Browsing by Author "Yalcin, Huseyin C"
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Editorial: Emerging mechanisms in cardiovascular disease
Yalcin, Huseyin C.; Caiazzo, Elisabetta; Ialenti, Armando; Eid, Ali H. ( Frontiers Media , 2023 , Other)Editorial on the Research Topic Emerging mechanisms in cardiovascular disease The leading cause of worldwide mortality is cardiovascular disease (CVD) (Aboukhater et al., 2023). Despite many significant advances in the ... -
Effect of cell-phone radiofrequency on angiogenesis and cell invasion in human head and neck cancer cells.
Alahmad, Yaman M; Aljaber, Mohammed; Saleh, Alaaeldin I; Yalcin, Huseyin C; Aboulkassim, Tahar; Yasmeen, Amber; Batist, Gerald; Moustafa, Ala-Eddin Al... more authors ... less authors ( Wiley , 2018 , Article)Today, the cell phone is the most widespread technology globally. However, the outcome of cell-phone radiofrequency on head and neck cancer progression has not yet been explored. The chorioallantoic membrane (CAM) and human ... -
Effect of flow-induced shear stress in nanomaterial uptake by cells: Focus on targeted anti-cancer therapy
Shurbaji, Samar; Anlar, Gulsen G.; Hussein, Essraa A.; Elzatahry, Ahmed; Yalcin, Huseyin C. ( MDPI , 2020 , Article)© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Recently, nanomedicines have gained a great deal of attention in diverse biomedical applications, including anti-cancer therapy. Being different from normal tissue, ... -
Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome.
Salman, Huseyin Enes; Alser, Maha; Shekhar, Akshay; Gould, Russell A; Benslimane, Fatiha M; Butcher, Jonathan T; Yalcin, Huseyin C... more authors ... less authors ( Springer , 2021 , Article)Congenital heart defects (CHDs) are abnormalities in the heart structure present at birth. One important condition is hypoplastic left heart syndrome (HLHS) where severely underdeveloped left ventricle (LV) cannot support ... -
Effect of Water-Pipe Smoking on the Normal Development of Zebrafish
Zakaria, Zain Zaki; Aladwi, Shaima Ahmad; Benslimane, Fatiha; Al-Absi, Enas S.; Al-Shafai, Mashael; Yalcin, Huseyin C.; Khalil, Ashraf; Al Moustafa, Ala-Eddin; Al-Asmakh, Maha... more authors ... less authors ( MDPI , 2021 , Article)Background: Among all types of tobacco consumption,Water-Pipe Smoking (WPS) is the most widely used in the Middle East and second-most in several other countries. The effect of WPS on normal development is not yet fully ... -
Elaeagnus angustifolia Plant Extract Inhibits Angiogenesis and Downgrades Cell Invasion of Human Oral Cancer Cells via Erk1/Erk2 Inactivation.
Saleh, Alaaeldin I; Mohamed, Islam; Mohamed, Ahmed A.; Abdelkader, Mennatallah; Yalcin, Huseyin C.; Aboulkassim, Tahar; Batist, Gerald; Yasmeen, Amber; Al Moustafaa, Ala-Eddin... more authors ... less authors ( Taylor & Francis (Routledge) , 2018 , Article)Oral cancer is a common malignancy in both men and women worldwide; this cancer is characterized by a marked propensity for invasion and spreading to local lymph nodes. On the other hand, Elaeagnus angustifolia (EA) is a ... -
Electrospun polylactic acid/date palm polyphenol extract nanofibres for tissue engineering applications
Khadija M., Zadeh; Luyt, Adriaan S.; Zarif, Lubna; Augustine, Robin; Hasan, Anwarul; Messori, Massimo; Hassan, Mohammad K.; Yalcin, Huseyin C.... more authors ... less authors ( Springer , 2019 , Article)In this study, a set of polylactic acid (PLA)/polyphenol extracted from date palm fruit (DP) blends were prepared by electrospinning process to be used as cell culture scaffolds for tissue engineering applications. For ... -
Evaluation of Metal-Organic Framework MIL-89 Nanoparticles Toxicity on Embryonic Zebrafish Development
Dana E., Al-Ansari; Al-Badr, Mashael; Zakaria, Zain Z.; Mohamed, Nura Adam; Nasrallah, Gheyath K.; Yalcin, Huseyin C.; Abou-Saleh, Haissam... more authors ... less authors ( Elsevier , 2022 , Article)Metal-Organic Framework MIL-89 nanoparticles garnered remarkable attention for their widespread use in technological applications. However, the impact of these nanomaterials on human and environmental health is still ... -
Experimental Assessment of Cardiovascular Physiology in the Chick Embryo.
