Browsing by Author "Rayan, Menatallah"
Now showing items 1-9 of 9
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Chemically modified mRNA beyond COVID-19: Potential preventive and therapeutic applications for targeting chronic diseases
( Elsevier , 2022 , Article Review)Chemically modified mRNA represents a unique, efficient, and straightforward approach to produce a class of biopharmaceutical agents. It has been already approved as a vaccination-based method for targeting SARS-CoV-2 ... -
Crosstalk between Sodium–Glucose Cotransporter Inhibitors and Sodium–Hydrogen Exchanger 1 and 3 in Cardiometabolic Diseases
( MDPI , 2021 , Article)Abnormality in glucose homeostasis due to hyperglycemia or insulin resistance is the hallmark of type 2 diabetes mellitus (T2DM). These metabolic abnormalities in T2DM lead to cellular dysfunction and the development of ... -
Empagliflozin inhibits angiotensin II-induced hypertrophy in H9c2 cardiomyoblasts through inhibition of NHE1 expression
( Springer , 2022 , Article)Diabetes mellitus (DM)-induced cardiac morbidities have been the leading cause of death among diabetic patients. Recently, sodium-glucose cotransporter-2 (SGLT-2) inhibitors including empagliflozin (EMPA), which have been ... -
Ethanol-Based Proliposomes Incorporating Dexamethasone for The Treatment of COVID-19 Acute Respiratory Distress Syndrome (ARDS) Using Medical Nebulizers
(2023 , Master Thesis)Background/Objective: Systemic dexamethasone has demonstrated mortality reduction in COVID-19-related acute respiratory distress syndrome (ARDS). The aim of this study is to use ethanol-based proliposome technology to ... -
Evaluating the effects of sodium glucose co-transporter -2 inhibitors from a renin–angiotensin–aldosterone system perspective in patients infected with COVID-19: contextualizing findings from the dapagliflozin in respiratory failure in patients with COVID-19 study
( Springer , 2022 , Article Review)Numerous studies demonstrate parallels between CVD, type 2 diabetes mellitus (T2DM) and COVID-19 pathology, which accentuate pre-existing complications in patients infected with COVID-19 and potentially exacerbate the infection ... -
Exploring the link between environmental chemical exposures and epigenetic modifications in diabetes mellitus.
( The Association of Basic Medical Sciences , 2025 , Article Review)Diabetes mellitus (DM) is a globally prevalent metabolic disorder characterized by impaired glucose homeostasis and insulin secretion. Beyond traditional risk factors like lifestyle and genetics, environmental pollutants, ... -
The role of immune checkpoints in modulating cancer stem cells anti-tumor immune responses: implications and perspectives in cancer therapy
( BioMed Central Ltd , 2025 , Article Review)Cancer stem cells (CSCs) are a minor subpopulation of tumor cells characterized by self-renewal capacity and stemness features and are responsible for tumor progression and therapy resistance. Several studies have shown ... -
Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development
( BioMed Central Ltd , 2024 , Article Review)Gut microbiota regulates various aspects of human physiology by producing metabolites, metabolizing enzymes, and toxins. Many studies have linked microbiota with human health and altered microbiome configurations with the ... -
Unlocking the secrets: exploring the influence of the aryl hydrocarbon receptor and microbiome on cancer development.
( Springer Nature , 2024 , Article)Gut microbiota regulates various aspects of human physiology by producing metabolites, metabolizing enzymes, and toxins. Many studies have linked microbiota with human health and altered microbiome configurations with the ...
