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Comparison of potential inhibitors and targeting fat mass and obesity-associated protein causing diabesity through docking and molecular dynamics strategies.
(
Wiley
, 2021 , Article)
Genome-wide association studies (GWAS) have identified an association between polymorphisms in the FTO gene and obesity. The FTO: rs9939609, an intronic variant, is considered a risk allele for developing diabesity in ...
miR-21 mimic blocks obesity in mice: A novel therapeutic option
(
Elsevier
, 2021 , Article)
MicroRNAs (miRNAs) are promising drug targets for obesity and metabolic disorders. Recently, miRNA mimics are providing a unique mechanism of action that guides the process for drug development and sets out the context of ...
Identification of Adolescents with Adiposities and Elevated Blood Pressure and Implementation of Preventive Measures Warrants the Use of Multiple Clinical Assessment Tools
(
MDPI
, 2021 , Article)
Background: The burden of abdominal adiposity has increased globally, which is recognized as a key condition for the development of obesity-related disorders among youth, including type 2 diabetes, cardiovascular disease, ...
Sulforaphane reduces obesity by reversing leptin resistance.
(
eLife Sciences Publications
, 2022 , Article)
The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress ...
The impact of health status, diet and lifestyle on non-alcoholic fatty liver disease: Narrative review
(
Wiley
, 2022 , Article Review)
Non-alcoholic fatty liver disease (NAFLD) is defined as the abnormal accumulation of triglycerides in the liver. NAFLD has a global prevalence of almost 30%, while incidence is rising with increasing levels of obesity, ...
Consequences of a Great Crisis on Chronic Diseases: How Childhood Exposures May Shape Future Health
(
John Wiley and Sons Inc
, 2021 , Article)
[No abstract available]
Health consequences of obesity and projected future obesity health burden in China
(
Wiley
, 2022 , Article Review)
Objective: This study examined the effects of overweight/obesity on mortality and morbidity outcomes and the disparities, time trends, and projected future obesity health burden in China. Methods: Cohort studies that ...
Association Between Nutrition Literacy and Overweight/Obesity of Adolescents: A Cross–Sectional Study in Chongqing, China
(
Frontiers Media
, 2022 , Article)
Objective: The burden of overweight and obesity in adolescents is increasing rapidly. This study aimed to assess the association between nutrition literacy and overweight/obesity among adolescents in China. Methods: This ...
Prevalence, Management, and Associated Factors of Obesity, Hypertension, and Diabetes in Tibetan Population Compared with China Overall
(
MDPI
, 2022 , Article Review)
Tibetans’ life expectancy lags behind China’s average. Obesity and noncommunicable diseases (NCDs) contribute to health disparity, but NCD patterns among Tibetans are unknown. To examine the prevalence, management, and ...
Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
(
MDPI
, 2022 , Article)
Background: Hypoxia is caused by the excessive expansion of the white adipose tissue (AT) and is associated with obesity-related conditions such as insulin resistance, inflammation, and oxidative stress. Docosahexaenoic ...