Browsing by Author "Agouni, Abdelali"
Now showing items 41-52 of 52
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The relationship between bone mineral density and body composition among Qatari women with high rate of obesity: qatar Biobank Data
Kerkadi, Abdelhamid; Lathief, Shalima; Khial, Yasmen; Teleb, Toka; Attieh, Grace; Rahman, Md Mizanur; Shi, Zumin; Agouni, Abdelali... more authors ... less authors ( Frontiers Media , 2022 , Article)Studies have reported inconsistent results for the relationship between body composition and bone mineral density (BMD) among women, especially those with a high rate of obesity. This study aims to examine the association ... -
The Role of Protein Tyrosine Phosphatase (PTP)-1B in Cardiovascular Disease and Its Interplay with Insulin Resistance.
Abdelsalam, Shahenda S; Korashy, Hesham M; Zeidan, Asad; Agouni, Abdelali ( MDPI , 2019 , Article Review)Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ... -
Selenium and Health: An Update on the Situation in the Middle East and North Africa.
Ibrahim, Sohayla A Z; Kerkadi, Abdelhamid; Agouni, Abdelali ( MDPI , 2019 , Article)Selenium (Se) is an important trace element that should be present in the diet of all age groups to provide an adequate intake. Se is incorporated in 25 known selenoproteins, which mediate the biological effects of Se ... -
Sestrin2 as a Protective Shield against Cardiovascular Disease
Zahid, Muhammad Ammar; Abdelsalam, Shahenda Salaheldin; Raïq, Hicham; Parray, Aijaz; Korashy, Hesham Mohamed; Zeidan, Asad; Elrayess, Mohamed A.; Agouni, Abdelali... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)A timely and adequate response to stress is inherently present in each cell and is important for maintaining the proper functioning of the cell in changing intracellular and extracellular environments. Disruptions in the ... -
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
Fatima, Munazza T; Hasan, Maram; Abdelsalam, Shahenda S; Sivaraman, Siveen K; El-Gamal, Heba; Zahid, Muhammad A; Elrayess, Mohamed A; Korashy, Hesham M; Zeidan, Asad; Parray, Aijaz S; Agouni, Abdelali... more authors ... less authors ( Elsevier , 2021 , Article)Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ... -
Suppression of GATA-3 increases adipogenesis, reduces inflammation and improves insulin sensitivity in 3T3L-1 preadipocytes
Al-Mansoori, Layla; Al-Jaber, Hend; Madani, Aisha Y.; Mazloum, Nayef A.; Agouni, Abdelali; Ramanjaneya, Manjunath; Abou-Samra, Abdul Badi; Elrayess, Mohamed A.... more authors ... less authors ( Elsevier , 2020 , Article)© 2020 Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. GATA-3 plays important ... -
Temporal cross talk between endoplasmic reticulum and mitochondria regulates oxidative stress and mediates microparticle-induced endothelial dysfunction
Safiedeen, Zainab; Rodríguez-Gómez, Isabel; Vergori, Luisa; Soleti, Raffaella; Vaithilingam, Dayannath; Douma, Imene; Agouni, Abdelali; Leiber, Denis; Dubois, Séverine; Simard, Gilles; Zibara, Kazem; Andriantsitohaina, Ramaroson; Martínez, M. Carmen... more authors ... less authors ( Mary Ann Liebert, Inc. , 2017 , Article)Aims: Circulating microparticles (MPs) from metabolic syndrome patients and those generated from apoptotic T-cells induce endothelial dysfunction; however, the molecular and cellular mechanism(s) underlying in the effects ... -
The Association between Zinc and Copper and Cardiometabolic Risk Factors in Adults
Al Kudsi, Dana Samir; Hamad, Sara Zeyad; Al Keldi, Hanan Mohamed; Kerkadi, Abdelhamid; Agouni, Abdelali; Salih, Reem Omar... more authors ... less authors ( Qatar University Press , 2021 , Poster)Cardiometabolic risk (CMR) factors increase the likelihood of developing cardiovascular diseases (CVD). In Qatar, 24% of the total deaths are attributed to CVDs. Several nutritional disturbances have been linked to high ... -
The protective role of Sestrin2 in high fat diet-induced nephropathy
Agouni, Abdelali; Lee, Duck Y; Eid, Assaad A; Gorin, Yves; Sharma, Kumar ( Qatar University Press , 2020 , Poster)Introduction: Obesity is a major risk factor for type-2 diabetes predisposing patients to diabetic nephropathy (DN), the leading cause of end-stage renal failure. Glomerular injury is a prominent pathological feature of ... -
The role of protein tyrosine phosphatase (PTP)-1B in cardiovascular disease and its interplay with insulin resistance
Abdelsalam, Shahenda S.; Korashy, Hesham M.; Zeidan, Asad; Agouni, Abdelali ( MDPI AG , 2019 , Article Review)Endothelial dysfunction is a key feature of cardiovascular disorders associated with obesity and diabetes. Several studies identified protein tyrosine phosphatase (PTP)-1B, a member of the PTP superfamily, as a major ... -
There Is Selective Increase in Pro-thrombotic Circulating Extracellular Vesicles in Acute Ischemic Stroke and Transient Ischemic Attack: A Study of Patients From the Middle East and Southeast Asia.
Agouni, Abdelali; Parray, Aijaz S; Akhtar, Naveed; Mir, Fayaz A; Bourke, Paula J; Joseph, Sujata; Morgan, Deborah M; Santos, Mark D; Wadiwala, Muhammad F; Kamran, Saadat; Sivaraman, Siveen K; Shuaib, Ashfaq... more authors ... less authors ( Frontiers Media , 2019 , Article)Stroke attacks were found to be present at a younger age in patients from Southeast Asia (SE) and the Middle East (ME) resident in the state of Qatar. Extracellular vesicles (EVs), which are small membrane vesicles with ... -
Using Assessment Design Decision Framework in understanding the impact of rapid transition to remote education on student assessment in health-related colleges: A qualitative study.
Jaam, Myriam; Nazar, Zachariah; Rainkie, Daniel C; Hassan, Diana Alsayed; Hussain, Farhat Naz; Kassab, Salah Eldin; Agouni, Abdelali... more authors ... less authors ( Public Library of Science , 2021 , Article)Maintaining integrity and validity with online assessment is a significant issue that is well documented. Overt policies encouraging educators to adopt e-Learning and implement digital services coupled with the dramatic ...