تصفح Biomedical Research Center Research حسب المؤلف "Uddin, Shahab"
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Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
Fernandes, Queenie; Inchakalody, Varghese Philipose; Merhi, Maysaloun; Mestiri, Sarra; Taib, Nassiba; Moustafa Abo El-Ella, Dina; Bedhiafi, Takwa; Raza, Afsheen; Al-Zaidan, Lobna; Mohsen, Mona O.; Yousuf Al-Nesf, Mariam Ali; Hssain, Ali Ait; Yassine, Hadi Mohamad; Bachmann, Martin F.; Uddin, Shahab; Dermime, Said... more authors ... less authors ( Taylor and Francis , 2022 , Article)The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for change in the form of newer and more adaptive diagnostic methods for the detection of SARS-CoV-2 infections. On the other hand, developing ... -
Inhibition of p90 ribosomal S6 kinase potentiates cisplatin activity in A549 human lung adenocarcinoma cells
Abdulrahman, Nabeel; Siveen, Kodappully Sivaraman; Joseph, Jensa Mariam; Osman, Aisha; Yalcin, Huseyin C.; Hasan, Anwarul; Uddin, Shahab; Mraiche, Fatima... more authors ... less authors ( Wiley , 2020 , Article)© 2020 Royal Pharmaceutical Society Aim: Cisplatin is a standard treatment approach against lung adenocarcinoma. Resistance to cisplatin and the toxic side effects of cisplatin continue to remain a challenge. Combining ... -
Persistence of spike-specific immune responses in BNT162b2-vaccinated donors and generation of rapid ex-vivo T cells expansion protocol for adoptive immunotherapy: A pilot study
Mestiri, Sarra; Merhi, Maysaloun; Inchakalody, Varghese P.; Taib, Nassiba; Smatti, Maria K.; Ahmad, Fareed; Raza, Afsheen; Ali, Fatma H.; Hydrose, Shereena; Fernandes, Queenie; Ansari, Abdul W.; Sahir, Fairooz; Al-Zaidan, Lobna; Jalis, Munir; Ghoul, Mokhtar; Allahverdi, Niloofar; Al Homsi, Mohammed U.; Uddin, Shahab; Jeremijenko, Andrew Martin; Nimir, Mai; Abu-Raddad, Laith J.; Abid, Fatma Ben; Zaqout, Ahmed; Alfheid, Sameer R.; Saqr, Hassan Mohamed Hassan; Omrani, Ali S.; Hssain, Ali Ait; Al Maslamani, Muna; Yassine, Hadi M.; Dermime, Said... more authors ... less authors ( Frontiers Media , 2023 , Article)Introduction: The BNT162b2 mRNA-based vaccine has shown high efficacy in preventing COVID-19 infection but there are limited data on the types and persistence of the humoral and T cell responses to such a vaccine. Methods: ... -
The Role of p90 Ribosomal S6 Kinase (RSK) in Tyrosine Kinase Inhibitor (TKI)-Induced Cardiotoxicity
Suleiman, Muna; Al Najjar, Afnan; Zakaria, Zain Z.; Ahmed, Rashid; Yalcin, Huseyin C.; Korashy, Hesham M.; Uddin, Shahab; Riaz, Sadaf; Abdulrahman, Nabeel; Mraiche, Fatima... more authors ... less authors ( Springer , 2023 , Article Review)Targeted therapy, such as tyrosine kinase inhibitors (TKIs), has been approved to manage various cancer types. However, TKI-induced cardiotoxicity is a limiting factor for their use. This issue has raised the need for ...