Browsing by Author "Abdalhakam, Ibrahem"
Now showing items 1-6 of 6
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Characteristic MicroRNAs Linked to Dysregulated Metabolic Pathways in Qatari Adult Subjects With Obesity and Metabolic Syndrome.
Mir, Fayaz Ahmad; Mall, Raghvendra; Iskandarani, Ahmad; Ullah, Ehsan; Samra, Tareq A; Cyprian, Farhan; Parray, Aijaz; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Abou-Samra, Abdul-Badi... more authors ... less authors ( Frontiers , 2022 , Article)Obesity-associated dysglycemia is associated with metabolic disorders. MicroRNAs (miRNAs) are known regulators of metabolic homeostasis. We aimed to assess the relationship of circulating miRNAs with clinical features in ... -
Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome
Mir, Fayaz Ahmad; Ullah, Ehsan; Mall, Raghvendra; Iskandarani, Ahmad; Samra, Tareq A.; Cyprian, Farhan; Parray, Aijaz; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Abou-Samra, Abdul Badi... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic ... -
Hormonal predictors of the insulin sensitive phenotype in humans.
Ahmed, Mohamed Badie; Habib, Abdella M; Badran, Saif; Alsherawi, Abeer; Elnefaily, Sherouk Essam; Binfayed, Mansour; Hammouda, Atalla; Glass, Graeme E; Abdalhakam, Ibrahem; Rajha, Humam Emad; Abou-Samra, Abdul-Badi; Doi, Suhail A... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity, a chronic condition marked by excessive fat accumulation, often leads to insulin resistance and a heightened risk of comorbidities. This study aimed to identify hormonal predictors of an insulin-sensitive ... -
Hormonal predictors of the lean phenotype in humans.
Ahmed, Mohamed Badie; Habib, Abdella M; Badran, Saif; Alsherawi, Abeer; Al-Mohannadi, Fatima; Elnefaily, Sherouk Essam; Hammouda, Atalla; Glass, Graeme E; Abdalhakam, Ibrahem; Abou-Samra, Abdul-Badi; Doi, Suhail A... more authors ... less authors ( Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina , 2025 , Article)Clinical obesity is characterized by excessive fat accumulation and an increased risk of numerous associated comorbidities. Adipose tissue secretes leptin and other adipokines, which play key roles in regulating energy ... -
Inflammatory protein signatures in individuals with obesity and metabolic syndrome
Mir, Fayaz Ahmad; Abdesselem, Houari B.; Cyprian, Farhan; Iskandarani, Ahmad; Doudin, Asmma; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)There is variability in the metabolic health status among individuals presenting with obesity; some may be metabolically healthy, while others may have developed the metabolic syndrome, a cluster including insulin resistance, ... -
An integrated multi-omic approach demonstrates distinct molecular signatures between human obesity with and without metabolic complications: a case–control study
Mir, Fayaz Ahmad; Mall, Raghvendra; Ullah, Ehsan; Iskandarani, Ahmad; Cyprian, Farhan; Samra, Tareq A.; Alkasem, Meis; Abdalhakam, Ibrahem; Farooq, Faisal; Taheri, Shahrad; Abou-Samra, Abdul Badi... more authors ... less authors ( Springer Nature , 2023 , Article)Objectives: To examine the hypothesis that obesity complicated by the metabolic syndrome, compared to uncomplicated obesity, has distinct molecular signatures and metabolic pathways. Methods: We analyzed a cohort of 39 ...