• Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions [version 1; referees: 2 approved] 

      BangaBangash M.A.; Alles, Sascha R. A.; Santana-Varela, Sonia; Millet, Queensta; Sikandar, Shafaq; ... more authors ( F1000 Research Ltd , 2018 , Article)
      Background: Sensory neurons play an essential role in almost all pain conditions, and have recently been classified into distinct subsets on the basis of their transcriptomes. Here we have analysed alterations in dorsal ...
    • A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids 

      Ramdas, Shweta; Judd, Jonathan; Graham, Sarah E.; Kanoni, Stavroula; Wang, Yuxuan; ... more authors ( Elsevier , 2022 , Article)
      A major challenge of genome-wide association studies (GWASs) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ...
    • Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function 

      Jami, Sina; Deuis, Jennifer R.; Klasfauseweh, Tabea; Cheng, Xiaoyang; Kurdyukov, Sergey; ... more authors ( Nature Research , 2023 , Article)
      Voltage-gated sodium (NaV) channels are critical regulators of neuronal excitability and are targeted by many toxins that directly interact with the pore-forming α subunit, typically via extracellular loops of the ...