Browsing Laboratory Animal Research Center by Author "Muralitharan, Shanmugakonar"

Now showing items 1-4 of 4

    • CARMA2sh and ULK2 control pathogen-associated molecular patterns recognition in human keratinocytes: psoriasis-linked CARMA2sh mutants escape ULK2 censorship 

      Scudiero, Ivan; Mazzone, Pellegrino; D'Andrea, Luca E.; Ferravante, Angela; Zotti, Tiziana; ... more authors ( Nature , 2017 , Article)
      The molecular complexes formed by specific members of the family of CARMA proteins, the CARD domain-containing adapter molecule BCL10 and MALT1 (CBM complex) represent a central hub in regulating activation of the pleiotropic ...

    • Claudin-1, A Double-Edged Sword in Cancer. 

      Bhat, Ajaz A; Syed, Najeeb; Therachiyil, Lubna; Nisar, Sabah; Hashem, Sheema; ... more authors ( MDPI , 2020 , Article Review)
      Claudins, a group of membrane proteins involved in the formation of tight junctions, are mainly found in endothelial or epithelial cells. These proteins have attracted much attention in recent years and have been implicated ...

    • Effect of psoriasis linked CARMA2sh gene in transgenic animal model 

      Kavitha, Varadharajan; Muralitharan, Shanmugakonar; Vito, Pasquale (2018 , Poster)
      Background • CARMA2 belongs to the CARMA family of proteins. They are involved in the regulation and activation of NF-κB, that has a central role in controlling the immune and inflammatory response, cell survival and ...

    • Quality of Drinking water in Qatar University Rodent vivarium 

      Khan, Imran; Muralitharan, Shanmugakonar; Al-Naemi, Hamda (2018 , Poster)
      Edstrom watering system was newly installed and all the accessories were used for limited run, but gradually the system runs continuously and this improved the water quality . Moreover our microbial count of water samples ...