• A population study of clinically actionable genetic variation affecting drug response from the Middle East 

      Jithesh, Puthen Veettil; Abuhaliqa, Mohammed; Syed, Najeeb; Ahmed, Ikhlak; El Anbari, Mohammed; ... more authors ( Nature Research , 2022 , Article)
      Clinical implementation of pharmacogenomics will help in personalizing drug prescriptions and alleviate the personal and financial burden due to inefficacy and adverse reactions to drugs. However, such implementation is ...
    • Immunomodulatory effects of vitamin d supplementation in a deficient population 

      Garand, Mathieu; Toufiq, Mohammed; Singh, Parul; Huang, Susie Shih Yin; Tomei, Sara; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)
      In addition to its canonical functions, vitamin D has been proposed to be an important mediator of the immune system. Despite ample sunshine, vitamin D deficiency is prevalent (>80%) in the Middle East, resulting in a high ...
    • The role of polymorphisms in vitamin d-related genes in response to vitamin d supplementation 

      Tomei, Sara; Singh, Parul; Mathew, Rebecca; Mattei, Valentina; Garand, Mathieu; ... more authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2020 , Article)
      Background. Vitamin D deficiency represents a major healthcare problem. Vitamin D status is influenced by genetic and environmental determinants. Several observational studies have evaluated the association of single-nucleotide ...
    • Understanding the genetics of early onset obesity in a cohort of children from Qatar. 

      Mohammed, Idris; Haris, Basma; Al-Barazenji, Tara; Vasudeva, Dhanya; Tomei, Sara; ... more authors ( Oxford University Press , 2023 , Article)
      Monogenic obesity is a rare form of obesity due to pathogenic variants in genes implicated in the leptin-melanocortin signaling pathway and accounts for around 5% of severe early onset obesity. Mutations in the genes ...