnendu ( Frontiers Media SA , 2023 , Other)
      Cancer continues to pose significant challenges that require extensive attention and efforts from the scientific community. The battle against cancer encompasses the development of effective and safe therapeutic approaches. ...
    • Effectiveness of Aromatherapy in Early Palliative Care for Oncology Patients: Blind Controlled Study 

      Khamis, Engy Abdel Rhman; Abu Raddaha, Ahmad H.; Nafae, Waleed Hamdy; Al-Sabeely, Amirat A.; Ebrahim, Elturabi E.; ... more authors ( West Asia Organization for Cancer Prevention (WAOCP), APOCP's West Asia Chapter. , 2023 , Article)
      Background: Palliative care is the active holistic treatment of people of all ages who have serious health-related suffering as a result of severe illness, and especially of those who are close to the end of life. Palliative ...