Browsing by Author "Yassine, Hadi M."
Now showing items 21-40 of 168
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Characterizing the effective reproduction number during the COVID-19 pandemic: Insights from Qatar’s experience
Bsat, Raghid; Chemaitelly, Hiam; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; Al Kanaani, Zaina; Al Kuwari, Einas; Butt, Adeel A; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Nasrallah, Gheyath K; Benslimane, Fatiha M; Al Khatib, Hebah A; Yassine, Hadi M; Al Kuwari, Mohamed G; Al Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al Kha, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J; Ayoub, Houssein H... more authors ... less authors ( International Society of Global Health , 2022 , Article)Background: The effective reproduction number, Rt, is a tool to track and understand epidemic dynamics. This investigation of Rt estimations was conducted to guide the national COVID-19 response in Qatar, from the onset ... -
Clinical manifestations associated with acute viral gastroenteritis pathogens among pediatric patients in Qatar.
Abdel-Rahman, Manar E; Mathew, Shilu; Al Thani, Asmaa A; Ansari, Khalid Al; Yassine, Hadi M ( Wiley , 2021 , Article)Acute gastroenteritis (AGE) remains a significant cause of diarrhea that affects children worldwide. It is usually caused by viral agents, including rotavirus (RV), norovirus (NoV), adenovirus (AdV), astrovirus (AstV), and ... -
Comparative analysis of within-host diversity among vaccinated COVID-19 patients infected with different SARS-CoV-2 variants
Hebah A., Al-Khatib; Smatti, Maria K.; Ali, Fatma H.; Zedan, Hadeel T.; Thomas, Swapna; Ahmed, Muna N.; El-kahlout, Reham A.; Al Bader, Mashael A.; Elgakhlab, Dina; Coyle, Peter V.; Abu-Raddad, Laith J.; Al Thani, Asma A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a rapidly evolving RNA virus that mutates within hosts and exists as viral quasispecies. Here, we evaluated the within-host diversity among vaccinated and ... -
Comparison of antibody immune responses between BNT162b2 and mRNA-1273 SARS-CoV-2 vaccines in naïve and previously infected individuals.
Al-Sadeq, Duaa W; Shurrab, Farah M; Ismail, Ahmed; Amanullah, Fathima Humaira; Thomas, Swapna; Aldewik, Nader; Yassine, Hadi M; Abdul Rahim, Hanan F; Abu-Raddad, Laith; Nasrallah, Gheyath K... more authors ... less authors ( Oxford University Press , 2021 , Article)Two mRNA vaccines, Pfizer-BNT162b2 and Moderna-mRNA-1273, obtained the Emergency Use Listing by WHO for preventing COVID-19. However, little is known about the difference in antibody responses induced by these two mRNA ... -
Computational screening of known broad-spectrum antiviral small organic molecules for potential influenza HA stem inhibitors.
Mathew, Shilu; Al Thani, Asmaa A; Yassine, Hadi M ( Public Library of Science , 2018 , Article)With the emergence of new influenza virus strains that are resistant to current inhibitors such as oseltamivir (anti-neuraminidase (NA)) and amantadine (anti-M2 proton channel), influenza A viruses continue to be a serious ... -
Coronavirus Disease 2019 Disease Severity in Children Infected With the Omicron Variant
Butt, A.A.; Butt, Adeel A.; Dargham, Soha R.; Loka, Srusvin; Shaik, Riyazuddin M.; Chemaitelly, Hiam; Tang, Patrick; Hasan, Mohammad R.; Coyle, Peter V.; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Kaleeckal, Anvar H.; Latif, Ali Nizar; Zaqout, Ahmed; Almaslamani, Muna A.; Al Khal, Abdullatif; Bertollini, Roberto; Abou-Samra, Abdul Badi; Abu-Raddad, Laith J.... more authors ... less authors ( NLM (Medline) , 2022 , Article)SHORT SUMMARY: Severe acute respiratory syndrome coronavirus 2 infection from the Omicron variant in children/adolescents is less severe than infection from the Delta variant. Those 6 to <18 years also have less severe ... -
COVID-19 Disease Severity in Persons Infected with Omicron BA.1 and BA.2 Sublineages and Association with Vaccination Status
Butt, Adeel A.; Dargham, Soha R.; Coyle, Peter; Yassine, Hadi M.; Al-Khal, Abdullatif; Abou-Samra, Abdul Badi; Abu-Raddad, Laith J.... more authors ... less authors ( American Medical Association , 2022 , Other)[No abstract available] -
Covid-19 Vaccine Protection among Children and Adolescents in Qatar.
Chemaitelly, Hiam; AlMukdad, Sawsan; Ayoub, Houssein H; Altarawneh, Heba N; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H; Latif, Ali N; Shaik, Riyazuddin M; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed G; Al-Romaihi, Hamad E; Butt, Adeel A; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses. We assessed the real-world ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
Al Mana, Hassan; Yassine, Hadi M.; Youne, Nadin N.; Al-Mohannadi, Anjud; Al-Sadeq, Duaa W.; Alhababi, Dalal; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ... -
Demographic and Clinical Characteristics of Early Travel-Associated COVID-19 Cases
Marei, Reham M.; Emara, Mohamed M.; Elsaied, Omar M.; Nasrallah, Gheyath K.; Chivese, Tawanda; Al-Romaihi, Hamad E.; Althani, Mohamed H.; Al Thani, Asmaa A.; Farag, Elmoubasher A.; Yassine, Hadi M.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Marei, Emara, Elsaied, Nasrallah, Chivese, Al-Romaihi, Althani, Al Thani, Farag and Yassine. Background: SARS-CoV-2 continues to claim hundreds of thousands of people's lives. It mostly affects the elderly ... -
Demographics and Epidemiology of Hepatitis B in the State of Qatar: A Five-Year Surveillance-Based Incidence Study
Al Romaihi, Hamad E.; Ganesan, Nandakumar; Farag, Elmoubasher A.; Smatti, Maria K.; Nasrallah, Gheyath K.; Himatt, Sayed M.; Derbala, Moutaz F.; Alshamali, Maha; Mahadoon, Lylu K.; Khogali, Hayat S.; Sallam, Mohamed; Al Thani, Asmaa A.; Al Thani, Mohammed; Al Kaabi, Saad; Yassine, Hadi M.... more authors ... less authors ( MDPI , 2019 , Article)Background: Expatriates represent >80% of Qatar’s population, mostly arriving from countries in Africa and Asia that are endemic with many diseases. This increases the risk for introducing new pathogens into the country ... -
Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages.
