Medicine Research: Recent submissions

Now showing items 1-20 of 1344

    • Urinary guide-wire and Tritube solved the mystery of severe tracheal stenosis management: A case report 

      Muhammad Firas., Alhammad; Mathias, Ranjan; Nahid, Seema; Fernando, Roshan; Zaki, Hany A.; ... more authors ( Elsevier , 2023 , Article)
      Patients with tracheal stenosis may exhibit various signs and symptoms of respiratory compromise, depending on the degree of stenosis. Proper identification and prompt intervention are crucial to ensure the best possible ...

    • Subclavian pseudoaneurysm presenting as partially obstructed airway 

      Muhammad J., Khan; Alhammad, Muhammad F.; Kassas, Hazim A.; Hammad, Yasser A.; El-Khatib, Mohamed S.; ... more authors (2023 , Article)
      We are presenting a noteworthy instance of managing the airway of a patient who had acute tracheal stenosis of considerable magnitude caused by external compression resulting from a large right subclavian pseudoaneurysm.Tracheal ...

    • Non-Participatory Observation Of Integrated Management Of Childhood Illness Practices At Selected Basic Health Units Of District Abbottabad, Kp, Pakistan: A Qualitative Hermeneutic Study 

      Abrar, Saidul; Hafeez, Assad; Khan, Muhammad Naseem; Rahim, Sana; Ali, Yasir; ... more authors ( Ayub Medical College , 2023 , Article)
      BACKGROUND: It was in 1995 when a strategy was devised to reduce under-five mortality in countries with a prevalence of child mortality above 40/1000 live births. This strategy is called "Integrated Management of Childhood ...

    • Bioelectrical Impedance Analysis Detects Body Fat Changes After Surgical Subcutaneous Fat Removal 

      Ahmed, Mohamed Badie; Doi, Suhail A.; Habib, Abdella M.; Glass, Graeme E.; Hammouda, Atalla; ... more authors ( Mary Ann Liebert , 2024 , Article)
      Background: The risk and metabolic effects of obesity are determined by the distribution of fat throughout the body. It has been proposed that the distribution of abdominal fat is more closely related to the metabolic risks ...

    • Comprehensive molecular and clinical insights into non-small cell lung cancer transformation to small cell lung cancer with an illustrative case report 

      Tomic, Kresimir; Krpina, Kristina; Baticic, Lara; Samarzija, Miroslav; Vranic, Semir ( Taylor & Francis , 2024 , Article)
      Histologic transformation to small cell lung cancer (tSCLC) is a rare but increasingly recognised mechanism of acquired resistance to tyrosine kinase inhibitors (TKI) in patients with epidermal growth factor receptor ...

    • Perspectives of healthcare workers on integrated management of childhood illness in Pakistan: A phenomenological approach 

      Abrar, Saidul; Hafeez, Asad; Khan, Muhammad Naseem; Marwat, Muhammad Imran ( SAGE , 2024 , Article)
      In 2019, an estimated 5.2 million deaths were reported among children less than 5 years of age. At primary healthcare level, healthcare workers (HCWs) mostly rely on history and clinical findings and less on inadequate ...

    • Low levels of Vitamin D during pregnancy associated with gestational diabetes mellitus and low birth weight: results from the MAASTHI birth cohort 

      Deepa, R.; Van Schayck, Onno C. P.; Babu3, Giridhara R. ( Frontiers Media , 2024 , Article)
      Introduction: India has a high prevalence of Vitamin D insufficiency among women of childbearing age. In this study, we aimed to evaluate the potential relationship between Vitamin D deficiency and gestational diabetes ...

    • Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure 

      Saleh, Alaaeldin; Thanassoulas, Angelos; Aliyev, Elnur; Swann, Karl; Naija, Azza; ... more authors ( MDPI , 2024 , Article)
      The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca2+ release responsible for oocyte activation during mammalian fertilization. The ...

    • The relationship between oxidative stress and apoptosis of histopathological changes in the ovary made by mad honey containing grayanotoxin 

      Yeşil Sarsmaz, Hayrunnisa; Gürgen, Seren Gülşen; Cansu, Ali; Türkmen, Süha; Gündüz, Abdülkadir ( Elsevier , 2024 , Article)
      The purpose of this study is to determine the effects of grayanotoxin in mad honey on ovarian tissue folliculogenesis in terms of cell death and nitric oxide expression. Three groups of 18 female Sprague-Dawley rats were ...

    • Injuries related to pets, exotic animals, and falconry in Qatar 

      urkmen, Suha; Alinier, Guillaume; Elmoheen, Amr Mohammed; Qureshi, Alamgir Ahmed; Ponappan, Benny Remi; ... more authors ( HBKU Press , 2023 , Article)
      Introduction: Pets and exotic animals are increasingly popular all over the world. Some of these animals may cause injuries to their owners or other people during interactions. Both injuries and systemic infections always ...

