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    • Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives 

      Cao, Yanyan; Himmeldirk, Klaus B.; Qian, Yanrong; Ren, Yulin; Malki, Ahmed; ... more authors ( Springer Nature , 2014 , Other)
      Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous ...

    • Blood Homocysteine Levels Mediate the Association Between Blood Lead Levels and Cardiovascular Mortality 

      Shibeeb, Sapha; Abdallah, Atiyeh; Shi, Zumin ( Springer Nature , 2024 , Article)
      Lead is a heavy, toxic metal and its exposure to humans can lead to increased risk of cardiovascular disease development and mortality. Lead exposure has been shown to induce hyperhomocysteinemia (HHCy) which may be a major ...

    • Can absence of cardiac activity on point-of-care echocardiography predict death in out-of-hospital cardiac arrest? A systematic review and meta-analysis 

      Albaroudi, Omar; Albaroudi, Bilal; Haddad, Mahmoud; Abdle-Rahman, Manar E.; Kumar, Thirumoothy Samy Suresh; ... more authors ( Springer Nature , 2024 , Article Review)
      Aim: The purpose of this systematic review and meta-analysis was to evaluate the accuracy of the absence of cardiac motion on point-of-care echocardiography (PCE) in predicting termination of resuscitation (TOR), short-term ...

    • Characterizing trends and associations for hepatitis C virus antibody prevalence in the Middle East and North Africa: meta-regression analyses 

      Mahmud, Sarwat; Chemaitelly, Hiam; Alaama, Ahmed S.; Hermez, Joumana G.; Abu-Raddad, Laith J. ( Springer Nature , 2022 , Article)
      This study characterized population-level trends and associations with hepatitis C virus (HCV) antibody (Ab) prevalence in the Middle East and North Africa (MENA). Data source was the standardized and systematically gathered ...

    • Children’s and adolescents’ rising animal-source food intakes in 1990–2018 were impacted by age, region, parental education and urbanicity 

      Miller, Victoria; Webb, Patrick; Cudhea, Frederick; Zhang, Jianyi; Reedy, Julia; ... more authors ( Springer Nature , 2023 , Article)
      Animal-source foods (ASF) provide nutrition for children and adolescents’ physical and cognitive development. Here, we use data from the Global Dietary Database and Bayesian hierarchical models to quantify global, regional ...

    • Computational design of anti-cancer peptides tailored to target specific tumor markers 

      Naeem, Aisha; Noureen, Nighat; Al-Naemi, Shaikha Khalid; Al-Emadi, Jawaher Ahmed; Khan, Muhammad Jawad ( Springer Nature , 2024 , Article)
      Anti-cancer peptides (ACPs) are short peptides known for their ability to inhibit tumor cell proliferation, migration, and the formation of tumor blood vessels. In this study, we designed ACPs to target receptors often ...

    • Dietary patterns and cardiovascular disease risk among Chinese adults: a prospective cohort study 

      Shi, Zumin; Ganji, Vijay ( Springer Nature , 2020 , Article)
      Background and objective We aimed to examine the prospective association between dietary patterns and cardiovascular disease (CVD) risk in Chinese adults. Methods Adults aged ≥20 years in the China Health and Nutrition ...

    • Diminishing benefits of urban living for children and adolescents’ growth and development 

      Mishra, Anu; Zhou, Bin; Rodriguez-Martinez, Andrea; Bixby, Honor; Singleton, Rosie K.; ... more authors ( Springer Nature , 2023 , Article)
      Optimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million ...

    • Elevated serum leptin levels in patients with acute myocardial infarction; Correlation with coronary angiographic and echocardiographic findings 

      Khafaji, Hadi A.R.Hadi; Bener, Abdul Bari; Rizk, Nasser M.; Al Suwaidi, Jassim ( Springer Nature , 2012 , Article)
      Background: To assess the relationship between serial serum leptin levels in patients with acute myocardial infarction (AMI) who received thrombolysis and the degree of coronary atherosclerosis, coronary reperfusion, ...

    • Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease 

      Sundarrajan, Sudharsana; Venkatesan, Arthi; Kumar S, Udhaya; Gopikrishnan, Mohanraj; Tayubi, Iftikhar Aslam; ... more authors ( Springer Nature , 2023 , Article)
      Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. A steep rise in AD incidents is observed in the elderly population in East-Asian countries. ...

    • Fast food and sweet intake pattern is directly associated with the prevalence of asthma in a Qatari population 

      Shi, Zumin; El-Obeid, Tahra; Meftah, Zainab; Alawi, Amal; Said, Suad; ... more authors ( Springer Nature , 2021 , Article)
      Objective The relationship between dietary patterns and the prevalence of asthma is not well understood. We aimed to investigate the association between dietary patterns and asthma in adults in Qatar. Methods In this ...

