• Epac as a tractable therapeutic target 

      Hasan, Slika; Mansour, Hadi; Nasser, Suzanne A.; Shaito, Abdullah; Kobeissy, Firas; ... more authors ( Elsevier , 2023 , Article)
      In 1957, cyclic adenosine monophosphate (cAMP) was identified as the first secondary messenger, and the first signaling cascade discovered was the cAMP-protein kinase A (PKA) pathway. Since then, cAMP has received increasing ...
    • Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms 

      Hasan, Slika; Mansour, Hadi; Wehbe, Nadine; Nasser, Suzanne A.; Iratni, Rabah; ... more authors ( Elsevier , 2022 , Article)
      Cancer is a leading cause of morbidity and mortality around the globe. Reactive oxygen species (ROS) play contradicting roles in cancer incidence and progression. Antioxidants have attracted attention as emerging therapeutic ...