Browsing by Author "Hssain, Ali Ait"
Now showing items 1-15 of 15
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A High-Realism and Cost-Effective Training Simulator for Extracorporeal Membrane Oxygenation
Alsalemi, Abdullah; Alhomsi, Yahya; Bensaali, Faycal; Hssain, Ali Ait ( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)Medical simulators, employed in extracorporeal membrane oxygenation (ECMO), are burdened with costly equipment and low-fidelity methodologies. This dichotomy necessitated a new approach that eliminates high-costs and ... -
Assessing Learning Outcomes in Extracorporeal Membrane Oxygenation Simulations with a Novel Simulator and Instructor Application
Alsalemi, Abdullah; Alhomsi, Yahya; Bensaali, Faycal; Alinier, Guillaume; Hssain, Ali Ait ( Institute of Electrical and Electronics Engineers Inc. , 2021 , Article)Simulation plays an important part in enhancing the outcomes of clinical training worldwide. In particular, extracorporeal membrane oxygenation (ECMO) is a life-saving procedure that utilizes a cardiopulmonary bypass circuit ... -
Assessment of Broadly Reactive Responses in Patients With MERS-CoV Infection and SARS-CoV-2 Vaccination
Zedan, Hadeel T.; Smatti, Maria K.; Thomas, Swapna; Nasrallah, Gheyath K.; Afifi, Nahla M.; Hssain, Ali Ait; Abu Raddad, Laith J.; Coyle, Peter V.; Grivel, Jean Charles; Almaslamani, Muna A.; Althani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( American Medical Association , 2023 , Article)Importance: In the ongoing COVID-19 pandemic, there remain unanswered questions regarding the nature and importance of the humoral immune response against other coronaviruses. Although coinfection of the Middle East ... -
Association between periodontitis and severity of COVID-19 infection: A case–control study
Marouf, Nadya; Cai, Wenji; Said, Khalid N.; Daas, Hanin; Diab, Hanan; Chinta, Venkateswara Rao; Hssain, Ali Ait; Nicolau, Belinda; Sanz, Mariano; Tamimi, Faleh... more authors ... less authors ( Wiley , 2021 , Article)Aim: COVID-19 is associated with an exacerbated inflammatory response that can result in fatal outcomes. Systemic inflammation is also a main characteristic of periodontitis. Therefore, we investigated the association of ... -
Association of periodontal therapy, with inflammatory biomarkers and complications in COVID-19 patients: a case control study
Said, Khalid N.; Al-Momani, Ahmed M.; Almaseeh, Jassim A.; Marouf, Nadya; Shatta, Amer; Al-Abdulla, Jassim; Alaji, Sahar; Daas, Hanin; Tharupeedikayil, Shailaja S.; Chinta, Venkateswara Rao; Hssain, Ali Ait; Abusamak, Mohammad; Salih, Shiraz; Barhom, Noha; Cai, Wenji; Sanz, Mariano; Tamimi, Faleh... more authors ... less authors ( Springer , 2022 , Article)Background: In previous studies, COVID-19 complications were reported to be associated with periodontitis. Accordingly, this study was designed to test the hypothesis that a history of periodontal therapy could be associated ... -
Cost-Effectiveness Analysis of Out-Of-Hospital versus In-Hospital Extracorporeal Cardiopulmonary Resuscitation for Out-Hospital Refractory Cardiac Arrest
Al-Badriyeh, Daoud; Hssain, Ali Ait; Abushanab, Dina ( Elsevier , 2022 , Article)It has been speculated that out-of-hospital cardiac arrest (OHCA) patients’ survival might be improved by implementing extracorporeal cardiopulmonary resuscitation (ECPR) before arrival to hospital. Therefore, we sought ... -
Development of an in-house COVID-19 serology ELISA Test
Chowdhury, Shazeda; Taleb, Sara; Elgamal, Mahmoud; Hassan, Nesyia; Nomikos, Michail; Hssain, Ali Ait; Zughaier, Susu M... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2021 , Article)Background: COVID-19 pandemic created an unprecedented demand for reagents and diagnostic tools to confirm COVID-19 cases. Thus, the development of a robust in-house diagnostic test is considered of high importance. Within ... -
Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
Fernandes, Queenie; Inchakalody, Varghese Philipose; Merhi, Maysaloun; Mestiri, Sarra; Taib, Nassiba; Moustafa Abo El-Ella, Dina; Bedhiafi, Takwa; Raza, Afsheen; Al-Zaidan, Lobna; Mohsen, Mona O.; Yousuf Al-Nesf, Mariam Ali; Hssain, Ali Ait; Yassine, Hadi Mohamad; Bachmann, Martin F.; Uddin, Shahab; Dermime, Said... more authors ... less authors ( Taylor and Francis , 2022 , Article)The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing ... -
High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines
