Browsing Biomedical Research Center by Author "Ouhtit, Allal"
Now showing items 1-7 of 7
-
Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
Thomas, Swapna; Smatti, Maria K.; Ouhtit, Allal; Cyprian, Farhan S.; Almaslamani, Muna A.; Al Thani, Asmaa; Yassine, Hadi M.... more authors ... less authors ( Elsevier Ltd , 2022 , Article Review)Antibody-dependent enhancement (ADE) has been associated with severe disease outcomes in several viral infections, including respiratory infections. In vitro and in vivo studies showed that antibody-response to SARS-CoV ... -
Antibody-dependent enhancement (ADE) of SARS-CoV-2 in patients exposed to MERS-CoV and SARS-CoV-2 antigens
Thomas, Swapna; Smatti, Maria K.; Alsulaiti, Haya; Zedan, Hadeel T.; Eid, Ali H.; Hssain, Ali A.; Abu Raddad, Laith J.; Gentilcore, Giusy; Ouhtit, Allal; Althani, Asmaa A.; Nasrallah, Gheyath K.; Grivel, Jean Charles; Yassine, Hadi M.... more authors ... less authors ( Wiley , 2024 , Article)This study evaluated the potential for antibody-dependent enhancement (ADE) in serum samples from patients exposed to Middle East respiratory syndrome coronavirus (MERS-CoV). Furthermore, we evaluated the effect of severe ... -
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Swapna, Thomas; Ouhtit, Allal; Al Khatib, Hebah A.; Eid, Ali H.; Mathew, Shilu; Nasrallah, Gheyath K.; Emara, Mohamed M.; Al Maslamani, Muna A.; Yassine, Hadi M.... more authors ... less authors ( Elsevier , 2022 , Article Review)Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and type 2 diabetes has increased rapidly and has become one of the leading ... -
Haematococcus pluvialis Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells
Alateyah, Nouralhuda; Ahmad, Salma M. S.; Gupta, Ishita; Fouzat, Arij; Thaher, Mahmoud Ibrahim; Das, Probir; Al Moustafa, Ala-Eddin; Ouhtit, Allal... more authors ... less authors ( Frontiers Media S.A. , 2022 , Article)Breast cancer (BC) is the most common malignant cancer in females worldwide. Drug resistance, toxicity, and the failure of current therapies to completely cure BC has challenged conventional medicine. Consequently, ... -
Novel CD44-downstream signaling pathways mediating breast tumor invasion
Ouhtit, Allal; Rizeq, Balsam; Abou Saleh, Haissam; Rahman, MD Mizanur; Zayed, Hatem ( Ivyspring International Publisher , 2018 , Article Review)CD44, also known as homing cell adhesion molecule is a multi-structural cell molecule involved in cell-cell and cell-extracellular matrix communications. CD44 regulates a number of central signaling pathways, including ... -
Nox2 activity is required in obesity-mediated alteration of bone remodeling
Rahman, Md Mizanur; El Jamali, Amina; Halade, Ganesh V.; Ouhtit, Allal; Abou-Saleh, Haissam; Pintus, Gianfranco... more authors ... less authors ( Hindawi Limited , 2018 , Article)Despite increasing evidence suggesting a role for NADPH oxidases (Nox) in bone pathophysiology, whether Nox enzymes contribute to obesity-mediated bone remodeling remains to be clearly elucidated. Nox2 is one of the ... -
The power of phytochemicals combination in cancer chemoprevention
Rizeq, Balsam; Gupta, Ishita; Ilesanmi, Josephine; AlSafran, Mohammed; Rahman, MD Mizanur; Ouhtit, Allal... more authors ... less authors ( Ivyspring International Publisher , 2020 , Article Review)Conventional therapies for cancer treatment have posed many challenges, including toxicity, multidrug resistance and economic expenses. In contrast, complementary alternative medicine (CAM), employing phytochemicals have ...