Browsing by Author "Chen, Weiwei"

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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch

Zhang, Wenhao; Dai, Xiaolong; Chen, Weiwei; Li, Yanqing; Mei, Huiyuan; Buddenkotte, Jorg; Zhu, Xingyun; Steinhoff, Martin; Wang, Jiafu; Meng, Jianghui... more authors ... less authors ( Elsevier , 2025 , Article)
BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, ...
Neuronal BST2: A Pruritic Mediator alongside Protease-Activated Receptor 2 in the IL-27–Driven Itch Pathway

Yanqing, Li; Chen, Weiwei; Zhu, Xingyun; Mei, Huiyuan; Steinhoff, Martin; Buddenkotte, Joerg; Wang, Jinhai; Zhang, Wenhao; Li, Zhenghui; Dai, Xiaolong; Shan, Chunxu; Wang, Jiafu; Meng, Jianghui... more authors ... less authors ( Elsevier , 2024 , Article)
Chronic itch is a common and complex symptom often associated with skin diseases such as atopic dermatitis (AD). Although IL-27 is linked to AD, its role and clinical significance in itch remain undefined. We sought to ...