Browsing by Author "Al Moustafa, Ala-Eddin"
Now showing items 41-60 of 81
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Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing
Augustine, Robin; Hasan, Anwarul; Dalvi, Yogesh B.; Rehman, Syed Raza Ur; Varghese, Ruby; Unni, Raghunath Narayanan; Yalcin, Huseyin C.; Alfkey, Rashad; Thomas, Sabu; Al Moustafa, Ala Eddin... more authors ... less authors ( Elsevier , 2021 , Article)© 2020 The Authors Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and ... -
Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
Alateyah, Nouralhuda; Ahmad, Salma M. S.; Gupta, Ishita; Fouzat, Arij; Thaher, Mahmoud Ibrahim; Das, Probir; Al Moustafa, Ala-Eddin; Ouhtit, Allal... more authors ... less authors ( Frontiers Media S.A. , 2022 , Article)Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ... -
HER-2/Epstein-Barr virus crosstalk in human gastric carcinogenesis: A novel concept of oncogene/oncovirus interaction.
Cyprian, Farhan S; Al-Antary, Noor; Al Moustafa, Ala-Eddin ( Taylor & Francis , 2018 , Article)Gastric cancer is the fourth most common cancer and the second leading cause of cancer deaths worldwide. Additionally, it is well-known that metastatic cancer disease is a major cause of morbidity and mortality in cancer ... -
High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human Cervical Cancer: Recent Evidence and Future Directions
Allouch, Soumaya; Malki, Ahmed; Allouch, Asma; Gupta, Ishita; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( Frontiers Media , 2020 , Article)Cervical cancer is the fourth most common malignancy in women worldwide and a leading cause of cancer-related mortality in developing countries. Important etiological factors in this cancer are high-risk human papillomaviruses ... -
High-Risk Human Papillomaviruses (HPV) and Epstein - Barr virus (EBV) are Commonly Present in Rectal Cancer
Gupta, Ishita; Jabeen, Ayesha; Skenderi, Faruk; Malki, Mohammed; Al-Thawadi, Hamda; Al Moustafa, Ala‑Eddin; Vranic, Semir... more authors ... less authors ( Springer Nature , 2020 , Conference Paper)Background: Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) are well-established oncoviruses that can be co-present and cooperate in the initiation and/or progression of various human cancers. We recently reported ... -
High-risk human papillomaviruses and Epstein-Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study.
Nagi, Karim; Gupta, Ishita; Jurdi, Nawaf; Jabeen, Ayesha; Yasmeen, Amber; Batist, Gerald; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( BMC , 2021 , Article)High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein-Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as head and ... -
High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer and Their Association with Clinicopathological Status.
Gupta, Ishita; Al Farsi, Halema; Jabeen, Ayesha; Skenderi, Faruk; Al-Thawadi, Hamda; AlAhmad, Yaman M; Al Moustafa, Ala-Eddin; Vranic, Semir... more authors ... less authors ( MDPI , 2020 , Article)Colorectal cancer (CRC) is a common malignancy with a high mortality rate worldwide. It is a complex, multifactorial disease that is strongly impacted by both hereditary and environmental factors. The role of microbes ... -
High-risk human papillomaviruses and epstein-barr virus presence and crosstalk in human oral carcinogenesis
Al Moustafa, Ala Eddin; Cyprian, Farhan S.; Al-Antary, Noor; Yasmeen, Amber ( Springer International Publishing , 2017 , Book chapter)Oral cancer is the most frequent type of malignancy of the head and neck area worldwide. This cancer is a major cause of mortality in several parts of the world especially in certain Asian countries. In fact, the majority ... -
High-risk human papillomaviruses and Epstein–Barr virus in breast cancer in Lebanese women and their association with tumor grade: a molecular and tissue microarray study
Nagi, Karim; Gupta, Ishita; Jurdi, Nawaf; Jabeen, Ayesha; Yasmeen, Amber; Batist, Gerald; Vranic, Semir; Al-Moustafa, Ala Eddin... more authors ... less authors ( Springer Nature , 2021 , Article)Background: High-risk human papillomaviruses (HPVs) are present and can cooperate with Epstein–Barr virus (EBV) to initiate and/or enhance the progression of several types of human carcinomas including cervical as well as ... -
HPV and Recurrent Respiratory Papillomatosis: A Brief Review
Ouda, Amr Mohamed; Elsabagh, Ahmed Adel; Elmakaty, Ibrahim Mohamed; Gupta, Ishita; Vranic, Semir; Al-Thawadi, Hamda; Al Moustafa, Ala-Eddin... more authors ... less authors ( MDPI , 2021 , Article)Recurrent Respiratory Papillomatosis (RRP) is a rare but severe manifestation of human papillomavirus (HPV). As our knowledge about HPV infections has expanded, it has become possible to understand the course of RRP disease ... -
Human Papillomaviruses and Epstein-Barr Virus Interactions in Colorectal Cancer: A Brief Review.
