• Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Nature Research , 2022 , Article)
      There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...
    • SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines 

      Zedan, Hadeel T.; Smatti, Maria K.; Al-Sadeq, Duaa W.; Al Khatib, Hebah A.; Nicolai, Eleonora; ... more authors ( Wiley , 2024 , Article)
      Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ...
    • Use of Hemagglutinin Stem Probes Demonstrate Prevalence of Broadly Reactive Group 1 Influenza Antibodies in Human Sera. 

      Yassine, Hadi M; McTamney, Patrick M; Boyington, Jeffery C; Ruckwardt, Tracy J; Crank, Michelle C; ... more authors ( Nature Publishing Group , 2018 , Article)
      A better understanding of the seroprevalence and specificity of influenza HA stem-directed broadly neutralizing antibodies (bNAbs) in the human population could significantly inform influenza vaccine design efforts. Here, ...
    • Vaccine evaluation and genotype characterization in children infected with rotavirus in Qatar 

      Mathew, Shilu; Al Khatib, Hebah A.; Al Ibrahim, Malak; Al Ansari, Khalid; Smatti, Maria K.; ... more authors ( Springer Nature , 2023 , Article)
      Background: We characterized and identified the genetic and antigenic variations of circulating rotavirus strains in comparison to used rotavirus vaccines. Methods: Rotavirus-positive samples (n = 231) were collected and ...
    • Viral meningitis : an overview 

      Kohil, Amira; Jemmieh, Sara; Smatti, Maria K; Yassine, Hadi M ( Springer-Verlag , 2021 , Article)
      Meningitis is a serious condition that affects the central nervous system. It is an inflammation of the meninges, which is the membrane that surrounds both the brain and the spinal cord. Meningitis can be caused by bacterial, ...
    • Viral-Induced Enhanced Disease Illness 

      Smatti, Maria K; Al Thani, Asmaa A; Yassine, Hadi M ( Frontiers Media , 2018 , Article)
      Understanding immune responses to viral infections is crucial to progress in the quest for effective infection prevention and control. The host immunity involves various mechanisms to combat viral infections. Under certain ...
    • Viruses and Autoimmunity: A Review on the Potential Interaction and Molecular Mechanisms. 

      Smatti, Maria K; Cyprian, Farhan S; Nasrallah, Gheyath K; Al Thani, Asmaa A; Almishal, Ruba O; ... more authors ( MDPI , 2019 , Article)
      For a long time, viruses have been shown to modify the clinical picture of several autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren's syndrome ...
    • Will Host Genetics Affect the Response to SARS-CoV-2 Vaccines? Historical Precedents 

      Smatti, Maria K.; Alkhatib, Hebah A.; Al Thani, Asmaa A.; Yassine, Hadi M. ( Frontiers Media , 2022 , Article Review)
      Recent progress in genomics and bioinformatics technologies have allowed for the emergence of immunogenomics field. This intersection of immunology and genetics has broadened our understanding of how the immune system ...
    • Will influenza A(H3N8) cause a major public health threat? 

      Hadi M., Yassine; Smatti, Maria K. ( Elsevier , 2022 , Other)
      The diversity of zoonotic influenza viruses and their ability to cross the species barrier has always been alarming and requires continuous surveillance in both human and animal populations. Avian A(H3N8) influenza viruses ...