Browsing by Author "Zaraket, Hassan"
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Antigenica and Genetic Characterization of Identified Rotavirus Strains in Qatar In Response to Rotarix Vaccine Usage
( Qatar University Press , 2020 , Poster)Aim: To identify genetic and antigenic variation in RV in response to vaccine usage. Methods: A total of 231 RV-positive fecal samples were collected from children suffering from AGE during three-year study period between ... -
Epidemiological, Molecular, and Clinical Features of Norovirus Infections among Pediatric Patients in Qatar
( MDPI , 2019 , Article)Abstract: Background: Norovirus (NoV) is recognized as the second most important etiological agent leading to acute gastroenteritis globally. In order to determine the burden and characteristics of NoV infections in children ... -
Epidemiological, molecular, and clinical features of rotavirus infections among pediatrics in Qatar
( Springer , 2021 , Article)Acute gastroenteritis (AGE) remains a major cause of diarrhea in developing and developed countries. Rotavirus (RV) is a leading cause of severe pediatric diarrhea worldwide. Here we report on the prevalence of circulating ... -
Macrophage responses associated with COVID-19: A pharmacological perspective
( Elsevier , 2020 , Article)COVID-19 has caused worldwide death and economic destruction. The pandemic is the result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has demonstrated high rates of infectivity leading to great ... -
Molecular Insights Into SARS COV-2 Interaction With Cardiovascular Disease: Role of RAAS and MAPK Signaling
( Frontiers Media S.A. , 2020 , Article)In December 2019, reports of viral pneumonia came out of Wuhan city in Hubei province in China. In early 2020, the causative agent was identified as a novel coronavirus (CoV) sharing some sequence similarity with SARS-CoV ... -
Platforms Exploited for SARS-CoV-2 Vaccine Development.
( MDPI , 2020 , Article Review)The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the only zoonotic-origin coronavirus (CoV) that has reached the pandemic stage. The virus uses its spike (S) glycoprotein to attach to the host cells ... -
Repurposing Ivermectin for COVID-19: Molecular Aspects and Therapeutic Possibilities
( Frontiers Media , 2021 , Article)As of January 2021, SARS-CoV-2 has killed over 2 million individuals across the world. As such, there is an urgent need for vaccines and therapeutics to reduce the burden of COVID-19. Several vaccines, including mRNA, ... -
Seasonality of Respiratory Viral Infections: Will COVID-19 Follow Suit?
( Frontiers Media , 2020 , Article Review)Respiratory viruses, including coronaviruses, are known to have a high incidence of infection during winter, especially in temperate regions. Dry and cold conditions during winter are the major drivers for increased ... -
Vaccine evaluation and genotype characterization in children infected with rotavirus in Qatar
( Springer Nature , 2023 , Article)Background: We characterized and identified the genetic and antigenic variations of circulating rotavirus strains in comparison to used rotavirus vaccines. Methods: Rotavirus-positive samples (n = 231) were collected and ... -
Viral metagenomics analysis of stool specimens from children with unresolved gastroenteritis in Qatar
( Elsevier , 2022 , Article)Acute gastroenteritis (AGE) is associated with significant global morbidity and mortality, especially among children under five years of age. Viruses are well established as etiologic agents of gastroenteritis since they ...
