Browsing by Subject "cholesterol"

Now showing items 1-6 of 6

    • Comparative efficacy and safety among high-intensity statins. Systematic Review and Meta-Analysis 

      Jaam, Myriam; Al-Naimi, Hend Nasser; Haddad, Moumena Mahmoud; Abushanab, Dina; Al-Badriyeh, Daoud ( Becaris Publishing , 2023 , Article)
      Aim: To summarize the evidence in terms of efficacy and safety of head-to-head studies of high-intensity statins regardless of the underlying population. Materials & methods: A systematic review and meta-analysis was ...

    • Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes 

      Patel, J. P.; Hamdy, D. A.; El-kadi, A. O.; Brocks, D. R. ( John Wiley & Sons, Ltd , 2012 , Article)
      Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. The present study examined the ...

    • Effect of Silymarin Treatment on Circulating Bilirubin and Cardiovascular Disease Risk Factors in Healthy Men: A Single-Blind, Randomized Crossover Trial 

      Vidimce, Josif; Pennell, Evan Noel; Foo, Maxmilian; Shiels, Ryan Graeme; Shibeeb, Sapha; ... more authors ( Wiley , 2021 , Article)
      This clinical trial (ACTRN12619001296123) investigated the impact of silymarin (Legalon®) on circulating bilirubin concentration, lipid status, systemic inflammation, and antioxidant status. The study design was a randomized, ...

    • Fat intake and the risk of coronary heart disease among Jordanians 

      Tayyem, Reema F.; Al-Shudifat, Abdel-Ellah; Hammad, Shatha; Agraib, Lana M.; Azab, Mohammed; ... more authors ( Aula Médica Ediciones , 2020 , Article)
      Introduction: dietary fat has been reported as one of the significant risk factors in the development of cardiovascular diseases (CVD). Objective: this study aimed at assessing the possible association between fat intake ...

    • Rare coding variants in 35 genes associate with circulating lipid levels—A multi-ancestry analysis of 170,000 exomes 

      George, Hindy; Dornbos, Peter; Chaffin, Mark D.; Liu, Dajiang J.; Wang, Minxian; ... more authors ( Elsevier , 2022 , Article)
      Large-scale gene sequencing studies for complex traits have the potential to identify causal genes with therapeutic implications. We performed gene-based association testing of blood lipid levels with rare (minor allele ...

    • Statins Formulary Selection in Qatar, Based on Multi-Indication Pharmacotherapeutic Multi-Criteria Scoring, and Clinician Preference 

      Al-Badriyeh, Daoud; Fahey, Michael; Fahey, Michael; Alabbadi, Ibrahim; Fahey, Michael; ... more authors ( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)
      Purpose: Statins selection for the largest hospital formulary in Qatar is not systematic, not comparative, not cost saving, and does not consider the multi-indication nature of statins. There are no literature reports of ...