Browsing by Author "Rizk, Nasser M."
Now showing items 1-17 of 17
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The Association between Serum LDL Cholesterol and Genetic Variation in Chromosomal Locus 1p13.3 among Coronary Artery Disease Patients
Rizk, Nasser M.; El-Menyar, Ayman; Egue, Huda; Wais, Idil Souleman; Baluli, Hissa Mohamed; Alali, Khalid; Farag, Fathi; Younes, Noura; Al Suwaidi, Jassim... more authors ... less authors ( Hindawi , 2015 , Article)Background. Several polymorphisms of a locus on chromosome 1p13.3 have a significant effect on low-density lipoprotein cholesterol (LDL-C), atherosclerosis, and acute coronary syndrome (ACS). Methods. We aimed to investigate ... -
Association of lipid profile and waist circumference as cardiovascular risk factors for overweight and obesity among school children in Qatar
Rizk, Nasser M.; Yousef, Mervat ( Dove Medical Press , 2012 , Article)Background: Childhood obesity is a national as well as worldwide problem. The aim of this study was to evaluate the association of overweight and obesity among Qatari children with lipid profile and waist circumference as ... -
Association of β-Adrenergic Receptor Gene Polymorphisms With Acute Coronary Syndrome and Cardiovascular Risk Factors in an Arab Population
El-Menyar, Ayman; Rizk, Nasser M.; Asim, Mohammad; Al-Thani, Hassan; Elgendy, Akram; Al-Suwaidi, Jassim... more authors ... less authors ( SAGE Publications Inc. , 2016 , Article)We evaluated the association between beta-adrenergic receptor genes (ADRB1 and ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in individuals from an Arab ethnicity. A total of 388 Qatari ... -
Associations of Vitamin D Receptor Polymorphism rs1544410 with Adiposity Phenotypes
Sharif, Elham; Swaidan, Nuha; Shurbaji, Samar; Rizk, Nasser M. ( MedCrave , 2016 , Article)Background: Vitamin D receptor (VDR) is present on adipocytes, and many studies were performed to investigate the association between polymorphisms in VDR gene with obesity. However, in the Arab Gulf populations, whereas ... -
The cardiovascular implication of single nucleotide polymorphisms of chromosome 9p21 locus among Arab population
El-Menyar, Ayman A.; Rizk, Nasser M.; Al-Qahtani, Awad; AlKindi, Fahad; Elyas, Ahmed; Farag, Fathi; Bakhsh, Fadheela Dad; Ebrahim, Samah; Ahmed, Emad; Al-khinji, Mooza; Al-Thani, Hassan; Al Suwaidi, Jassim... more authors ... less authors ( Medknow Publications , 2015 , Article)Background: Based on several reports including genome-wide association studies, genetic variability has been linked with higher (nearly half) susceptibility toward coronary artery disease (CAD). We aimed to evaluate the ... -
Docosahexaenoic Acid Counteracts the Hypoxic-Induced Inflammatory and Metabolic Alterations in 3T3-L1 Adipocytes
Younes, Noura B.; Mohamed, Omnia Ahmed; Rizk, Nasser M. ( MDPI , 2022 , Article)Background: Hypoxia is caused by the excessive expansion of the white adipose tissue (AT) and is associated with obesity-related conditions such as insulin resistance, inflammation, and oxidative stress. Docosahexaenoic ... -
Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
Rizk, Nasser M; Saleh, Amena; Elsayegh, Dina; Algamal, Abdelrahman ( FASEB , 2020 , Conference Paper)Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ... -
The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Rizk, Nasser M; ElGamal, Abdelrahman; Elsayegh, Dina; Cakir, Isin; Ghamari-Langroudi, Masoud ( Endocrine Society , 2020 , Conference Paper)The Expression of TBC1 Domain Family, member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane. Background: Obesity is commonly accompanied by impaired glucose homeostasis. Decreased ... -
The Immunophenotyping Changes of Peripheral CD4+ T Lymphocytes and Inflammatory Markers of Class III Obesity Subjects After Laparoscopic Gastric Sleeve Surgery - A Follow-Up Study
Rizk, Nasser M; Fadel, Amina; AlShammari, Wasaif; Younes, Noura; Bashah, Moataz ( Dovepress , 2021 , Article)Obesity is a chronic disorder characterized by a low-grade inflammatory state and immune cell irregularities. The study aimed to follow up on the changes in the peripheral CD4+ T lymphocytes and the pro-inflammatory ... -
Integrated datasets of proteomic and metabolomic biomarkers to predict its impacts on comorbidities of type 2 diabetes mellitus
Cheema, Amrita K.; Kaur, Prabhjit; Fadel, Amina; Younes, Noura; Zirie, Mahmoud; Rizk, Nasser M.... more authors ... less authors ( Dove Medical Press , 2020 , Article)© 2020 Cheema et al. Objective: The objective of the current study is to accomplish a relative exploration of the biological roles of differentially dysregulated genes (DRGs) in type 2 diabetes mellitus (T2DM). The study ... -
iTRAQ-based quantitative protein expression profiling and MRM verification of markers in type 2 diabetes.