Corbett, Kizzmekia S; Moin, Syed M; Yassine, Hadi M; Cagigi, Alberto; Kanekiyo, Masaru; Boyoglu-Barnum, Seyhan; Myers, Sky I; Tsybovsky, Yaroslav; Wheatley, Adam K; Schramm, Chaim A; Gillespie, Rebecca A; Shi, Wei; Wang, Lingshu; Zhang, Yi; Andrews, Sarah F; Joyce, M Gordon; Crank, Michelle C; Douek, Daniel C; McDermott, Adrian B; Mascola, John R; Graham, Barney S; Boyington, Jeffrey C... more authors ... less authors ( American Society for Microbiology , 2019 , Article)Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by current vaccines. ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
Nasarallah, Gheyath K.; Fakhroo, Aisha D.; Khan, Taushif; Cyprian, Farhan S.; Al Ali, Fatima; Ata, Manar M.A.; Taleb, Sara; Zedan, Hadeel T.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Hssain, Ali A.; Eid, Ali H.; Abu-Raddad, Laith J.; Al-Khal, Abdullatif; Al Thani, Asmaa A.; Marr, Nico; Yassine, Hadi M.... more authors ... less authors ( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; Dargham, Soha R.; Al-Dewik, Nader; Qotba, Hamda; Syed, Mohamed; Alnuaimi, Ahmed; Yassine, Hadi M.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2020 , Article)Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ... -
Distinct antibody repertoires against endemic human coronaviruses in children and adults.
Khan, Taushif; Rahman, Mahbuba; Al Ali, Fatima; Huang, Susie Sy; Ata, Manar; Zhang, Qian; Bastard, Paul; Liu, Zhiyong; Jouanguy, Emmanuelle; Beziat, Vivien; Cobat, Aurélie; Nasrallah, Gheyath K; Yassine, Hadi M; Smatti, Maria K; Saeed, Amira; Vandernoot, Isabelle; Goffard, Jean-Christophe; Smits, Guillaume; Migeotte, Isabelle; Haerynck, Filomeen; Meyts, Isabelle; Abel, Laurent; Casanova, Jean-Laurent; Hasan, Mohammad R; Marr, Nico... more authors ... less authors ( American Society for Clinical Investigation , 2021 , Article)Four endemic human coronaviruses (HCoVs) are commonly associated with acute respiratory infection in humans. B cell responses to these "common cold" viruses remain incompletely understood. Here we report a comprehensive ... -
Diversity of bacterial pathogens and their antimicrobial resistance profile among commensal rodents in Qatar
Islam, M.M.; Islam, Md Mazharul; Farag, Elmoubashar; Hassan, Mohammad Mahmudul; Enan, Khalid A.; Mohammad Sabeel, K. V.; Alhaddad, Maryam Mohammed; Smatti, Maria K.; Al-Marri, Abdulla Mohammad; Al-Zeyara, Abdul Azia; Al-Romaihi, Hamad; Yassine, Hadi M.; Sultan, Ali A.; Bansal, Devendra; Mkhize-Kwitshana, Zilungile... more authors ... less authors ( Springer Science and Business Media B.V. , 2022 , Article)Rodents are sources of many zoonotic pathogens that are of public health concern. This study investigated bacterial pathogens and assessed their antimicrobial resistance (AMR) patterns in commensal rodents in Qatar. A total ... -
Duration of immune protection of SARS-CoV-2 natural infection against reinfection.
Chemaitelly, Hiam; Nagelkerke, Nico; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Oxford University Press , 2022 , Article)The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect ... -
Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2022 , Article)SARS-CoV-2 Omicron BA.1 and BA.2 subvariants are genetically divergent. We conducted a matched, test-negative, case-control study to estimate duration of protection of the second and third/booster doses of mRNA COVID-19 ... -
Effect of mRNA Vaccine Boosters against SARS-CoV-2 Omicron Infection in Qatar.
Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Tang, Patrick; Hasan, Mohammad R; Coyle, Peter; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H; Latif, Ali N; Shaik, Riyazuddin M; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)Waning of vaccine protection against coronavirus disease 2019 (Covid-19) and the emergence of the omicron (or B.1.1.529) variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have led to expedited ... -
Effect of multiple freeze–thaw cycles on the detection of anti-SARS- CoV- 2 IgG antibodies
Shurrab, Farah M; Al-Sadeq, Duaa W.; Amanullah, Fathima; Younes, Salma N.; Al-Jighefee, Hadeel; Younes, Nadin; Dargham, Soha R.; Yassine, Hadi M.; Abu Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( Microbiology Society , 2021 , Article)Several studies have investigated the effect of repeated freeze-thaw (F/T) cycles on RNA detection for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). However, no data are available regarding the effect of ...