تصفح حسب المؤلف "Qoronfleh, M. Walid"

السجلات المعروضة 1 -- 10 من 10

    • Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar 

      Ismail, Mohamed A; Samara, Muthanna; Al Sayab, Ali; Alsharshani, Mohamed; Yassin, Mohamed A; ... more authors ( Wiley Open Access , 2020 , Article)
      Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ...

    • Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar 

      Al-Sharshani, Dalal; Velayutham, Dinesh; Samara, Muthanna; Gazal, Reham; Al Haj Zen, Ayman; ... more authors ( Wiley-Blackwell , 2023 , Article)
      Background: Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). Objective: The study aimed to investigate ...

    • Autism and the Scaffolding Protein Neurobeachin 

      Mohammed, Sawsan; Qoronfleh, M. Walid ( Springer , 2022 , Book chapter)
      Autism is a group of early onsets, diverse, lifelong, neurodevelopmental conditions that affect social interaction, verbal and non-verbal communications as well as behavior. It is a multifactorial condition, which results ...

    • Current Technologies and Future Perspectives in Immunotherapy towards a Clinical Oncology Approach 

      Adhikary, Subhamay; Pathak, Surajit; Palani, Vignesh; Acar, Ahmet; Banerjee, Antara; ... more authors ( MDPI , 2024 , Article Review)
      Immunotherapy is now established as a potent therapeutic paradigm engendering antitumor immune response against a wide range of malignancies and other diseases by modulating the immune system either through the stimulation ...

    • Genomic Newborn Screening for Pediatric Cancer Predisposition Syndromes: A Holistic Approach 

      Linga, Bala Subramani Gattu; Mohammed, Sawsan G.A.A.; Farrell, Thomas; Rifai, Hilal Al; Al-Dewik, Nader; ... more authors ( MDPI , 2024 , Article Review)
      As next-generation sequencing (NGS) has become more widely used, germline and rare genetic variations responsible for inherited illnesses, including cancer predisposition syndromes (CPSs) that account for up to 10% of ...

    • Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies. 

      Younes, Salma; Ismail, Mohamed A; Al-Jurf, Rana; Ziyada, Ayah; Nasrallah, Gheyath K; ... more authors ( taylor and francis online , 2023 , Article)
      Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ...

    • Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy 

      Basar, Oyku Yagmur; Mohammed, Sawsan; Qoronfleh, M. Walid; Acar, Ahmet ( Frontiers Media , 2024 , Article Review)
      Metronomic chemotherapy (MCT), characterized by the continuous administration of chemotherapeutics at a lower dose without prolonged drug-free periods, has garnered significant attention over the last 2 decades. Extensive ...

    • Optimizing Clinical Workflow Using Precision Medicine and Advanced Data Analytics 

      Zhai, Kevin; Yousef, Mohammad S.; Mohammed, Sawsan; Al-Dewik, Nader I.; Qoronfleh, M. Walid ( MDPI , 2023 , Article)
      Precision medicine—of which precision prescribing is a core component—is becoming a new frontier in today’s healthcare. Both artificial intelligence (AI) and machine learning (ML) have the potential to enhance our understanding ...

    • A Perspective on Patient Safety Culture among Nurses in Qatar 

      Qoronfleh, M. Walid; Essa, Musthafa Mohamed; Mohammed, Sawsan ( Wolters Kluwer , 2023 , Other)
      Background: The vitality of developing a safety culture in healthcare settings has become increasingly important following international investigations that highlighted the failures in health care delivery. Nurses, being ...

    • Prevalence, predictors, and outcomes of major congenital anomalies: A population-based register study 

      Al-Dewik, Nader; Samara, Muthanna; Younes, Salma; Al-jurf, Rana; Nasrallah, Gheyath; ... more authors ( Nature Research , 2023 , Article)
      Congenital anomalies (CAs) are a leading cause of morbidity and mortality in early life. We aimed to assess the incidence, risk factors, and outcomes of major CAs in the State of Qatar. A population-based retrospective ...