Browsing by Author "Smatti, Maria K."
Now showing items 21-40 of 47
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Smatti, Maria K.; Al-Sarraj, Yasser; Albagha, Omar; Yassine, Hadi M. ( Qatar University Press , 2020 , Poster)Background: Clinical outcomes of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed enormous inter-individual and inter-population differences, possibly ... -
Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.
Smatti, Maria K; Al-Sarraj, Yasser A; Albagha, Omar; Yassine, Hadi M ( Frontiers Media , 2020 , Article)Clinical outcomes of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed enormous inter-individual and inter-population differences, possibly due to host ... -
Immune Imprinting and Protection against Repeat Reinfection with SARS-CoV-2
Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Hasan, Mohammad R.; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Massachusetts Medical Society , 2022 , Other)More than 2 years into the coronavirus disease 2019 (Covid-19) pandemic, the global population carries heterogeneous immune histories derived from various exposures to infection, viral variants, and vaccination.1 Evidence ... -
Immune Modulatory Effects of Vitamin D on Viral Infections.
Siddiqui, Maheen; Manansala, Judhell S; Abdulrahman, Hana A; Nasrallah, Gheyath K; Smatti, Maria K; Younes, Nadin; Althani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( MDPI , 2020 , Article)Viral infections have been a cause of mortality for several centuries and continue to endanger the lives of many, specifically of the younger population. Vitamin D has long been recognized as a crucial element to the ... -
Improving Influenza Vaccination Rate among Primary Healthcare Workers in Qatar
Elawad, Khalid H; Farag, Elmoubasher A; Abuelgasim, Dina A; Smatti, Maria K; Al-Romaihi, Hamad E; Al Thani, Mohammed; Al Mujalli, Hanan; Shehata, Zienab; Alex, Merin; Al Thani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( MDPI , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ... -
Improving influenza vaccination rate among primary healthcareworkers in Qatar
Elawad, Khalid H.; Farag, Elmoubasher A.; Abuelgasim, Dina A.; Smatti, Maria K.; Al-Romaihi, Hamad E.; Al Thani, Mohammed; Al Mujalli, Hanan.; Shehata, Zienab; Alex, Merin; Al Thani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( MDPI AG , 2017 , Article)The purpose of this study was to improve influenza vaccination, and determine factors influencing vaccine declination among health care workers (HCW) in Qatar. We launched an influenza vaccination campaign to vaccinate ... -
Influenza Prevalence and Vaccine Efficacy in Diabetic Patients in Qatar
Thomas, Swapna; Smatti, Maria K.; Al Maslamani, Muna A.; Yassine, Hadi Mohamad ( Qatar University Press , 2021 , Poster)Introduction: Diabetes (DM) is often recognized as ?an independent risk factor for developing severe respiratory tract infections. Influenza infections are associated with higher hospitalization, morbidity and mortality ... -
Influenza, RSV, and Other Respiratory Infections among Children in Qatar
Smatti, Maria K.; Al-Romaihi, Hamad E.; Al-Khatib, Hebah A.; Coyle, Peter V.; Al Thani, Asmaa A.; Al Maslamani, Muna A; Yassine, Hadi M.... more authors ... less authors ( Qatar University Press , 2020 , Poster)Background: Acute respiratory infections (ARIs) lead to high rates of mortality and morbidity among children. However, studies on the etiology of respiratory infections among children in Qatar and surrounding countries are ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
Smatti, Maria K.; Nasrallah, Gheyath K.; Al Thani, Asmaa A.; Yassine, Hadi M. ( Elsevier , 2019 , Article)BackgroundGenerating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
Measuring influenza hemagglutinin (HA) stem-specific antibody-dependent cellular cytotoxicity (ADCC) in human sera using novel stabilized stem nanoparticle probes
Smatti, Maria K.; Nasrallah, Gheyath K.; Al Thani, Asmaa A.; Yassine, Hadi M. ( Elsevier , 2020 , Article)Background: Generating vaccine that confers a complete protection is a major goal in designing a universal influenza vaccine. Currently, there is a considerable interest in the broadly neutralizing antibodies (bnAb) targeting ... -
Mixed Viral-Bacterial Infections and Their Effects on Gut Microbiota and Clinical Illnesses in Children.
