Browsing by Author "Morsi, Hisham"
Now showing items 1-2 of 2
-
Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar
Ismail, Mohamed A; Samara, Muthanna; Al Sayab, Ali; Alsharshani, Mohamed; Yassin, Mohamed A; Varadharaj, Govindarajulu; Vezzalini, Marzia; Tomasello, Luisa; Monne, Maria; Morsi, Hisham; Qoronfleh, M Walid; Zayed, Hatem; Cook, Richard; Sorio, Claudio; Modjtahedi, Helmout; Al-Dewik, Nader I... more authors ... less authors ( Wiley Open Access , 2020 , Article)Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ... -
Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies.
Younes, Salma; Ismail, Mohamed A; Al-Jurf, Rana; Ziyada, Ayah; Nasrallah, Gheyath K; Abdulrouf, Palli Valapila; Nagy, Mohamed; Zayed, Hatem; Farrell, Thomas; Sorio, Claudio; Morsi, Hisham; Qoronfleh, M Walid; Al-Dewik, Nader I... more authors ... less authors ( taylor and francis online , 2023 , Article)Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ...