Browsing by Author "Abou-Saleh, Haissam"
Now showing items 21-26 of 26
-
Nox2 activity is required in obesity-mediated alteration of bone remodeling
Rahman, Md Mizanur; El Jamali, Amina; Halade, Ganesh V.; Ouhtit, Allal; Abou-Saleh, Haissam; Pintus, Gianfranco... more authors ... less authors ( Hindawi Limited , 2018 , Article)Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ... -
Protective Effect of Cyclically Pressurized Solid⁻Liquid Extraction Polyphenols from Grape Pomace on Oxidative Endothelial Cell Death.
Posadino, Anna Maria; Biosa, Grazia; Zayed, Hatem; Abou-Saleh, Haissam; Cossu, Annalisa; Nasrallah, Gheyath K; Giordo, Roberta; Pagnozzi, Daniela; Porcu, Maria Cristina; Pretti, Luca; Pintus, Gianfranco... more authors ... less authors ( MDPI , 2018 , Article)The aim of this work is the evaluation of a green extraction technology to exploit winery waste byproducts. Specifically, a solid⁻liquid extraction technology (Naviglio Extractor) was used to obtain polyphenolic antioxidants ... -
Recent Developments in Nanomaterials-Based Drug Delivery and Upgrading Treatment of Cardiovascular Diseases
Mohamed, Nura A.; Marei, Isra; Crovella, Sergio; Abou-Saleh, Haissam ( MDPI , 2022 , Article)Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. However, despite the recent developments in the management of CVDs, the early and long outcomes vary considerably in patients, ... -
Studies on metal–organic framework (MOF) nanomedicine preparations of sildenafil for the future treatment of pulmonary arterial hypertension
Mohamed, Nura A.; Abou-Saleh, Haissam; Kameno, Yu; Marei, Isra; de Nucci, Gilberto; Ahmetaj-Shala, Blerina; Shala, Fisnik; Kirkby, Nicholas S.; Jennings, Lewis; Al-Ansari, Dana E.; Davies, Robert P.; Lickiss, Paul D.; Mitchell, Jane A.... more authors ... less authors ( nature , 2021 , Article)Pulmonary arterial hypertension (PAH) is an incurable disease, although symptoms are treated with a range of dilator drugs. Despite their clinical benefits, these drugs are limited by systemic side-effects. It is, therefore, ... -
Think like a Virus: Toward Improving Nanovaccine Development against SARS-CoV-2
Mohamed, Nura A.; Abou-Saleh, Haissam; Mohamed, Hana A.; Al-Ghouti, Mohammad A.; Crovella, Sergio; Zupin, Luisa... more authors ... less authors ( MDPI , 2022 , Article Review)There is no doubt that infectious diseases present global impact on the economy, society, health, mental state, and even political aspects, causing a long-lasting dent, and the situation will surely worsen if and when the ... -
Validation of a Novel Fluorescent Lateral Flow Assay for Rapid Qualitative and Quantitative Assessment of Total Anti-SARS-CoV-2 S-RBD Binding Antibody Units (BAU) from Plasma or Fingerstick Whole-Blood of COVID-19 Vaccinees
Younes, Nadin; Al-Sadeq, Duaa W.; Shurrab, Farah M.; Zedan, Hadeel T.; Abou-Saleh, Haissam; Abo-Halawa, Bushra Y.; AlHamaydeh, Fatima M.; Elsharafi, Amira E.; Daas, Hanin I.; Thomas, Swapna; Aboalmaaly, Sahar; Al Farsi, Afra; Al-Buainain, Reeham; Ataelmannan, Samar; Paul, Jiji; Al Saadi, Amana Salih; Yassine, Hadi M.; Majdalawieh, Amin F.; Ismail, Ahmed; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2022 , Article)Background: Limited commercial LFA assays are available to provide a reliable quantitative measurement of the total binding antibody units (BAU/mL) against the receptor-binding domain of the SARS-CoV-2 spike protein (S-RBD). ...