Mathew, Shilu; Smatti, Maria K; Al Ansari, Khalid; Nasrallah, Gheyath K; Al Thani, Asmaa A; Yassine, Hadi M... more authors ... less authors ( Nature Research , 2019 , Article)Acute gastroenteritis remains a major cause of morbidity and mortality among young children worldwide. It accounts for approximately 1.34 million deaths annually in children younger than five years. Infection can be caused ... -
Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012–2017)
Al-Romaihi, Hamad E.; Smatti, Maria K.; Al-Khatib, Hebah A.; Coyle, Peter V.; Ganesan, Nandakumar; Nadeem, Shazia; Farag, Elmoubasher A.; Al Thani, Asmaa A.; Al Khal, Abdullatif; Al Ansari, Khalid M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier B.V. , 2020 , Article)Background: Studies on the etiology of respiratory infections among children in Qatar and surrounding countries are limited. Objectives: To describe the prevalence and seasonality of RSV, influenza, and other respiratory ... -
Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Mestiri, Sarra; Merhi, Maysaloun; Inchakalody, Varghese P.; Taib, Nassiba; Smatti, Maria K.; Ahmad, Fareed; Raza, Afsheen; Ali, Fatma H.; Hydrose, Shereena; Fernandes, Queenie; Ansari, Abdul W.; Sahir, Fairooz; Al-Zaidan, Lobna; Jalis, Munir; Ghoul, Mokhtar; Allahverdi, Niloofar; Al Homsi, Mohammed U.; Uddin, Shahab; Jeremijenko, Andrew Martin; Nimir, Mai; Abu-Raddad, Laith J.; Abid, Fatma Ben; Zaqout, Ahmed; Alfheid, Sameer R.; Saqr, Hassan Mohamed Hassan; Omrani, Ali S.; Hssain, Ali Ait; Al Maslamani, Muna; Yassine, Hadi M.; Dermime, Said... more authors ... less authors ( Frontiers Media , 2023 , Article)Introduction: The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods: ... -
Predictive Biomarkers of Intensive Care Unit and Mechanical Ventilation Duration in Critically-Ill Coronavirus Disease 2019 Patients.
Taleb, Sara; Yassine, Hadi M; Benslimane, Fatiha M; Smatti, Maria K; Schuchardt, Sven; Albagha, Omar; Al-Thani, Asmaa A; Ait Hssain, Ali; Diboun, Ilhame; Elrayess, Mohamed A... more authors ... less authors ( Frontiers Media , 2021 , Article)Detection of early metabolic changes in critically-ill coronavirus disease 2019 (COVID-19) patients under invasive mechanical ventilation (IMV) at the intensive care unit (ICU) could predict recovery patterns and help in ... -
Prevalence and molecular profiling of Epstein Barr virus (EBV) among healthy blood donors from different nationalities in Qatar.
Smatti, Maria K; Yassine, Hadi M; AbuOdeh, Raed; AlMarawani, Asmaa; Taleb, Sara A; Althani, Asmaa A; Nasrallah, Gheyath K... more authors ... less authors ( Public Library of Science , 2017 , Article)The Epstein-Barr virus (EBV) is the causative agent of infectious mononucleosis. EBV is highly prevalent lymphotropic herpesvirus and has been linked to several malignancies. Transmission is generally by oral secretions, ... -
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Abdelrahman, Doua; Al-Sadeq, Duaa W.; Smatti, Maria K.; Taleb, Sara A.; AbuOdeh, Raed O.; Al-Absi, Enas S.; Al-Thani, Asmaa A.; Coyle, Peter. V.; Al-Dewik, Nader; Al Qahtani, Ahmed A.; Yassine, Hadi M.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2021 , Article)Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) ... -
Profiling of intestinal microbiota in patients infected with respiratory influenza a and b viruses
Al Khatib, Hebah A.; Mathew, Shilu; Smatti, Maria K.; Eltai, Nahla O.; Pathan, Sameer A.; Al Thani, Asmaa A.; Coyle, Peter V.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( MDPI , 2021 , Article)Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared the effect of influenza types, A and B, and influenza shedding in patients’ stools on ... -
Protection against Reinfection with the Omicron BA.2.75 Subvariant
Chemaitelly, Hiam; Tang, Patrick; Coyle, Peter; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Hasan, Mohammad R.; Ayoub, Houssein H.; Altarawneh, Heba N.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H.; Latif, Ali N.; Shaik, Riyazuddin M.; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed G.; Butt, Adeel A.; Al-Romaihi, Hamad E.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Massachusetts Medical Society , 2023 , Other)The BA.2.75 sublineage of the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may escape neutralizing antibodies. The BA.2.75 sublineage (primarily the BA.2.75.2 subvariant) ... -
Protection from previous natural infection compared with mRNA vaccination against SARS-CoV-2 infection and severe COVID-19 in Qatar: a retrospective cohort study
Hiam, Chemaitelly; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Elsevier , 2022 , Article)BackgroundUnderstanding protection conferred by natural SARS-CoV-2 infection versus COVID-19 vaccination is important for informing vaccine mandate decisions. We compared protection conferred by natural infection versus ... -
Protection of Omicron sub-lineage infection against reinfection with another Omicron sub-lineage
Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; Al-Khatib, Hebah A.; Smatti, Maria K.; Hasan, Mohammad R.; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F.; Nasrallah, Gheyath K.; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A.; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J.... more authors ... less authors ( Nature Research , 2022 , Article)There is significant genetic distance between SARS-CoV-2 Omicron (B.1.1.529) variant BA.1 and BA.2 sub-lineages. This study investigates immune protection of infection with one sub-lineage against reinfection with the other ...