Browsing by Subject "Article"
Now showing items 41-60 of 76
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Investigating clinicians' determinants of antimicrobial prescribing behaviour using the Theoretical Domains Framework
( W.B. Saunders Ltd , 2022 , Article)Aim: To identify and quantify potential determinants of antimicrobial prescribing behaviour, using the Theoretical Domains Framework (TDF). Methods: A cross-sectional survey involving doctors (?4000) and pharmacists (?400) ... -
Is there truly an increase in risk of cardiovascular and hematological adverse events with vascular endothelial growth factor receptor tyrosine kinase inhibitors?
( Taylor and Francis Ltd , 2020 , Article)Objectives: Recent studies have shown an increase risk of cardiovascular and hematological adverse events associated with vascular endothelial growth factor tyrosine kinase inhibitors (VEGF-TKIs). The authors hypothesize ... -
Isolation and Physicochemical Characterization of Laccase from Ganoderma lucidum-CDBT1 Isolated from Its Native Habitat in Nepal
( Hindawi Limited , 2016 , Article)At present, few organisms are known to and capable of naturally producing laccases and white rot fungi are one such group. In the present study, three fungal species, namely, Ganoderma lucidum-CDBT1, Ganoderma japonicum, ... -
Locality Sensitive Deep Learning for Detection and Classification of Nuclei in Routine Colon Cancer Histology Images
( Institute of Electrical and Electronics Engineers Inc. , 2016 , Article)Detection and classification of cell nuclei in histopathology images of cancerous tissue stained with the standard hematoxylin and eosin stain is a challenging task due to cellular heterogeneity. Deep learning approaches ... -
Magnetic mesoporous nanospheres anchored with LyP-1 as an efficient pancreatic cancer probe
( Elsevier Ltd , 2017 , Article)Immobilization of a ligand that selectively interacts with cancer cells to nanomaterials can enhance their diagnostic and therapeutic efficiency. In this study, we firstly demonstrate the high expression of receptor for ... -
Metronidazole in conjunction with penicillin neither prevents recurrence nor enhances recovery from peritonsillar abscess when compared with penicillin alone: A prospective, double-blind, randomized, placebo-controlled trial
( Oxford University Press , 2016 , Article)Objectives The objectives of this study were to evaluate the efficacy of metronidazole in conjunction with penicillin in preventing the recurrence of peritonsillar abscess (PTA) and to learn whether metronidazole enhances ... -
Mortality prediction utilizing blood biomarkers to predict the severity of COVID-19 using machine learning technique
( MDPI , 2021 , Article)Healthcare researchers have been working on mortality prediction for COVID-19 patients with differing levels of severity. A rapid and reliable clinical evaluation of disease intensity will assist in the allocation and ... -
Multiscale structural evolution of citrate-triggered intrafibrillar and interfibrillar mineralization in dense collagen gels
( Academic Press Inc. , 2020 , Article)The mineralized extracellular matrix of bone is an organic?inorganic nanocomposite consisting primarily of carbonated hydroxyapatite, fibrous type I collagen, noncollagenous proteins, proteoglycans, and diverse biomolecules ... -
Nanotoxicology of dendrimers in the mammalian heart: Ex vivo and in vivo administration of g6 pamam nanoparticles impairs recovery of cardiac function following ischemia-reperfusion injury
( Dove Medical Press Ltd. , 2020 , Article)Aim: The effects of polyamidoamine (PAMAM) dendrimers on the mammalian heart are not completely understood. In this study, we have investigated the effects of a sixth-generation cationic dendrimer (G6 PAMAM) on cardiac ... -
Needle-free Mental Incisive Nerve Block: In vitro, Cadaveric, and Pilot Clinical Studies
( Elsevier B.V. , 2021 , Article)The present study aimed to optimize Needle-Free Liquid Jet Injection (NFLJI) for Mental Incisive Nerve Blocks (MINB) and evaluate its clinical safety and feasibility. A MINB protocol was developed and optimized by series ... -
NiFe2O4/poly(ethylene glycol)/lipid-polymer hybrid nanoparticles for anti-cancer drug delivery
( Royal Society of Chemistry , 2020 , Article)The present study reports the fabrication of hybrid nanoparticles consisting of nickel ferrite (NFO) for anti cancer drug delivery. The hybrid system was formulated from poly(vinyl alcohol)/stearic acid with PEG containing ... -
Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
( Taylor and Francis Ltd , 2016 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
Novel methodology for facile fabrication of nanofiltration membranes based on nucleophilic nature of polydopamine
( Elsevier B.V. , 2016 , Article)Novel methodology for facilely fabricating nanofiltration (NF) composite membrane has been successfully developed by employing nucleophilic nature of polydopamine (PDA) chemistry. The self-polymerized PDA coating over ... -
Open-label study of absorption and clearance of 1% voriconazole eye drops
( American Society for Microbiology , 2016 , Article)Twenty participants undergoing elective cataract surgery received 1% voriconazole eye drops (1 drop per eye) either 20, 40, 60, or 80 min before surgery. Median voriconazole concentrations of 1.9 to 3.2 mg/liter in aqueous ... -
Optical absorption enhancement in polymer BHJ thin film using Ag nanostructures: A simulation study
( Bentham Science Publishers , 2020 , Article)Background: The photo-absorption and light trapping through the different layers of the organic solar cell structures are a growing concern now-a-days as it affects dramatically the overall efficiency of the cells. In fact, ... -
Osseointegration Pharmacology: A Systematic Mapping Using Artificial Intelligence
( Acta Materialia Inc , 2021 , Article)Clinical performance of osseointegrated implants could be compromised by the medications taken by patients. The effect of a specific medication on osseointegration can be easily investigated using traditional systematic ... -
Ovarian torsion: A retrospective case series at a tertiary care center emergency department
( Public Library of Science , 2024 , Article)Ovarian torsion (OT) is a gynecological emergency that can have diverse clinical presentations makings its diagnosis especially challenging. Few studies exist in the literature describing the clinical presentation as well ... -
Patient-Specific Seizure Detection Using Nonlinear Dynamics and Nullclines
( Institute of Electrical and Electronics Engineers Inc. , 2020 , Article)Nonlinear dynamics has recently been extensively used to study epilepsy due to the complex nature of the neuronal systems. This study presents a novel method that characterizes the dynamic behavior of pediatric seizure ... -
Postoperative administration of the acetylcholinesterase inhibitor, donepezil, interferes with bone healing and implant osseointegration in a rat model
( MDPI AG , 2020 , Article)Donepezil is an acetylcholinesterase inhibitor commonly used to treat mild to moderate Alzheimer?s disease. Its use has been associated with increased bone mass in humans and animals. However, the effect of postoperative ... -
Preliminary design of an actuated imaging probe for generation of additional visual cues in a robotic surgery
( Springer New York LLC , 2016 , Article)Background The aim of this study was to enhance the visual feedback of surgeons, during robotic surgeries, by designing and developing an actuated 2D imaging probe, which is used in conjunction with the traditional ...