Browsing by Subject "cell differentiation"
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Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
( Elsevier B.V. , 2021 , Article)Alzheimer's disease (AD) is the major cause of dementia worldwide. Early-onset familial AD accounts for about 0.5% of all AD and is caused by single major gene mutations and autosomal dominant inheritance. An N141I missense ... -
Myocardial ischemic subject's thymus fat: A novel source of multipotent stromal cells
( Public Library of Science , 2015 , Article)Objective Adipose Tissue Stromal Cells (ASCs) have important clinical applications in the regenerative medicine, cell replacement and gene therapies. Subcutaneous Adipose Tissue (SAT) is the most common source of these ...