تصفح Laboratory Animal Research Center حسب المؤلف "Abdul Q., Khan"
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F-box proteins in cancer stemness: An emerging prognostic and therapeutic target
Abdul Q., Khan; Al-Tamimi, Maha; Uddin, Shahab; Steinhoff, Martin ( Elsevier , 2021 , Article)Cancer is a complex heterogenic disease with significant therapeutic challenges. The presence of cancer stem cells (CSCs) in cancer tissue orchestrates tumor growth, progression, and metastasis, the tumor heterogeneity, ... -
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids
Abdul Q., Khan; Rashid, Khalid; AlAmodi, Abdulhadi A.; Agha, Maha Victor; Akhtar, Sabah; Hakeem, Ishrat; Raza, Syed Shadab; Uddin, Shahab... more authors ... less authors ( Elsevier , 2021 , Article)Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of human diseases including cancer. In this line, now it has become evident that ROS level/concentration is a major factor in the growth, ... -
Role of animal research in human malignancies
Abdul Q., Khan; Siveen, Kodappully S.; Prabhu, Kirti S.; Kuttikrishnan, Shilpa; Akhtar, Sabah; Shanmugakonar, Muralitharan; Al-Naemi, Hamda A.; Haris, Mohammad; Uddin, Shahab... more authors ... less authors ( Elsevier , 2019 , Book chapter)Animal models are the central backbone in relation to providing the safety information of xenobiotics, the nature of chemicals present in the environment, and understanding the developmental process in disease pathogenesis ...