Browsing by Author "Simons, Keith J."
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Epinephrine in anaphylaxis: Preclinical study of pharmacokinetics after sublingual administration of taste-masked tablets for potential pediatric use
Rachid, Ousama; Rawas-Qalaji, Mutasem; Simons, Keith J. ( MDPI AG , 2018 , Article)Epinephrine is a life-saving treatment in anaphylaxis. In community settings, a first-aid dose of epinephrine is injected from an auto-injector (EAI). Needle phobia highly contributes to EAI underuse, leading to ... -
In Vivo Evaluation of Taste-Masked Fast-Disintegrating Sublingual Tablets of Epinephrine Microcrystals
Rachid, Ousama; Simons, Keith J.; Rawas-Qalaji, Mutasem ( Springer New York LLC , 2018 , Article)n community settings, IM injection of 0.3 mg epinephrine (Epi) using an auto-injector is the drug of choice for treatment of anaphylaxis. Previously, a taste-masking (TM) formulation of fast-disintegrating sublingual tablets ...