Uppal, , Arushi; Dennis, Kevin; Karve, ,Tejaswita; Blakeslee, , Kenneth; Kwagyan, John; Zirie, , Mahmoud; Younes, Noura; Ibrahim, Sereen; Kaur, , Prabhjit; Rizk, Nasser M; Cheema, Amrita K... more authors ... less authors ( American Chemical Society , 2012 , Article)The pathogenesis of Type 2 diabetes mellitus (T2DM) is complex owing to molecular heterogeneity in the afflicted population. Current diagnostic methods rely on blood glucose measurements, which are noninformative with ... -
Leptin And Free Leptin Receptor Is Associated With Polycystic Ovary Syndrome In Young Women
Sharif, Elham; Rizk, Nasser M. ( Hindawi Publishing Corporation , 2015 , Article)Leptin has two forms in the circulation: free and bound forms. The soluble leptin receptor (sOB-R) circulates in the blood and can bind to leptin. The aim of this study is to assess the concentrations of the leptin and ... -
Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I
Alwakeel, Mariam; Galash, Afnan O.; Saleh, Amina; Alkhanji, FadelMooza; Rizk, Nasser M. ( Hamad bin Khalifa University Press (HBKU Press) , 2018 , Conference Paper)Title: Obesity is associated with the upregulation of TLR4 protein but not associated with polymorphisms of TLR4D299G TLR4T399I.Background: Toll-like-receptor 4 (TLR4) is a pathogen-specific receptor, expressed in white ... -
Prevalence and Predictors of Insulin Resistance in Non-Obese Healthy Young Females in Qatar
Elrayess, Mohamed A.; Rizk, Nasser M.; Fadel, Amina S.; Kerkadi, Abdelhamid ( MDPI , 2020 , Article)The state of Qatar suffers from diabetes epidemic due to obesity-associated metabolic syndrome. However, the prevalence of insulin resistance prior to obesity, which could play an important role in the high prevalence of ... -
Risk Management Assessments and Recommendations Among Students, Staffs, and Health Care Workers in Educational Biomedical Laboratories.
Rizk, Nasser M; AlShammari, Wasaif; Alhussain, Hashim (2021 , Article)Safety in laboratories is one of the most crucial topics for all educational institutes. All-hazards need to be identified, evaluated, and controlled whenever possible, following the risk management (RM) process. This study ... -
Sulforaphane reduces obesity by reversing leptin resistance.
Çakır, Işın; Lining Pan, Pauline; Hadley, Colleen K; El-Gamal, Abdulrahman; Fadel, Amina; Elsayegh, Dina; Mohamed, Omnia; Rizk, Nasser M; Ghamari-Langroudi, Masoud... more authors ... less authors ( eLife Sciences Publications , 2022 , Article)The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress ... -
TLR4 Receptor D299G/T399I Haplotype Polymorphism Is Associated with Insulin Resistance in Obese Female Subjects
Sharif, Elham; Al-Wakeel, Mariam; Mohamed, Afnan; kerkadi, Abdelhamid; Rizk, Nasser M (2020 , Article)Background: Activation of Toll-like-receptor 4 (TLR4) causes chronic inflammation that can result in obesity and metabolic syndrome (MeS). Aim: This study aimed to investigate the role of TLR4 polymorphisms of TLR4D299G/T399I, ...