Rinchai, Darawan; Deola, Sara; Zoppoli, Gabriele; Kabeer, Basirudeen Syed Ahamed; Taleb, Sara; Pavlovski, Igor; Maacha, Selma; Gentilcore, Giusy; Toufiq, Mohammed; Mathew, Lisa; Liu, Li; Vempalli, Fazulur Rehaman; Mubarak, Ghada; Lorenz, Stephan; Sivieri, Irene; Cirmena, Gabriella; Dentone, Chiara; Cuccarolo, Paola; Giacobbe, Daniele Roberto; Baldi, Federico; Garbarino, Alberto; Cigolini, Benedetta; Cremonesi, Paolo; Bedognetti, Michele; Ballestrero, Alberto; Bassetti, Matteo; Hejblum, Boris P.; Augustine, Tracy; Van Panhuys, Nicholas; Thiebaut, Rodolphe; Branco, Ricardo; Chew, Tracey; Shojaei, Maryam; Short, Kirsty; Feng, Carl G.; Zughaier, Susu M.; De Maria, Andrea; Tang, Benjamin; Hssain, Ali Ait; Bedognetti, Davide; Grivel, Jean Charles; Chaussabel, Damien... more authors ... less authors ( American Association for the Advancement of Science , 2022 , Article)Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ... -
IoT-based mock oxygenator for extracorporeal membrane oxygenation simulator
Sayed, Aya; Alhomsi, Yahya; Alsalemi, Abdullah; Bensaali, Faycal; Meskin, Nader; Hssain, Ali Ait... more authors ... less authors ( John Wiley and Sons Inc , 2022 , Article)Background: Training is an essential aspect of providing high-quality treatment and ensuring patient safety in any medical practice. Because extracorporeal membrane oxygenation (ECMO) is a complicated operation with various ... -
Performance evaluation of five ELISA kits for detecting anti-SARS-COV-2 IgG antibodies
Hadi M., Yassine; Al-Jighefee, Hadeel; Al-Sadeq, Duaa W.; Dargham, Soha R.; Younes, Salma N.; Shurrab, Farah; Marei, Reham M.; Hssain, Ali Ait; Taleb, Sara; Alhussain, Hashim A.; Al-Nesf, Maryiam A.; Al-Khal, Abdullatif; Qotba, Hamda; Althani, Asmaa A.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( Elsevier , 2020 , Article)ObjectivesTo evaluate and compare the performances of five commercial ELISA assays (EDI, AnshLabs, Dia.Pro, NovaTec, and Lionex) for detecting anti-SARS-CoV-2 IgG. Methods70 negative control samples (collected before the ... -
Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Mestiri, Sarra; Merhi, Maysaloun; Inchakalody, Varghese P.; Taib, Nassiba; Smatti, Maria K.; Ahmad, Fareed; Raza, Afsheen; Ali, Fatma H.; Hydrose, Shereena; Fernandes, Queenie; Ansari, Abdul W.; Sahir, Fairooz; Al-Zaidan, Lobna; Jalis, Munir; Ghoul, Mokhtar; Allahverdi, Niloofar; Al Homsi, Mohammed U.; Uddin, Shahab; Jeremijenko, Andrew Martin; Nimir, Mai; Abu-Raddad, Laith J.; Abid, Fatma Ben; Zaqout, Ahmed; Alfheid, Sameer R.; Saqr, Hassan Mohamed Hassan; Omrani, Ali S.; Hssain, Ali Ait; Al Maslamani, Muna; Yassine, Hadi M.; Dermime, Said... more authors ... less authors ( Frontiers Media , 2023 , Article)Introduction: The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods: ... -
Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications
Al-Nesf, Maryam A. Y.; Abdesselem, Houari B.; Bensmail, Ilham; Ibrahim, Shahd; Saeed, Walaa A. H.; Mohammed, Sara S. I.; Razok, Almurtada; Alhussain, Hashim; Aly, Reham M. A.; Al Maslamani, Muna; Ouararhni, Khalid; Khatib, Mohamad Y.; Hssain, Ali Ait; Omrani, Ali S.; Al-Kaabi, Saad; Al Khal, Abdullatif; Al-Thani, Asmaa A.; Samsam, Waseem; Farooq, Abdulaziz; Al-Suwaidi, Jassim; Al-Maadheed, Mohammed; Al-Siddiqi, Heba H.; Butler, Alexandra E.; Decock, Julie V.; Mohamed-Ali, Vidya; Al-Ejeh, Fares... more authors ... less authors ( Nature Research , 2022 , Article)COVID-19 complications still present a huge burden on healthcare systems and warrant predictive risk models to triage patients and inform early intervention. Here, we profile 893 plasma proteins from 50 severe and 50 ... -
A Prospective Cohort Study (OUTSTRIP-COVID) on Functional and Spirometry Outcomes in COVID-19 ICU Survivors at 3 Months
Thomas, Merlin; Raza, Tasleem; Hameed, Mansoor; Sharma, Rohit; Rajagopal, Rajalekshmi Maheswari; Adab, Aisha Hussain O.Al; Ahmad, Mushtaq; George, Saibu; Hussein, Mousa; Akram, Jaweria; Ibrahim, Mohamed Izham Mohamed; Hssain, Ali Ait; Yousaf, Muhammad; Khatib, Mohamad Yahya... more authors ... less authors ( Taylor & Francis Group , 2023 , Article)Purpose: COVID-19 pandemic resulted in a significant number of critical care admissions secondary to severe pneumonia and acute respiratory distress syndrome. We evaluated the short-, medium-and long-term outcomes of lung ... -
Towards next generation cannulation simulators
Mahmoud, Abdulrahman; Khurshid, Uzair; Abducarim, Aiman; Mahmud, Sakib; Abdallah, Omrane; Mohamed, Elshaikh; Alsalemi, Abdullah; Bensaali, Faycal; Amira, Abbes; Hssain, Ali Ait; Alinier, Guillaume; Hassan, Ibrahim... more authors ... less authors ( Hamad bin Khalifa University Press (HBKU Press) , 2020 , Article)Background: Cannulation, in extracorporeal membrane oxygenation (ECMO), is the act of inserting a cannula through the body1. For femoral veins, femoral arteries, and the jugular vein, the cannula stops at the inferior vena ...