Browsing College of Health Sciences by Subject "Zebrafish"
Now showing items 1-12 of 12
-
Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, physicochemical and neurological study profile.
( Elsevier , 2019 , Article)Clinically approved iron chelators are effective in decreasing significant transfusional iron accumulation. Starch-Deferoxamine (S-DFO), a novel high molecular weight iron chelator, was produced to increase binding capacity ... -
Combine iron Chelation therapy ameliorates decline of iron on iron loaded Zebrafish embryo
(2017 , Conference Proceedings)Thalassemia is the most common genetically inherited blood disorder in the world arisen from defect in hemoglobin production, resulting in ineffective erythropoiesis and rapid destruction of RBC in the periphery that ... -
Development and In Vivo Testing of Smart Nanoparticles for Enhanced Anti-Cancer Activity and Reduced Cardiotoxicity Associated with Tyrosine Kinase Inhibitors
( Qatar University Press , 2021 , Poster)Tyrosine kinase inhibitors (TKIs) are new generation of anti-cancer drugs with very high efficiency against cancer cells. However, TKIs are associated with severe cardiotoxicity limiting their clinical benefits. One TKI ... -
Ecotoxicity and environmental safety assessment of two-dimensional niobium carbides (MXenes)
( Elsevier , 2024 , Article)Two-dimensional (2D) MXenes have gained great interest in water treatment, biomedical, and environmental applications. The antimicrobial activity and cell toxicity of several MXenes including Nb4C3Tx and Nb2CTx have already ... -
Ecotoxicological assessment of Ti3C2Tx (MXene) using a zebrafish embryo model
( Royal Society of Chemistry , 2018 , Article)The recent application of 2D Ti3C2Tx (MXene) nanomaterials as adsorbents and membranes for water treatment as well as for biomedical applications is attracting a growing interest. However, the environmental impact of MXene ... -
Ecotoxicological assessment of two surfactant on the emryonic development
( Qatar University Press , 2021 , Poster)In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 ... -
Human c-MYBPC3 RNA Targeted Therapy, Reversal of Hypertrophic Cardiomyopathy in the Zebrafish Model
( Qscience. , 2016 , Conference Paper)Hypertrophic cardiomyopathy (HCM) is a serious heart disease and is defined as abnormal left ventricular (LV) wall thickening with diastolic dysfunction. HCM is an autosomal dominant monogenic disease caused by a mutation ... -
In vivo testing of novel nitric oxide-releasing nanoparticles for alleviating heart failure using the zebrafish embryo model
( Elsevier , 2024 , Article)Heart failure (HF) is a multifactorial, heterogeneous systemic disease that is considered one of the leading causes of death and morbidity worldwide. It is well-known that endothelial dysfunction (ED) plays an important ... -
Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos
( Elsevier , 2020 , Article)Surfactants are widely used in the industry of detergents, household products, and cosmetics. SAPDMA is a cationic surfactant that is used mostly in cosmetics, conditioning agents and has recently gained attention as a ... -
Solar cultivation of microalgae in a desert environment for the development of techno-functional feed ingredients for aquaculture in Qatar
( Elsevier , 2022 , Article)The demand for aquaculture feed will increase in the coming years in order to ensure food security for a growing global population. Microalgae represent a potential fish-feed ingredient; however, the feasibility of their ... -
Toxicity evaluation of selected ionic liquid compounds on embryonic development of Zebrafish.
( Elsevier , 2018 , Article)Hydrate formation in seafloor pipelines is considered an economic and flow assurance issue for the oil and gas industries. Ionic liquids (ILs) have been recently used as potential hydrate inhibitors. Although branded as ... -
Zebrafish (Danio rerio) as a Model for the Study of Developmental and Cardiovascular Toxicity of Electronic Cigarettes
( MDPI , 2023 , Article Review)The increasing popularity of electronic cigarettes (e-cigarettes) as an alternative to conventional tobacco products has raised concerns regarding their potential adverse effects. The cardiovascular system undergoes intricate ...
