Browsing by Subject "Actin"

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    • KRAP tethers IP3 receptors to actin and licenses them to evoke cytosolic Ca2+ signals 

      Thillaiappan, Nagendra Babu; Smith, Holly A.; Atakpa-Adaji, Peace; Taylor, Colin W. ( Nature Research , 2021 , Article)
      Regulation of IP3 receptors (IP3Rs) by IP3 and Ca2+ allows regenerative Ca2+ signals, the smallest being Ca2+ puffs, which arise from coordinated openings of a few clustered IP3Rs. Cells express thousands of mostly mobile ...