• A novel human pain insensitivity disorder caused by a point mutation in ZFHX2 

      Habib A.M.; Matsuyama A.; Okorokov A.L.; Santana-Varela S.; Bras J.T.; ... more authors ( Oxford University Press , 2018 , Article)
      Chronic pain is a major global public health issue causing a severe impact on both the quality of life for sufferers and the wider economy. Despite the significant clinical burden, little progress has been made in terms ...
    • Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity 

      Habib A.M.; Okorokov A.L.; Hill M.N.; Bras J.T.; Lee M.-C.; ... more authors ( Elsevier Ltd , 2019 , Article)
      The study of rare families with inherited pain insensitivity can identify new human-validated analgesic drug targets. Here, a 66-yr-old female presented with nil requirement for postoperative analgesia after a normally ...