Browsing by Author "Maaliki, Dina"
Now showing items 1-5 of 5
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Estrogen increases expression of vascular alpha 2C adrenoceptor through the cAMP/Epac/JNK/AP-1 pathway and potentiates cold-induced vasoconstriction
Fardoun, Manal M.; Issa, Khodr; Maaliki, Dina; Nasser, Suzanne A.; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Elsevier , 2020 , Article)Cutaneous cold-induced vasoconstriction is a normal physiological reaction mediated by alpha 2C-adrenergic receptors (α2C-ARs) expressed in vascular smooth muscle cells (VSMCs). When this reaction is exaggerated, Raynaud's ... -
Flavonoids in adipose tissue inflammation and atherosclerosis: One arrow, two targets
Fardoun, Manal Muin; Maaliki, Dina; Halabi, Nabil; Iratni, Rabah; Bitto, Alessandra; Baydoun, Elias; Eid, Ali H.... more authors ... less authors ( Portland Press Ltd , 2020 , Article Review)Flavonoids are polyphenolic compounds naturally occurring in fruits and vegetables, in addition to beverages such as tea and coffee. Flavonoids are emerging as potent therapeutic agents for cardiovascular as well as metabolic ... -
Flavonoids in hypertension: a brief review of the underlying mechanisms.
Maaliki, Dina; Shaito, Abdullah A; Pintus, Gianfranco; El-Yazbi, Ahmed; Eid, Ali H ( Elsevier , 2019 , Article)Flavonoids are a diverse group of bioactive polyphenolic compounds abundant in dietary plants and herbs. Regular consumption of flavonoids exerts cardio-vasculoprotective effects and may reduce the onset or progression of ... -
The role of α2-adrenergic receptors in hypertensive preeclampsia: A hypothesis
Maaliki, Dina; Issa, Khodr; Al Shehabi, Tuqa; El-Yazbi, Ahmed; Eid, Ali H. ( Wiley Blackwell , 2019 , Article Review)Preeclampsia, a major disorder of human pregnancy, manifests as persistent hypertension and proteinuria presenting after 20 weeks of pregnancy. Multiple systemic symptoms might be associated with preeclampsia including ... -
Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
Fardoun, Manal; Al-Shehabi, Tuqa; El-Yazbi, Ahmed; Issa, Khodr; Zouein, Fouad; Maaliki, Dina; Iratni, Rabah; Eid, Ali H.... more authors ... less authors ( Hindawi Limited , 2017 , Article)Cardiovascular disease (CVD) continues to be the leading cause of death worldwide. Atherosclerosis is a CVD characterized by plaque formation resulting from inflammation-induced insults to endothelial cells, monocytes, and ...