Sukumaran, Vijayakumar; Mutlu, Onur; Murtaza, Mohammad; Alhalbouni, Rawia; Dubansky, Benjamin; Yalcin, Huseyin C... more authors ... less authors ( American Association for Anatomy Journals , 2023 , Article Review)High resolution assessment of cardiac functional parameters is crucial in translational animal research. The chick embryo is a historically well-used in vivo model for cardiovascular research due to its many practical ... -
Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model
Kuttikrishnan, Shilpa; Hasan, Maram; Prabhu, Kirti S.; El-Elimat, Tamam; Oberlies, Nicholas H.; Pearce, Cedric J.; Alali, Feras Q.; Ahmad, Aamir; Pourkarimi, Ehsan; Bhat, Ajaz A.; Yalcin, Huseyin C.; Uddin, Shahab... more authors ... less authors ( Elsevier Inc. , 2024 , Article)Neosetophomone B (NSP–B) is a unique meroterpenoid fungal secondary metabolite that has previously demonstrated promising anti-cancer properties against various cancer cell lines in vitro. However, its in vivo anti-cancer ... -
Fabrication and In Vitro Characterization of a Tissue Engineered PCL-PLLA Heart Valve.
Hasan, Anwarul; Soliman, Sherif; El Hajj, Fatima; Tseng, Yuan-Tsan; Yalcin, Huseyin C; Marei, Hany Elsayed... more authors ... less authors ( Nature Publishing Group , 2018 , Article)Heart valve diseases are among the leading causes of cardiac failure around the globe. Nearly 90,000 heart valve replacements occur in the USA annually. Currently, available options for heart valve replacement include ... -
The First International Zebrafish Conference/Workshop in Qatar.
Yalcin, Huseyin C; Benslimane, Fatiha M; Kawakami, Koichi ( Mary Ann Liebert , 2019 , Article)A zebrafish conference/workshop was held in Qatar between April 13 and 17, 2019. The aim of the event was to promote zebrafish research in Qatar and in Middle East/Asia by bringing together local zebrafish researchers with ... -
From Acellular Matrices to Smart Polymers: Degradable Scaffolds that are Transforming the Shape of Urethral Tissue Engineering.
Abbas, Tariq O; Yalcin, Huseyin C; Pennisi, Cristian P ( MDPI , 2019 , Article)Several congenital and acquired conditions may result in severe narrowing of the urethra in men, which represent an ongoing surgical challenge and a significant burden on both health and quality of life. In the field of ... -
Functional characterization of human myosin-binding protein C3 variants associated with hypertrophic cardiomyopathy reveals exon-specific cardiac phenotypes in zebrafish model
Da'as, Sahar I.; Yalcin, Huseyin C.; Nasrallah, Gheyath K.; Mohamed, Iman A.; Nomikos, Michail; Yacoub, Magdi H.; Fakhro, Khalid A.... more authors ... less authors ( Wiley , 2020 , Article)© 2020 Wiley Periodicals, Inc. Myosin-binding protein C 3 (MYBPC3) variants are the most common cause of hypertrophic cardiomyopathy (HCM). HCM is a complex cardiac disorder due to its significant genetic and clinical ... -
Generating an imagingbased approach for enhanced structural and functional analysis of zebrafish cardiovascular systems
yalcin, huseyin c; Abuhabib, UmmaySalma; Kitaz, Naila; Mohamed, Ala; Zakaria, Zain ( HBKU Press , 2018 , Conference Proceedings)Cardiovascular diseases (CVDs) have latterly become one of the leading cause of death and impairment worldwide. According to the World Health Organization (WHO), data estimation in 2008 were about 17.3, 7.3 and 6.2 million ... -
Growth factor loaded in situ photocrosslinkable poly(3-hydroxybutyrate-co-3-hydroxyvalerate)/gelatin methacryloyl hybrid patch for diabetic wound healing
Augustine, Robin; Hasan, Anwarul; Dalvi, Yogesh B.; Rehman, Syed Raza Ur; Varghese, Ruby; Unni, Raghunath Narayanan; Yalcin, Huseyin C.; Alfkey, Rashad; Thomas, Sabu; Al Moustafa, Ala Eddin... more authors ... less authors ( Elsevier , 2021 , Article)© 2020 The Authors Management of chronic diabetic ulcers remains as a major challenge in healthcare which requires extensive multidisciplinary approaches to ensure wound protection, management of excess wound exudates and ... -
Heart function and hemodynamic analysis for zebrafish embryos
Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( John Wiley and Sons Inc. , 2017 , Article Review)The Zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
Heart Function and Hemodynamics Analysis for Zebrafish Embryos
Yalcin, Huseyin C.; Amindari, Armin; Butcher, Jonathan T.; Althani, Asma; Yacoub, Magdi ( Wiley , 2017 , Article)The zebrafish has emerged to become a powerful vertebrate animal model for cardiovascular research in recent years. Its advantages include easy genetic manipulation, transparency, small size, low cost, and the ability to ... -
Hemodynamic Studies for Analyzing the Teratogenic Effects of Drugs in the Zebrafish Embryo.
yalcin, huseyin c ( Humana Press , 2018 , Book chapter)Investigations of teratogenic effects of drugs generally involve testing the drug on animals and zebrafish embryo is a commonly used animal model for that purpose. In these studies, cardiovascular function of the animals ... -
In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
Maram, Hasan; Zedan, Hadeel T.; Al-Fakhroo, Dana; Elsayed Ibrahim, Hend; Abiib, Sumaya Ibrahim; El-Sherbiny, Ibrahim M.; Yalcin, Huseyin C.... more authors ... less authors ( Elsevier , 2024 , Article)Heart failure (HF) is a multifactorial, heterogeneous systemic disease that is considered one of the leading causes of death and morbidity worldwide. It is well-known that endothelial dysfunction (ED) plays an important ...