    • The genetic basis and the diagnostic yield of genetic testing related to nonsyndromic hearing loss in Qatar 

      Alkhidir, Shaza; El-Akouri, Karen; Al-Dewik, Nader; Khodjet-El-khil, Houssein; Okashah, Sarah; ... more authors ( Springer Nature , 2024 , Article)
      Hearing loss is the most predominant sensory defect occurring in pediatrics, of which, 66% cases are attributed to genetic factors. The prevalence of hereditary hearing loss increases in consanguineous populations, and the ...

    • Genetic polymorphisms associated with obesity in the Arab world: a systematic review 

      Younes, Salma; Ibrahim, Amal; Al-Jurf, Rana; Zayed, Hatem ( Springer Nature , 2021 , Article Review)
      Background: Obesity, one of the most common chronic health conditions worldwide, is a multifactorial disease caused by complex genetic and environmental interactions. Several association studies have revealed a considerable ...

    • Imaging Patterns in Breast Cancer for Women Under 40 Years: A Descriptive Cohort Study 

      Alhaidary, Amal A.; Al-Qudimat, Ahmad R.; Arabi, Haitham; Al-Zoubi, Raed M. ( Springer Nature , 2024 , Article)
      Background and Aim: Breast cancer is the most frequently occurring malignant disease in women and remains the leading cause of cancer-related deaths among females worldwide. The aim of this study is to evaluate the imaging ...

    • Incident type 2 diabetes attributable to suboptimal diet in 184 countries 

      O’Hearn, Meghan; Lara-Castor, Laura; Cudhea, Frederick; Miller, Victoria; Reedy, Julia; ... more authors ( Springer Nature , 2023 , Article)
      The global burden of diet-attributable type 2 diabetes (T2D) is not well established. This risk assessment model estimated T2D incidence among adults attributable to direct and body weight-mediated effects of 11 dietary ...

    • The influence of adolescents essential and non-essential use of technology and Internet addiction on their physical and mental fatigues 

      Aziz, Maryam; Chemnad, Khansa; Al-Harahsheh, Sanaa; Abdelmoneium, Azza O.; Bagdady, Ahmed; ... more authors ( Springer Nature , 2024 , Article)
      This study explores the impact of Internet addiction (IA), age, and essential and non-essential technology usage time on the physical and mental fatigue of adolescents. The research surveyed 477 adolescents from Qatar and ...

    • Machine learning techniques for the identification of risk factors associated with food insecurity among adults in Arab countries during the COVID-19 pandemic 

      Qasrawi, Radwan; Hoteit, Maha; Tayyem, Reema; Bookari, Khlood; Al Sabbah, Haleama; ... more authors ( Springer Nature , 2023 , Article)
      Background: A direct consequence of global warming, and strongly correlated with poor physical and mental health, food insecurity is a rising global concern associated with low dietary intake. The Coronavirus pandemic has ...

    • Neutralization of MERS coronavirus through a scalable nanoparticle vaccine 

      Mohsen, Mona O; Rothen, Dominik; Balke, Ina; Martina, Byron; Zeltina, Vilija; ... more authors ( Springer Nature , 2021 , Article)
      MERS-CoV continues to cause human outbreaks, so far in 27 countries worldwide following the first registered epidemic in Saudi Arabia in 2012. In this study, we produced a nanovaccine based on virus-like particles (VLPs). ...

    • Prevalence of hepatitis B and C viruses among migrant workers in Qatar. 

      Nasrallah, Gheyath K; Chemaitelly, Hiam; Ismail, Ahmed I A; Nizamuddin, Parveen B; Al-Sadeq, Duaa W; ... more authors ( Springer Nature , 2024 , Article)
      Limited data exist on viral hepatitis among migrant populations. This study investigated the prevalence of current hepatitis B virus (HBV) infection and lifetime hepatitis C virus (HCV) infection among Qatar's migrant craft ...

    • Prevalence, knowledge, awareness, and attitudes towards dietary supplements among Bahraini adults: a cross-sectional study 

      Allehdan, Sabika; Hasan, Mariam; Perna, Simone; Al-Mannai, Mariam; Alalwan, Tariq; ... more authors ( Springer Nature , 2023 , Article)
      The usage of dietary supplements (DS) is a global trend that is likely influenced by sociodemographic variables and body weight status. Some individuals utilize supplements in the hopes that they may enhance their health ...