• A High-Realism and Cost-Effective Training Simulator for Extracorporeal Membrane Oxygenation 

      Alsalemi, Abdullah; Alhomsi, Yahya; Bensaali, Faycal; Hssain, Ali Ait ( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)
      Medical simulators, employed in extracorporeal membrane oxygenation (ECMO), are burdened with costly equipment and low-fidelity methodologies. This dichotomy necessitated a new approach that eliminates high-costs and ...
    • Assessing Learning Outcomes in Extracorporeal Membrane Oxygenation Simulations with a Novel Simulator and Instructor Application 

      Alsalemi, Abdullah; Alhomsi, Yahya; Bensaali, Faycal; Alinier, Guillaume; Hssain, Ali Ait ( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)
      Simulation plays an important part in enhancing the outcomes of clinical training worldwide. In particular, extracorporeal membrane oxygenation (ECMO) is a life-saving procedure that utilizes a cardiopulmonary bypass circuit ...
    • Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination 

      Zedan, Hadeel T.; Smatti, Maria K.; Thomas, Swapna; Nasrallah, Gheyath K.; Afifi, Nahla M.; ... more authors ( American Medical Association , 2023 , Article)
      Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ...
    • Association between periodontitis and severity of COVID-19 infection: A case–control study 

      Marouf, Nadya; Cai, Wenji; Said, Khalid N.; Daas, Hanin; Diab, Hanan; ... more authors ( Wiley , 2021 , Article)
      Aim: COVID-19 is associated with an exacerbated inflammatory response that can result in fatal outcomes. Systemic inflammation is also a main characteristic of periodontitis. Therefore, we investigated the association of ...
    • Association of periodontal therapy, with inflammatory biomarkers and complications in COVID-19 patients: a case control study 

      Said, Khalid N.; Al-Momani, Ahmed M.; Almaseeh, Jassim A.; Marouf, Nadya; Shatta, Amer; ... more authors ( Springer , 2022 , Article)
      Background: In previous studies, COVID-19 complications were reported to be associated with periodontitis. Accordingly, this study was designed to test the hypothesis that a history of periodontal therapy could be associated ...
    • Cost-Effectiveness Analysis of Out-Of-Hospital versus In-Hospital Extracorporeal Cardiopulmonary Resuscitation for Out-Hospital Refractory Cardiac Arrest 

      Al-Badriyeh, Daoud; Hssain, Ali Ait; Abushanab, Dina ( Elsevier , 2022 , Article)
      It has been speculated that out-of-hospital cardiac arrest (OHCA) patients’ survival might be improved by implementing extracorporeal cardiopulmonary resuscitation (ECPR) before arrival to hospital. Therefore, we sought ...
    • Development of an in-house COVID-19 serology ELISA Test 

      Chowdhury, Shazeda; Taleb, Sara; Elgamal, Mahmoud; Hassan, Nesyia; Nomikos, Michail; ... more authors ( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)
      Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within ...
    • Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines 

      Fernandes, Queenie; Inchakalody, Varghese Philipose; Merhi, Maysaloun; Mestiri, Sarra; Taib, Nassiba; ... more authors ( Taylor and Francis , 2022 , Article)
      The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing ...
    • High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines 

      Rinchai, Darawan; Deola, Sara; Zoppoli, Gabriele; Kabeer, Basirudeen Syed Ahamed; Taleb, Sara; ... more authors ( American Association for the Advancement of Science , 2022 , Article)
      Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ...
    • IoT-based mock oxygenator for extracorporeal membrane oxygenation simulator 

      Sayed, Aya; Alhomsi, Yahya; Alsalemi, Abdullah; Bensaali, Faycal; Meskin, Nader; ... more authors ( John Wiley and Sons Inc , 2022 , Article)
      Background: Training is an essential aspect of providing high-quality treatment and ensuring patient safety in any medical practice. Because extracorporeal membrane oxygenation (ECMO) is a complicated operation with various ...
    • Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies 

      Hadi M., Yassine; Al-Jighefee, Hadeel; Al-Sadeq, Duaa W.; Dargham, Soha R.; Younes, Salma N.; ... more authors ( Elsevier , 2020 , Article)
      ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ...
    • Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study 

      Mestiri, Sarra; Merhi, Maysaloun; Inchakalody, Varghese P.; Taib, Nassiba; Smatti, Maria K.; ... more authors ( Frontiers Media , 2023 , Article)
      Introduction: The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods: ...
    • Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications 

      Al-Nesf, Maryam A. Y.; Abdesselem, Houari B.; Bensmail, Ilham; Ibrahim, Shahd; Saeed, Walaa A. H.; ... more authors ( Nature Research , 2022 , Article)
      COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ...
    • A Prospective Cohort Study (OUTSTRIP-COVID) on Functional and Spirometry Outcomes in COVID-19 ICU Survivors at 3 Months 

      Thomas, Merlin; Raza, Tasleem; Hameed, Mansoor; Sharma, Rohit; Rajagopal, Rajalekshmi Maheswari; ... more authors ( Taylor & Francis Group , 2023 , Article)
      Purpose: COVID-19 pandemic resulted in a significant number of critical care admissions secondary to severe pneumonia and acute respiratory distress syndrome. We evaluated the short-, medium-and long-term outcomes of lung ...
    • Towards next generation cannulation simulators 

      Mahmoud, Abdulrahman; Khurshid, Uzair; Abducarim, Aiman; Mahmud, Sakib; Abdallah, Omrane; ... more authors ( Hamad bin Khalifa University Press (HBKU Press) , 2020 , Article)
      Background: Cannulation, in extracorporeal membrane oxygenation (ECMO), is the act of inserting a cannula through the body1. For femoral veins, femoral arteries, and the jugular vein, the cannula stops at the inferior vena ...