Browsing by Author "Doi, Suhail A."
Now showing items 1-20 of 35
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Assessing the consistency of iPSC and animal models in cystic fibrosis modelling: A metaanalysis
( Public Library of Science , 2022 , Article)Introduction Cystic fibrosis (CF) is a hereditary autosomal recessive disorder caused by a range of mutations in the CF Transmembrane Conductance Regulator (CFTR) gene. This gene encodes the CFTR protein, which acts as a ... -
Comparative effectiveness of malaria prevention measures: a systematic review and network meta-analysis.
( BMC , 2018 , Article Review)Malaria causes significant morbidity and mortality worldwide. There are several preventive measures that are currently employed, including insecticide-treated nets (ITNs, including long-lasting insecticidal nets and ... -
Comparison of bias adjustment methods in meta-analysis suggests that quality effects modeling may have less limitations than other approaches.
( Elsevier , 2019 , Article)The quality of primary research is commonly assessed before inclusion in meta-analyses. Findings are discussed in the context of the quality appraisal by categorizing studies according to risk of bias. The impact of appraised ... -
Differential impact of mass and targeted praziquantel delivery on schistosomiasis control in school-aged children: A systematic review and meta-analysis.
( Public Library of Science , 2019 , Article)Schistosomiasis is a widespread public health concern in the poorest regions of the world. The principal control strategy is regular praziquantel administration to school-aged children in endemic areas. With calls for the ... -
The Economic Impact of Optimizing a COVID-19 Management Protocol in Pre-Existing Cardiovascular Disease Patients
( Elsevier , 2022 , Article)This study answers the question of whether the health care costs of managing COVID-19 in preexisting cardiovascular diseases (CVD) patients increased or decreased as a consequence of evidence-based efforts to optimize the ... -
Effectiveness of Different Topical Treatments in the Healing of Pressure Injuries: A Network Meta-analysis.
( Elsevier , 2018 , Article)Pressure injuries (PIs) are one of the most common types of complex wounds and impose a huge economic burden on the healthcare system and the patients. A plethora of topical treatments is widely available for PI treatment, ... -
Efficacy of a 3-day pre-travel schedule of Tafenoquine for malaria chemoprophylaxis: A network meta-analysis.
( Oxford University Press , 2021 , Article)Chemoprophylaxis with weekly doses of tafenoquine (200 mg/day for 3 days before departure [loading dose], 200 mg/week during travel and one-week post-travel [maintenance doses]) is effective in preventing malaria. Effectiveness ... -
Efficacy of Anthelminthic Drugs and Drug Combinations Against Soil-transmitted Helminths: A Systematic Review and Network Meta-analysis.
( Oxford University Press , 2019 , Article)Periodic mass distribution of benzimidazole anthelminthic drugs is the key strategy to control soil-transmitted helminths (STHs) globally. However, benzimidazoles have low efficacy against Trichuris trichiura, and there ... -
Efficacy of chloroquine and hydroxychloroquine in treating COVID-19 infection: A meta-review of systematic reviews and an updated meta-analysis
( Elsevier , 2021 , Article)To synthesize findings from systematic reviews and meta-analyses on the efficacy and safety of chloroquine (CQ) and hydroxychloroquine (HCQ) with or without Azithromycin for treating COVID-19, and to update the evidence ... -
A generalized pairwise modelling framework for network meta-analysis.
( Lippincott, Williams & Wilkins , 2018 , Article)Indirect comparison methods are used to measure the effect of two treatments that were each compared against a similar control group in a meta-analysis. The network meta-analysis method extends this to multiple treatments ... -
Hormonal predictors of the insulin sensitive phenotype in humans.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and a heightened risk of comorbidities. This study aimed to identify hormonal predictors of an insulin-sensitive ... -
Hormonal predictors of the lean phenotype in humans.
( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity is characterized by excessive fat accumulation and an increased risk of numerous associated comorbidities. Adipose tissue secretes leptin and other adipokines, which play key roles in regulating energy ... -
Immunogenicity after pre- and post-exposure rabies vaccination: A systematic review and dose-response meta-analysis
( Elsevier , 2021 , Article)There are a myriad of vaccine schedules for rabies pre- (PrEP) and post-exposure prophylaxis (PEP) that differ in the number and timedoses, number of visits, length of schedule, and route of administration. The objective ... -
The impact of prior obesity surgery on glucose metabolism after body contouring surgery: A pilot study.
( Europe PMC , 2023 , Article)Body contouring surgery enhances physical appearance by means of surgical subcutaneous fat removal (SSFR). However, it remains unclear how SSFR may affect glucose metabolism and its broader effects on the endocrine system, ... -
Investigating the impact of trial retractions on the healthcare evidence ecosystem (VITALITY Study I): retrospective cohort study.
( BMJ Publishing Group Ltd , 2025 , Article)To investigate the impact of retracted trials on the production and use of healthcare evidence in the evidence ecosystem. Retrospective cohort study based on forward citation searching. Retraction Watch up to 5 November ... -
Letter re: stratification by quality is not recommended in meta-analysis.
( Elsevier , 2019 , Article)We read with interest the letter by Page et al. [1] who disagree with the conclusions of our paper, “Stratification by quality induced selection bias in a meta-analysis of clinical trials” [2]. Page et al. [1] critique the ... -
Meta-analysis in evidence-based healthcare: a paradigm shift away from random effects is overdue.
( University of Adelaide, Joanna Briggs Institute , 2017 , Article)Each year up to 20 000 systematic reviews and meta-analyses are published whose results influence healthcare decisions, thus making the robustness and reliability of meta-analytic methods one of the world's top clinical ... -
Metabolic changes after surgical fat removal: A dose–response meta-analysis
( Elsevier , 2023 , Article Review)BackgroundBariatric surgery averts obesity-induced insulin resistance and the metabolic syndrome. By contrast, surgical fat removal is considered merely an esthetic endeavor. The aim of this article was to establish whether ... -
Metformin in pregnancy to avert gestational diabetes in women at high risk: Meta-analysis of randomized controlled trials.
( Wiley , 2019 , Article Review)Previous randomized and observational studies on the efficacy of metformin in pregnancy to reduce incident gestational diabetes mellitus (GDM) in women at high risk (obesity, polycystic ovary syndrome [PCOS], or pregestational ... -
Moving towards a standards-based methodological quality assessment scheme for clinical research
( Lippincott, Williams & Wilkins , 2019 , Article)None
