Browsing Pharmacy Research by Title
Now showing items 788-807 of 1225
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Naturally-Occurring Bioactives in Oral Cancer: Preclinical and Clinical Studies, Bottlenecks and Future Directions
( IMR Press Limited , 2022 , Article)Oral cancer (OC) is the eighth most common cancer, particularly prevalent in developing countries. Current treatment includes a multidisciplinary approach, involving chemo, radio, and immunotherapy and surgery, which depends ... -
Needs Assessments approaches to inform Continuous Professional Development for Health Professionals: A Scoping Systematic Review
( Qatar University Press , 2021 , Poster)The need for continuing professional development (CPD) within the healthcare profession is well established. A rigorous learning need assessment (LNA) is a crucial initial step in the CPD process. Given the scarcity of the ... -
Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway
( Wiley-Blackwell , 2023 , Article)Multiple myeloma (MM) is a hematologic malignancy associated with malignant plasma cell proliferation in the bone marrow. Despite the available treatments, drug resistance and adverse side effects pose significant challenges, ... -
Nephroprotective Effects of Metformin in Diabetic Nephropathy
( Wiley , 2017 , Article)Metformin, a well-known anti-diabetic agent, is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side-effects. Metformin is also being recommended in the treatment of obesity and ... -
Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer
( Frontiers Media SA , 2024 , Article)In the current study, Neosetophomone B (NSP-B) was investigated for its anti-cancerous potential using network pharmacology, quantum polarized ligand docking, molecular simulation, and binding free energy calculation. Using ... -
New three-dimensional poly(decanediol-co-tricarballylate) elastomeric fibrous mesh fabricated by photoreactive electrospinning for cardiac tissue engineering applications
( MDPI AG , 2018 , Article)Reactive electrospinning is capable of efficiently producing in situ crosslinked scaffolds resembling the natural extracellular matrix with tunable characteristics. In this study, we aimed to synthesize, characterize, and ... -
NICU Medication Errors: Describing the Cause and Nature of Medication Errors in a NICU in Qatar
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference Paper)Introduction: A medication error can be defined as "any error occurring in the medication use process" and focuses on problems with the delivery of medication to a patient [1]. Medication errors are a complex and ongoing ... -
A non-clinical randomised controlled trial to assess the impact of pharmaceutical care intervention on satisfaction level of newly diagnosed diabetes mellitus patients in a tertiary care teaching hospital in Nepal
( BioMed Central , 2015 , Article)Background Patient satisfaction is the ultimate goal of healthcare system which can be achieved from good patient-healthcare professional relationship and quality of healthcare services provided. Study was conducted ... -
Norfloxacin loaded lipid polymer hybrid nanoparticles for oral administration: Fabrication, characterization, in silico modelling and toxicity evaluation
( MDPI , 2021 , Article)Norfloxacin (NOR), widely employed as an anti-bacterial drug, has poor oral bioavailability. Nano based drug delivery systems are widely used to overcome the existing oral bioavailability challenges. Lipid–Polymer Hybrid ... -
A novel approach of encapsulating curcumin and succinylated derivative in mannosylated-chitosan nanoparticles
( Elsevier , 2022 , Article)Curcumin (CUR) manifests anti-colon cancer activity but suffers from low solubility, bioavailability, and instability, rendering it not as effective as its chemotherapeutic cousins. Here, we conjugate CUR to succinic ... -
Novel nitrogen-based chalcone analogs provoke substantial apoptosis in HER2-positive human breast cancer cells via JNK and ERK1/ERK2 signaling pathways
( MDPI , 2021 , Article)Natural chalcones possess antitumor properties and play a role as inducers of apoptosis, antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone-based compounds, which were generated in our ... -
Novel oral formulations of metformin in semi-solid matrices: Design, characterization and in vitro dissolution testing
( Hamad bin Khalifa University Press (HBKU Press) , 2012 , Conference Paper)Objectives: To formulate and evaluate oral dosage forms of metformin hydrochloride (MH) having sustained-release properties that would also increase MH bioavailability and address the shortcomings in the currently marketed ... -
Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines
( Elsevier, Ltd , 2016 , Article)The aim of this study is to investigate using nanoemulsion formulations as drug-delivery vehicles of paclitaxel (PX), a poor water-soluble anticancer drug. Two commercially available nanoemulsion fat formulations (Clinoleic ... -
Novel poly (diol-co-tricarballylate) implantable elastomeric matrices: Long term biocompatibility and biodegradation studies
(2011 , Conference Paper)N/A. -
Novel polymethoxylated chalcones as potential compounds against kras-mutant colorectal cancers
( Bentham Science Publishers , 2020 , Article)Background/Objective: KRAS-mutant colorectal cancers (CRC) are tumors that are associated with poor prognosis. However, no effective treatments are available to target them. Therefore, we designed and synthesized novel ... -
Nurses’ perceptions of and satisfaction with the use of automated dispensing cabinets at the Heart and Cancer Centers in Qatar: a cross-sectional study
( BioMed Central , 2016 , Article)Background Automated dispensing cabinets (ADCs) were introduced in 2010 and 2012 at the Heart Hospital (HH) and National Center for Cancer Care and Research (NCCCR), both run by Hamad Medical Corporation in Qatar. These ... -
Obesity Paradox among Heart Failure with Reduced Ejection Fraction Patients: A Retrospective Cohort Study
( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background and Objectives: There is consensus on the negative effects of obesity on the development of heart failure. However, several studies have suggested that obesity may have paradoxical survival benefits in heart ... -
Obesity-induced changes in kidney mitochondria and endoplasmic reticulum in the presence or absence of leptin
( American Physiological Society , 2015 , Article)We investigated obesity-induced changes in kidney lipid accumulation, mitochondrial function, and endoplasmic reticulum (ER) stress in the absence of hypertension, and the potential role of leptin in modulating these ... -
Objective structured clinical examination for pharmacy students in Qatar: cultural and contextual barriers to assessment.
( World Health Organization , 2016 , Article)This study aimed to evaluate the feasibility and psychometric defensibility of implementing a comprehensive objective structured clinical examination (OSCE) on the complete pharmacy programme for pharmacy students in a ... -
Obstructive sleep apnea: Management considerations in psychiatric patients
( Dove Press , 2015 , Article)Psychiatric disorders and obstructive sleep apnea (OSA) are often comorbid. However, there is limited information on the impact of psychotropic medications on OSA symptoms, on how to manage psychiatric pharmacotherapy in ...