Browsing by Author "Lai, F."

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Advancing male age differentially alters levels and localization patterns of PLCzeta in sperm and testes from different mouse strains

Kashir, Junaid; Mistry, Bhavesh; Gumssani, Maha; Rajab, Muhammad; Abu-Dawas, Reema; Almohanna, Falah; Nomikos, Michail; Jones, Celine; Abu-Dawud, Raed; Al-Yacoub, Nadya; Coward, Kevin; Lai, F.; Assiri, Abdullah... more authors ... less authors ( Medknow Publications , 2021 , Article)
Sperm-specific phospholipase C zeta (PLC) initiates intracellular calcium (Ca2+) transients which drive a series of concurrent events collectively termed oocyte activation. Numerous investigations have linked abrogation ...
Hypertrophic cardiomyopathy-linked variants of cardiac myosin-binding protein C3 display altered molecular properties and actin interaction

Da'as, Sahar I.; Fakhro, Khalid; Thanassoulas, Angelos; Krishnamoorthy, Navaneethakrishnan; Saleh, Alaaeldin; Calver, Brian L.; Safieh-Garabedian, Bared; Toft, Egon; Nounesis, George; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( Portland Press Ltd , 2018 , Article)
The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in cardiac myosin-binding protein C3 (c-MYBPC3) gene, is the leading ...