Browsing by Author "Haque, Anzarul"
Now showing items 1-15 of 15
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Bronchodilator Monoterpenes from the Fruits of Trachyspermum ammi L.
( ACG Publications , 2024 , Article)Trachyspermum ammi is widely used among the people in the Arabian Peninsula to treat general respiratory problems including bronchoconstriction. In this study, the fruit extracts and its fractions and purely isolated ... -
Development of novel nanoemulsion of pioglitazone used in the treatment of diabetes and its gel form for the treatment of skin diseases
( Elsevier , 2024 , Article)Pioglitazone (PGL), an antidiabetic drug within the thiazolidinedione class, is utilized in managing type-2-diabetes-mellitus. Additionally, it has been observed to exhibit therapeutic effects on various inflammatory ... -
An Eco-Friendly and Sensitive Microwave-Aided Spectrofluorophotometric Characterization of Mirabegron-Loaded Nanocarriers by Amalgamation of Design of Experiments and White Analytical Chemistry
( John Wiley and Sons , 2024 , Article)Mirabegron, a drug for treatment of overactive bladder, has low water solubility and bioavailability. Researchers used quality by design to develop and characterize second-generation lipid nanocarriers for mirabegron, ... -
Eco-friendly green synthesis of silver nanoparticles utilizing olive oil waste by-product and their incorporation into a chitosan-aloe vera gel composite for enhanced wound healing in acid burn injuries
( Elsevier , 2024 , Article)This study focused on the green synthesis of silver nanoparticles (AgNPs) using olive oil waste by-product and their incorporation into Chitosan-Aloe-Vera gel (AgNPs/AV-CS gel). The synthesized AgNPs exhibited a hydrodynamic ... -
In-Vitro Dissolution Study of Solid Dispersion Adsorbate of Nateglinide by Eco-Friendly Liquid Chromatography-Tandem Mass Spectrometric Method through Harmonized Approach of White Analytical Chemistry and Analytical Quality by Design
( Springer Nature , 2024 , Article)Purpose: Nateglinide, a member of the meglitinide class, is used as an oral antihyperglycemic agent to treat non-insulin-dependent diabetes mellitus. It falls under the BCS class II category and has a low solubility ... -
In-vivo pharmacokinetic study of ibrutinib-loaded nanostructured lipid carriers in rat plasma by sensitive spectrofluorimetric method using harmonized approach of quality by design and white analytical chemistry
( Elsevier , 2024 , Article)Ibrutinib, an antineoplastic agent tackling chronic lymphocytic leukemia, mantle cell lymphoma, and Waldenstrom’s Macroglobulinemia, falls under the category of BCS class II drugs, characterized by a puzzling combination ... -
Integrated approach of white analytical chemistry and design of experiments to microwave-assisted sensitive and eco-friendly spectrofluorimetric estimation of mirabegron using 4-chloro-7-nitrobezofuran as biosensing fluorescent probe
( Elsevier , 2024 , Article)The USFDA recently approved mirabegron, a novel once-daily β-3 adrenoceptor agonist for oral administration, as a transformative treatment for overactive bladder. Despite the existence of numerous analytical methods for ... -
Lipid-based nanoparticles: innovations in ocular drug delivery
( Frontiers Media , 2024 , Article Review)Ocular drug delivery presents significant challenges due to intricate anatomy and the various barriers (corneal, tear, conjunctival, blood-aqueous, blood-retinal, and degradative enzymes) within the eye. Lipid-based ... -
Microwave-aided sensitive and eco-friendly HPTLC method for estimation of mirabegron using NBD-Cl as bio-sensing fluorescent probe by Integration of principal component Analysis, response surface modelling and white analytical chemistry approach
( Elsevier B.V. , 2024 , Article)A large number of analytical methods have been used in in-vivo pharmacokinetic investigations and assays of mirabegron, which is used to treat overactive bladder. Because mirabegron does not give fluorescence, there is no ... -
Microwave-derivatized enhanced-spectrofluorophotometric characterization of nateglinide-loaded solid dispersion adsorbate and greenness profile assessment of method
( Springer Nature , 2024 , Article)Nateglinide is an oral meglitinide that treats diabetes. Nateglinide was determined in several commercial formulations using chromatographic and spectrophotometric methods in published research. Quality-by-design approach ... -
A novel mucoadhesive paliperidone-nanoemulsion developed using the ultrasonication method in the treatment of schizophrenia
( Royal Society of Chemistry , 2024 , Article)Aim: To develop paliperidone mucoadhesive-nanoemulsion (PLP-NE) to enhance brain bioavailability. To evaluate comparative effects of PLP-NE and CS-PLP-NE in the treatment of schizophrenia, followed by a toxicity study of ... -
Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity.
( Wiley , 2024 , Article Review)One of the triazole tautomers, 1,2,4-triazole derivatives, has a wide range of biological activities that suggest its potential therapeutic utility in medicinal chemistry. These actions include anti-inflammatory, anti-cancer, ... -
Surface-engineered Niosomes of Esculin Hydrate for the management of depression via intranasal route: Optimization, In vitro, Ex vivo and pharmacokinetic assessment
( Elsevier B.V. , 2024 , Article)Present research explored the potential of surface-engineered niosomes of Esculin hydrate (ESCH), coated with chitosan, as a novel approach for managing depression through intranasal administration. Formulation optimization ... -
Targeting protein receptors and enzymes for precision management of urolithiasis: A comprehensive review
( Elsevier , 2024 , Article)Urolithiasis, characterized by the formation of solid crystalline structures within the urinary tract, presents a significant global health burden with high recurrence rates and limited treatment efficacy. Recent research ... -
Whiteness, redness, blueness and greenness profile assessment and design of experiments approach to microwave-aided sensitive and green spectrofluorophotometric determination of baclofen
( John Wiley & Sons Ltd. , 2024 , Article)As a gamma amino butyric acid-ergic agonist, Baclofen is often prescribed to adults and children for the treatment of severe spasticity that originates in the brain or spinal cord. Even after reviewing the literature ...
