Browsing by Author "Anwardeen, Najeha"
Now showing items 1-20 of 21
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Antioxidative Stress Metabolic Pathways in Moderately Active Individuals
( MDPI , 2023 , Article)Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood. ... -
Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
( Lippincott, Williams & Wilkins , 2024 , Article)Oxidative stress plays a pivotal role in the development of metabolic syndrome, including heart failure and insulin resistance. The N-terminal fragment of brain natriuretic peptide (NT-proBNP) has been associated with ... -
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells.
( Bentham Science Publishers , 2024 , Article)Cell culture plays a crucial role in addressing fundamental research questions, particularly in studying insulin resistance (IR) mechanisms. Multiple in vitro models are utilized for this purpose, but their technical ... -
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
( MDPI , 2022 , Article)(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy ... -
Comparing the metabolic signatures of obesity defined by waist circumference, waist-hip ratio, or BMI
( John Wiley and Sons Inc , 2024 , Article)Objective: Measuring obesity is crucial for assessing health risks and developing effective prevention and treatment strategies. The most common methods used to measure obesity include BMI, waist circumference, and waist-hip ... -
Correction to: Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels (Emergent Materials, (2025), 8, 2, (985-998), 10.1007/s42247-024-00888-7)
( Springer Nature , 2025 , Article)The original version of this publication contained wrong texts in the Acknowledgement section and in the Author contributions section. In addition, the article note on page 1 has been corrected. These errors have been ... -
Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women
( Nature Research , 2025 , Article)Regular aerobic exercise has a significant impact on glucose metabolism and lipid profiles, contributing to overall health improvement. However, evidence for optimal exercise duration to achieve these effects is limited. ... -
Indoleacetylglutamine Pathway Is a Potential Biomarker for Cardiovascular Diseases
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality. Metabolomics allows for the identification of important biomarkers for CVDs, essential for early detection and risk assessment. This ... -
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
( Springer , 2025 , Article)Nanoparticles (NP) have gained significant attention in biomedical research due to their unique properties and potential applications in drug delivery, imaging, and diagnostics. Gold (AuNPs) and silver (AgNPs) NPs are among ... -
Joint Effects of Exercise and Ramadan Fasting on Telomere Length: Implications for Cellular Aging
( MDPI , 2024 , Article)Aging is a fundamental biological process that progressively impairs the functionality of the bodily systems, leading to an increased risk of diseases. Telomere length is one of the most often used biomarkers of aging. ... -
Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings
( Frontiers Media SA , 2024 , Article)Introduction: Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. ... -
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity.
( Frontiers Media , 2022 , Article)Increased COVID-19 disease severity is higher among patients with type 2 diabetes mellitus and hypertension. However, the metabolic pathways underlying this association are not fully characterized. This study aims to ... -
The Metabolic Switch of Physical Activity in Non-Obese Insulin Resistant Individuals.
( MDPI , 2023 , Article)Healthy non-obese insulin resistant (IR) individuals are at higher risk of metabolic syndrome. The metabolic signature of the increased risk was previously determined. Physical activity can lower the risk of insulin ... -
Metabolomics Profiling of Stages of Coronary Artery Disease Progression
( Multidisciplinary Digital Publishing Institute (MDPI) , 2024 , Article)Coronary artery disease (CAD) and atherosclerosis pose significant global health challenges, with intricate molecular changes influencing disease progression. Hypercholesterolemia (HC), hypertension (HT), and diabetes are ... -
Metformin increases 3-hydroxy medium chain fatty acids in patients with type 2 diabetes: a cross-sectional pharmacometabolomic study
( Frontiers Media SA , 2024 , Article)Background: Metformin is a drug with a long history of providing benefits in diabetes management and beyond. The mechanisms of action of metformin are complex, and continue to be actively debated and investigated. The aim ... -
N-lactoyl amino acids are potential biomarkers for insulin resistance and diabetic complications
( Wiley , 2025 , Article)Aims: N-lactoyl amino acids (Lac-AA) are emerging as crucial players in metabolic research, with potential implications for disease mechanisms and therapeutic interventions. This study exploress the role of Lac-AA in insulin ... -
N-Lactoyl amino acids as metabolic biomarkers differentiating low and high exercise response
( Institute of Sport , 2025 , Article)Aerobic physical exercise has significant benefits for cardiovascular health; however, some individuals experience no benefit or even adverse effects. One reason for poor tolerance to aerobic exercise may be a low percentage ... -
N-Lactoyl amino acids: insights from metabolite genome-wide association studies and phenome-wide association analysis
( Oxford University Press , 2025 , Article)N-lactoyl-amino acids (Lac-AA) are emerging as important metabolites with diverse physiological roles. This study integrates metabolomics and genomics to investigate the genetic determinants and clinical relevance of three ... -
Pharmacogenomics and Pharmacometabolomics in Precision Tramadol Prescribing for Enhanced Pain Management: Evidence from QBB and EMR Data
( Multidisciplinary Digital Publishing Institute , 2025 , Article)Background/Objectives: Tramadol is an opioid frequently prescribed for moderate to severe pain and has seen a global increase in use. This presents numerous challenges in clinical management. This study aims to elucidate ... -
Pharmacometabolomic Approach to Investigate the Response to Metformin in Patients with Type 2 Diabetes: A Cross-Sectional Study
( MDPI , 2023 , Article)Metformin constitutes the foundation therapy in type 2 diabetes (T2D). Despite its multiple beneficial effects and widespread use, there is considerable inter-individual variability in response to metformin. Our objective ...