    • The cost associated with the development of the antimicrobial stewardship program in the adult general medicine setting in Qatar 

      Abushanab, Dina; AL-Marridi, Wafa; Al Hail, Moza; Abdul Rouf, Palli Valappila; ElKassem, Wessam; ... more authors ( Taylor and Francis Ltd. , 2024 , Article)
      Objective: To estimate the economic impact of the developed antimicrobial stewardship program (ASP) versus the preliminary ASP use, in the adults' general medicine settings in Qatar. Methods: Patient records were retrospectively ...

    • Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 

      Stein Emil, Vollset; Ababneh, Hazim S; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ...

    • Prevalence of dyslipidemia, hypertension and diabetes among tribal and rural population in a south Indian forested region. 

      Mallikarjuna Majgi, Sumanth; Channa Basappa, Yogish; Belagihalli Manjegowda, Srikanta; Nageshappa, Savitha; Suresh, Harshini; ... more authors ( Public Library of Science , 2024 , Article)
      While NCDs are in rise globally, tribal and rural populations residing near to reserve forests with limited exposure to modern lifestyles may bear a unique burden. This study investigates the prevalence and risk factors ...

    • SARS-CoV-2 infection triggers more potent antibody-dependent cellular cytotoxicity (ADCC) responses than mRNA-, vector-, and inactivated virus-based COVID-19 vaccines 

      Zedan, Hadeel T.; Smatti, Maria K.; Al-Sadeq, Duaa W.; Al Khatib, Hebah A.; Nicolai, Eleonora; ... more authors ( Wiley , 2024 , Article)
      Neutralizing antibodies (NAbs) are elicited after infection and vaccination and have been well studied. However, their antibody-dependent cellular cytotoxicity (ADCC) functionality is still poorly characterized. Here, we ...

    • Follow-Up and Comparative Assessment of SARS-CoV-2 IgA, IgG, Neutralizing, and Total Antibody Responses After BNT162b2 or mRNA-1273 Heterologous Booster Vaccination 

      Younes, Salma; Nicolai, Eleonora; Pieri, Massimo; Bernardini, Sergio; Daas, Hanin I; ... more authors ( Wiley , 2024 , Article)
      Background: Priming with ChAdOx1 followed by heterologous boosting is considered in several countries. Nevertheless, analyses comparing the immunogenicity of heterologous booster to homologous primary vaccination regimens ...

    • Pathogenic Homocystinuria-Associated T236N Mutation Dramatically Alters the Biochemical Properties of Cystathionine Beta-Synthase Protein 

      Al-Sadeq, Duaa W.; Thanassoulas, Angelos; Theodoridou, Maria; Nasrallah, Gheyath K.; Nomikos, Michail ( MDPI , 2024 , Article)
      Background: Cystathione beta-synthase (CBS) T236N is a novel mutation associated with pyridoxine non-responsiveness, which presents a significant difficulty in the medical treatment of homocystinuria. Reported severe ...

    • Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens 

      Thomas, Swapna; Smatti, Maria K.; Alsulaiti, Haya; Zedan, Hadeel T.; Eid, Ali H.; ... more authors ( Wiley , 2024 , Article)
      This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ...

    • Cranial measurements obtained by three-dimensional computed tomography technique in the estimation of sex of contemporary Black South Africans 

      Oriasotie M, Ujaddughe; Haberfeld, Jenny; Bidmos, Mubarak A; Olateju, Oladiran I ( Elsevier , 2024 , Article)
      Human identification forms an integral part of forensic and biological anthropology. For proper identification, a biological profile made up of biodata such as age, sex, ancestry, antemortem stature, and factors of ...

    • BRCA1 and Its Vulnerable C-Terminal BRCT Domain: Structure, Function, Genetic Mutations and Links to Diagnosis and Treatment of Breast and Ovarian Cancer 

      Ismail, Tala; Alzneika, Safa; Riguene, Emna; Al-maraghi, Salwa; Alabdulrazzak, Aya; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)
      The BRCA1 is a tumor suppressor gene that encodes for the BRCA1 protein, which plays a vital role in DNA repair, cell cycle regulation, and the maintenance of genomic stability. The BRCA1 protein interacts with a variety ...

    • Efficacy and Clinical Outcomes of mRNA COVID-19 Vaccine in Pregnancy: A Systematic Review and Meta-Analysis 

      Santimano, Antonio J.; Al-Zoubi, Raed M.; Al-Qudimat, Ahmad R.; Al Darwish, Mohamed B.; Ojha, Laxmi Kumari; ... more authors ( S. Karger AG , 2024 , Article)
      BACKGROUND: The world has witnessed one of the largest pandemics, dubbed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of December 2020, the USA alone reported 98,948 cases of coronavirus disease 2019 ...