Browsing by Author "Mondello, Stefania"

Now showing items 1-10 of 10

    • Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 

      Stein Emil, Vollset; Ababneh, Hazim S; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and ...

    • Changing life expectancy in European countries 1990–2021: a subanalysis of causes and risk factors from the Global Burden of Disease Study 2021 

      Nicholas, Steel; Bauer-Staeb, Clarissa Maria Mercedes; Ford, John A; Abbafati, Cristiana; Abdalla, Mohammed Altigani; ... more authors ( Elsevier , 2025 , Article)
      BackgroundDecades of steady improvements in life expectancy in Europe slowed down from around 2011, well before the COVID-19 pandemic, for reasons which remain disputed. We aimed to assess how changes in risk factors and ...

    • The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model 

      Firas, Kobeissy; Mallah, Khalil; Zibara, Kazem; Dakroub, Fatima; Dalloul, Zeinab; ... more authors ( Elsevier , 2022 , Article)
      Traumatic Brain Injury (TBI) is one of the leading causes of death and disability worldwide. Aspirin (ASA) and clopidogrel (CLOP) are antiplatelet agents that inhibit platelet aggregation. They are implicated in worsening ...

    • G protein estrogen receptor as a potential therapeutic target in Raynaud’s phenomenon 

      Fardoun, Manal; Mondello, Stefania; Kobeissy, Firas; Eid, Ali H. ( Frontiers Media , 2022 , Article)
      Exaggerated cold-induced vasoconstriction can precipitate a pathogenesis called Raynaud’s phenomenon (RP). Interestingly, RP is significantly more prevalent in females than age-matched men, highlighting the potential ...

    • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Michael, Brauer; Roth, Gregory A; Aravkin, Aleksandr Y; Zheng, Peng; Abate, Kalkidan Hassen; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to ...

    • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Alize J, Ferrari; Santomauro, Damian Francesco; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2024 , Article)
      Background Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...

    • Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 

      Marie, Ng; Gakidou, Emmanuela; Lo, Justin; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2025 , Article)
      BackgroundOverweight and obesity is a global epidemic. Forecasting future trajectories of the epidemic is crucial for providing an evidence base for policy change. In this study, we examine the historical trends of the ...

    • Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 

      Jessica A, Kerr; Patton, George C; Cini, Karly I; Abate, Yohannes Habtegiorgis; Abbas, Nasir; ... more authors ( Elsevier , 2025 , Article)
      BackgroundDespite the well documented consequences of obesity during childhood and adolescence and future risks of excess body mass on non-communicable diseases in adulthood, coordinated global action on excess body mass ...

    • Hormones in experimental autoimmune encephalomyelitis (EAE) animal models 

      Ghareghani, Majid; Ghanbari, Amir; Eid, Ali; Shaito, Abdullah; Mohamed, Wael; ... more authors ( De Gruyter , 2021 , Article)
      Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) in which activated immune cells attack the CNS and cause inflammation and demyelination. While the etiology of MS is still ...

    • Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 

      Rafael, Lozano; Fullman, Nancy; Mumford, John Everett; Knight, Megan; Barthelemy, Celine M; ... more authors ( Elsevier , 2020 , Article)
      Background Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority ...