Time-frequency Analysis of Heart Rate Variability for Neonatal Seizure Detection

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Time-frequency Analysis of Heart Rate Variability for Neonatal Seizure Detection

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Title: Time-frequency Analysis of Heart Rate Variability for Neonatal Seizure Detection
Author: Malarvili, M.B.; Mesbah, M; Boashash, B
Abstract: The ECG has been much neglected in automatic seizure detection in the newborn. Changes in heart rate and ECG rhythm are often found in animal and adult patients with seizure. However, little is known about heart rate variability (HRV) changes in human neonate during seizure. Results of ongoing time-frequency research are presented here with the aim to compare the performance of various time-frequency distributions (TFDs) when applied to HRV time series for non-seizure and seizure newborns. The TFDs studied are the Wigner-Ville (WVD), the Spectrogram (SP), the Choi-Williams (CWD) and the Modified B (MBD) distributions. Based on our preliminary results, our current conclusion is MBD outperforms other TFDs in terms of time-frequency resolution, cross-terms suppression and to represent the newborn HRV signals of non-seizure and seizure which are closely-spaced components in the time-frequency domain.
Description: This paper shows that the MBD is the most suitable TFD for characterizing the property of HRV for neonatal seizure detection as itoutperforms other existing distributions in terms of time-frequency resolution, as well as cross-terms suppression and can represent the HRV signals which are closely-spaced components in the time-frequency domain. (Additional details can be found in the comprehensive book on Time-Frequency Signal Analysis and Processing (see http://www.elsevier.com/locate/isbn/0080443354). In addition, the most recent upgrade of the original software package that calculates Time-Frequency Distributions and Instantaneous Frequency estimators can be downloaded from the web site: www.time-frequency.net. This was the first software developed in the field, and it was first released publicly in 1987 at the 1st ISSPA conference held in Brisbane, Australia, and then continuously updated)
URI: http://hdl.handle.net/10576/10765
Date: 2006-03

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