• Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy 

      Bhat, A.A.; Bhat, Ajaz A.; Nisar, Sabah; Maacha, Selma; Carneiro-Lobo, Tatiana Correa; ... more authors ( BMC , 2021 , Article Review)
      Esophageal cancer (EC) is a disease often marked by aggressive growth and poor prognosis. Lack of targeted therapies, resistance to chemoradiation therapy, and distant metastases among patients with advanced disease account ...
    • High–temporal resolution profiling reveals distinct immune trajectories following the first and second doses of COVID-19 mRNA vaccines 

      Rinchai, Darawan; Deola, Sara; Zoppoli, Gabriele; Kabeer, Basirudeen Syed Ahamed; Taleb, Sara; ... more authors ( American Association for the Advancement of Science , 2022 , Article)
      Knowledge of the mechanisms underpinning the development of protective immunity conferred by mRNA vaccines is fragmentary. Here, we investigated responses to coronavirus disease 2019 (COVID-19) mRNA vaccination via ...
    • Insights Into the Role of CircRNAs: Biogenesis, Characterization, Functional, and Clinical Impact in Human Malignancies 

      Nisar, Sabah; Bhat, Ajaz A.; Singh, Mayank; Karedath, Thasni; Rizwan, Arshi; ... more authors ( Frontiers Media , 2021 , Article Review)
      Circular RNAs (circRNAs) are an evolutionarily conserved novel class of non-coding endogenous RNAs (ncRNAs) found in the eukaryotic transcriptome, originally believed to be aberrant RNA splicing by-products with decreased ...
    • Liquid biopsy: a step closer to transform diagnosis, prognosis and future of cancer treatments 

      Lone, Saife N.; Nisar, Sabah; Masoodi, Tariq; Singh, Mayank; Rizwan, Arshi; ... more authors ( BMC , 2022 , Article Review)
      Over the past decade, invasive techniques for diagnosing and monitoring cancers are slowly being replaced by non-invasive methods such as liquid biopsy. Liquid biopsies have drastically revolutionized the field of clinical ...
    • miRNAs as novel immunoregulators in cancer 

      Saife N., Lone; Bhat, Ajaz A.; Wani, Nissar A.; Karedath, Thasni; Hashem, Sheema; ... more authors ( Elsevier , 2021 , Article Review)
      The immune system is a well-known vital regulator of tumor growth, and one of the main hallmarks of cancer is evading the immune system. Immune system deregulation can lead to immune surveillance evasion, sustained cancer ...
    • Tumor microenvironment: an evil nexus promoting aggressive head and neck squamous cell carcinoma and avenue for targeted therapy. 

      Bhat, Ajaz A; Yousuf, Parvaiz; Wani, Nissar A; Rizwan, Arshi; Chauhan, Shyam S; ... more authors ( Springer Nature , 2021 , Article Review)
      Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease with a poor prognosis for advanced-stage tumors. Recent clinical, genomic, and cellular studies have revealed the highly heterogeneous and ...