Fernandes, Queenie; Gupta, Ishita; Vranic, Semir; Al Moustafa, Ala-Eddin ( MDPI , 2020 , Article)Human papillomaviruses (HPVs) and the Epstein-Barr virus (EBV) are the most common oncoviruses, contributing to approximately 10%-15% of all malignancies. Oncoproteins of high-risk HPVs (E5 and E6/E7), as well as EBV (LMP1, ... -
Human Papillomaviruses-Related Cancers: An Update on the Presence and Prevention Strategies in the Middle East and North African Regions.
Fernandes, Queenie; Allouch, Soumaya; Gupta, Ishita; Elmakaty, Ibrahim; Elzawawi, Khaled E; Amarah, Ahmed; Al-Thawadi, Hamda; Al-Farsi, Halema; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( MDPI , 2022 , Article Review)The human papillomavirus (HPV) is a non-enveloped double-stranded DNA virus capable of infecting skin and mucosa epithelial cells. Commonly, HPV infection is associated with sexually transmitted diseases and is considered ... -
The Impact of Pamam Dendrimers on Her2-Positive Breast Cancer and the Early Stages of Embryogenesis
Kheraldine, Hadeel (2020 , Master Thesis)Poly (amidoamine) (PAMAM) dendrimers are widely used in drug delivery systems and gene transfection as drug carriers. They also exert several biological effects including modulating gene expression and interfering with ... -
Impact of single-walled carbon nanotubes on the embryo: a brief review
Al Moustafa, Ala-Eddin; Mfoumou, Etienne; Roman, Dacian E.; Nerguizian, Vahe; Alazzam, Anas; Stiharu, Ion; Yasmeen, Amber... more authors ... less authors ( Dove Press , 2016 , Article)Carbon nanotubes (CNTs) are considered one of the most interesting materials in the 21st century due to their unique physiochemical characteristics and applicability to various industrial products and medical applications. ... -
Implications of Gut Microbiota in Epithelial–Mesenchymal Transition and Cancer Progression: A Concise Review
Gupta, Ishita; Pedersen, Shona; Vranic, Semir; Al Moustafa, Ala Eddin ( MDPI , 2022 , Article Review)Advancement in the development of molecular sequencing platforms has identified infectious bacteria or viruses that trigger the dysregulation of a set of genes inducing the epithelial– mesenchymal transition (EMT) event. ... -
Incidence of HPVs, EBV and MMTV-like Virus in Breast Cancer in Qatar.
Gupta, Ishita; Al-Sarraf, Reem; Farghaly, Hanan; Vranic, Semir; Sultan, Ali A; Al-Thawadi, Hamda; Al Moustafa, Ala-Eddin; Al-Farsi, Halema F... more authors ... less authors ( Karger Publishers , 2022 , Article)Human papillomaviruses (HPVs), Epstein-Barr virus (EBV), and mouse mammary tumor virus-like virus (MMTV-like virus) can be present and contribute to breast cancer development and progression. However, the role of these ... -
Mesoporous silica coated carbon nanofibers reduce embryotoxicity via ERK and JNK pathways
Abdo, Ghada G.; Gupta, Ishita; Kheraldine, Hadeel; Rizeq, Balsam; Zagho, Moustafa M.; Khalil, Ashraf; Elzatahry, Ahmed; Al Moustafa, Ala-Eddin... more authors ... less authors ( Elsevier Ltd , 2021 , Article)Carbon nanofibers (CNFs) have been implicated in biomedical applications, yet, they are still considered as a potential hazard. Conversely, mesoporous silica is a biocompatible compound that has been used in various ... -
MXene Nanosheets May Induce Toxic Effect on the Early Stage of Embryogenesis.
Alhussain, Hashim; Augustine, Robin; Hussein, Essraa A; Gupta, Ishita; Hasan, Anwarul; Al Moustafa, Ala-Eddin; Elzatahry, Ahmed... more authors ... less authors ( American Scientific Publishers , 2020 , Article)MXene (Ti₃C₂T), as a novel 2D material, has produced a great interest due to its promising properties in biomedical applications, nevertheless, there is a lack of studies dedicated to investigate the possible toxic effect ... -
Naked Poly(amidoamine) Dendrimer Nanoparticles Exhibit Intrinsic Embryotoxicity During the Early Stages of Normal Development.
Kheraldine, Hadeel; Gupta, Ishita; Alhussain, Hashim; Jabeen, Ayesha; Akhtar, Saghir; Al Moustafa, Ala-Eddin; Rachid, Ousama... more authors ... less authors ( American Science Publishers ASP , 2020 , Article)To investigate the impact of poly(amidoamine) dendrimers (PAMAMs) in the embryo, we explored the outcome of different generations (G₄ and G) on the early stages of embryogenesis using the chicken embryo as a model. We also ... -
A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells.
Augustine, Robin; Alhussain, Hashim; Hasan, Anwarul; Badie Ahmed, Mohamed; C Yalcin, Huseyin; Al Moustafa, Ala-Eddin... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2019 , Article)Cancer metastasis is the leading cause of cancer-related mortality worldwide. To date, several in vitro methodologies have been developed to understand the mechanisms of cancer metastasis and to screen various therapeutic ...