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INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
(Health Sciences, 2015 , Master Thesis)
Obesity has been associated with chronic low-grade inflammation, which is
considered to be a major cause for insulin resistance and type 2 diabetes (T2D). The
therapeutic interventions for T2D are lacking due to the ...
Effect of hypoxia on metabolic markers and gene expression HIF-1 α in adipocytes
(Health Sciences, 2015 , Master Thesis)
Background: Docosahexaenoic acid (DHA; omega-3 fatty acid) has been reported to have potential anti-obesity properties. Hypoxia is a condition that results from the excessive expansion of white adipose tissue resulting in ...
The Regulation of BRN3B in Adipocytes by Glucose and Insulin
(Health Sciences, 2014 , Master Thesis)
Obesity is the inappropriate accumulation of excess fat stored in the adipocytes of the adipose tissue. Understanding the molecular mechanisms that regulate the process of the preadipocyte to adipocyte conversion, adipogenesis, ...
Brn-3b and PPARy Nuclear Receptor Expression in Adipose Tissue of Human Subjects
(Health Sciences, 2014 , Master Thesis)
Obesity rates have reached alarming heights globally, having more than doubled since the 1980's. Over 60% of diabetic patients are obese, and the increasing severity of the disease is associated with Type 2 Diabetes ...