Browsing by Author "Sang, Shengmin"

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Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway

Sampath, Chethan; Rashid, Muhammed; Sang, Shengmin; Ahmedna, Mohamed ( Elsevier , 2017 , Article)
Prolonged hyperglycemia activates the formation of advanced glycation end-products (AGEs). Major dicarbonyl compounds such as methylglyoxal or glyoxal are found to be the main precursors of AGEs and N(e)-(carboxymethyl)lysine ...
Tea flavanols block advanced glycation of lens crystallins induced by dehydroascorbic acid

Zhu, Yingdong; Zhao, Yantao; Wang, Pei; Ahmedna, Mohamed; Ho, Chi-Tang; Sang, Shengmin... more authors ... less authors ( American Chemical Society , 2015 , Article)
Growing evidence has shown that ascorbic acid (ASA) can contribute to protein glycation and the formation of advanced glycation end products (AGEs), especially in the lens. The mechanism by which ascorbic acid can cause ...